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Q80SY4

- MIB1_MOUSE

UniProt

Q80SY4 - MIB1_MOUSE

Protein

E3 ubiquitin-protein ligase MIB1

Gene

Mib1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 106 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation By similarity. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.By similarity1 Publication

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri79 – 12648ZZ-typePROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri819 – 85436RING-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri866 – 90136RING-type 2PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri963 – 99634RING-type 3PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. ligase activity Source: UniProtKB-KW
    2. protein binding Source: IntAct
    3. ubiquitin-protein transferase activity Source: InterPro
    4. zinc ion binding Source: InterPro

    GO - Biological processi

    1. blood vessel development Source: MGI
    2. heart development Source: MGI
    3. heart looping Source: MGI
    4. in utero embryonic development Source: MGI
    5. negative regulation of neuron differentiation Source: MGI
    6. neural tube formation Source: MGI
    7. Notch signaling pathway Source: MGI
    8. positive regulation of endocytosis Source: MGI
    9. somitogenesis Source: MGI

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Notch signaling pathway, Ubl conjugation pathway

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    ReactomeiREACT_196589. Constitutive Signaling by NOTCH1 PEST Domain Mutants.
    REACT_196591. Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants.
    REACT_196643. Constitutive Signaling by NOTCH1 HD Domain Mutants.
    REACT_199384. Activated NOTCH1 Transmits Signal to the Nucleus.
    REACT_199411. NOTCH2 Activation and Transmission of Signal to the Nucleus.
    UniPathwayiUPA00143.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    E3 ubiquitin-protein ligase MIB1 (EC:6.3.2.-)
    Alternative name(s):
    DAPK-interacting protein 1
    Short name:
    DIP-1
    Mind bomb homolog 1
    Gene namesi
    Name:Mib1
    Synonyms:Dip1, Kiaa1323, Mib
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 18

    Organism-specific databases

    MGIiMGI:2443157. Mib1.

    Subcellular locationi

    Cytoplasmcytoskeletonmicrotubule organizing centercentrosomecentriolar satellite By similarity. Cytoplasm. Cell membrane
    Note: Displaced from centriolar satellites in response to cellular stress, such as ultraviolet light (UV) radiation or heat shock By similarity. Localizes to the plasma membrane.By similarity

    GO - Cellular componenti

    1. centrosome Source: Ensembl
    2. cytoplasmic vesicle Source: MGI
    3. nuclear membrane Source: Ensembl
    4. plasma membrane Source: UniProtKB-SubCell
    5. postsynaptic density Source: Ensembl

    Keywords - Cellular componenti

    Cell membrane, Cytoplasm, Cytoskeleton, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 10061006E3 ubiquitin-protein ligase MIB1PRO_0000055944Add
    BLAST

    Post-translational modificationi

    Ubiquitinated; this modification is inhibited in response to cellular stress, such as ultraviolet light (UV) radiation or heat shock By similarity. Ubiquitinated; possibly via autoubiquitination.By similarity2 Publications

    Keywords - PTMi

    Ubl conjugation

    Proteomic databases

    PaxDbiQ80SY4.
    PRIDEiQ80SY4.

    PTM databases

    PhosphoSiteiQ80SY4.

    Expressioni

    Tissue specificityi

    Detected in all tissues tested. Present in embryo, embryonic stem cells, bladder, skeletal muscle, bladder, uterus, testis, stomach, colon, ileum, trachea, lung, aorta, kidney, spleen, liver and vas deferens (at protein level). Highly expressed in testis.2 Publications

    Developmental stagei

    Highly expressed both in embryos and adult tissues. In E9.5 and E10.5 embryos, it is expressed in the tail bud, limb buds and somites. Expressed in the same pattern than MIB2 in the skin and intestine at postnatal day 1 (P1) and in the hair follicle in the skin in the adult.1 Publication

    Gene expression databases

    ArrayExpressiQ80SY4.
    BgeeiQ80SY4.
    CleanExiMM_MIB1.
    GenevestigatoriQ80SY4.

    Interactioni

    Subunit structurei

    Interacts with CEP131 and PCM1.By similarity

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    CMIPQ8IY222EBI-645227,EBI-7689652From a different organism.
    snx5Q6DI324EBI-645227,EBI-8574974From a different organism.

    Protein-protein interaction databases

    BioGridi230365. 11 interactions.
    IntActiQ80SY4. 5 interactions.
    MINTiMINT-1550820.

    Structurei

    3D structure databases

    ProteinModelPortaliQ80SY4.
    SMRiQ80SY4. Positions 15-70, 154-216, 355-779, 851-908, 953-1003.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini6 – 7469MIB/HERC2 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini143 – 22179MIB/HERC2 2PROSITE-ProRule annotationAdd
    BLAST
    Repeati430 – 46031ANK 1Add
    BLAST
    Repeati463 – 49230ANK 2Add
    BLAST
    Repeati496 – 52530ANK 3Add
    BLAST
    Repeati529 – 55830ANK 4Add
    BLAST
    Repeati562 – 59130ANK 5Add
    BLAST
    Repeati595 – 62733ANK 6Add
    BLAST
    Repeati631 – 66131ANK 7Add
    BLAST
    Repeati665 – 69430ANK 8Add
    BLAST
    Repeati698 – 72932ANK 9Add
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili935 – 96228Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Contains 9 ANK repeats.PROSITE-ProRule annotation
    Contains 2 MIB/HERC2 domains.PROSITE-ProRule annotation
    Contains 3 RING-type zinc fingers.PROSITE-ProRule annotation
    Contains 1 ZZ-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri79 – 12648ZZ-typePROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri819 – 85436RING-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri866 – 90136RING-type 2PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri963 – 99634RING-type 3PROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    ANK repeat, Coiled coil, Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiCOG0666.
    GeneTreeiENSGT00660000095288.
    HOVERGENiHBG068386.
    InParanoidiQ80SY4.
    KOiK10645.
    OMAiHDAISKE.
    OrthoDBiEOG7WHH8P.
    PhylomeDBiQ80SY4.
    TreeFamiTF324147.

    Family and domain databases

    Gene3Di1.25.40.20. 3 hits.
    3.30.40.10. 1 hit.
    InterProiIPR002110. Ankyrin_rpt.
    IPR020683. Ankyrin_rpt-contain_dom.
    IPR010606. Mib_Herc2.
    IPR001841. Znf_RING.
    IPR013083. Znf_RING/FYVE/PHD.
    IPR000433. Znf_ZZ.
    [Graphical view]
    PfamiPF00023. Ank. 2 hits.
    PF12796. Ank_2. 2 hits.
    PF06701. MIB_HERC2. 2 hits.
    PF00569. ZZ. 1 hit.
    [Graphical view]
    PRINTSiPR01415. ANKYRIN.
    SMARTiSM00248. ANK. 9 hits.
    SM00184. RING. 3 hits.
    SM00291. ZnF_ZZ. 1 hit.
    [Graphical view]
    SUPFAMiSSF48403. SSF48403. 1 hit.
    PROSITEiPS50297. ANK_REP_REGION. 1 hit.
    PS50088. ANK_REPEAT. 6 hits.
    PS51416. MIB_HERC2. 2 hits.
    PS50089. ZF_RING_2. 3 hits.
    PS01357. ZF_ZZ_1. 1 hit.
    PS50135. ZF_ZZ_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q80SY4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNSRNNRVM VEGVGARVVR GPDWKWGKQD GGEGHVGTVR SFESPEEVVV     50
    VWDNGTAANY RCSGAYDLRI LDSAPTGIKH DGTMCDTCRQ QPIIGIRWKC 100
    AECTNYDLCT VCYHGDKHHL RHRFYRITTP GSERVLLESR RKSKKITARG 150
    IFAGARVVRG VDWQWEDQDG GNGRRGKVTE IQDWSASSPH SAAYVLWDNG 200
    AKNLYRVGFE GMSDLKCVQD AKGGSFYRDH CPVLGEQNGN RNPGGLQIGD 250
    LVNIDLDLEI VQSLQHGHGG WTDGMFETLT TTGTVCGIDE DHDIVVQYPS 300
    GNRWTFNPAV LTKANIVRSG DAAQGAEGGT SQFQVGDLVQ VCYDLERIKL 350
    LQRGHGEWAE AMLPTLGKVG RVQQIYSDSD LKVEVCGTSW TYNPAAVSKV 400
    APAGSAISNA SGERLSQLLK KLFETQESGD LNEELVKAAA NGDVAKVEDL 450
    LKRPDVDVNG QCAGHTAMQA ASQNGHVDIL KLLLKQNVDV EAEDKDGDRA 500
    VHHAAFGDEG AVIEVLHRGS ADLNARNKRR QTPLHIAVNK GHLQVVKTLL 550
    DFGCHPSLQD SEGDTPLHDA ISKKRDDILA VLLEAGADVT ITNNNGFNAL 600
    HHAALRGNPS AMRVLLSKLP RPWIVDEKKD DGYTALHLAA LNNHVEVAEL 650
    LVHQGNANLD IQNVNQQTAL HLAVERQHTQ IVRLLVRAGA KLDIQDKDGD 700
    TPLHEALRHH TLSQLRQLQD MQDVGKVDAA WEPSKNTLIM GLGTQGAEKK 750
    SAASIACFLA ANGADLSIRN KKGQSPLDLC PDPSLCKALA KCHKEKVSGQ 800
    VGSRSPSMIS NDSETLEECM VCSDMKRDTL FGPCGHIATC SLCSPRVKKC 850
    LICKEQVQSR TKIEECVVCS DKKAAVLFQP CGHMCACENC ASLMKKCVQC 900
    RAVVERRVPF ITCCGGKSSE DPSDEISSGN IPVLQKDKDN TNVNADVQKL 950
    QQQLQDIKEQ TMCPVCLDRL KNMIFLCGHG TCQLCGDRMS ECPICRKAIE 1000
    RRILLY 1006
    Length:1,006
    Mass (Da):110,088
    Last modified:June 1, 2003 - v1
    Checksum:i5A8FE2A1BEE638DE
    GO

    Sequence cautioni

    The sequence AAH69870.1 differs from that shown. Reason: Chimeric cDNA.
    The sequence BAC38042.1 differs from that shown. Reason: Contaminating sequence. Sequence of unknown origin in the C-terminal part.
    The sequence AAH11287.1 differs from that shown. Reason: Erroneous initiation.
    The sequence AAN18022.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti742 – 7421L → F in BAC38042. (PubMed:16141072)Curated
    Sequence conflicti907 – 9071R → K in AAN18022. (PubMed:15824097)Curated
    Sequence conflicti907 – 9071R → K in AAX84653. (PubMed:15824097)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY245539 mRNA. Translation: AAO91933.1.
    AY149907 mRNA. Translation: AAN75492.1.
    AY147848 mRNA. Translation: AAN18022.1. Different initiation.
    AY974091 mRNA. Translation: AAX84653.1.
    AK053035 mRNA. Translation: BAC35245.1.
    AK080847 mRNA. Translation: BAC38042.1. Sequence problems.
    BC011287 mRNA. Translation: AAH11287.1. Different initiation.
    BC069870 mRNA. Translation: AAH69870.1. Sequence problems.
    BC083072 mRNA. Translation: AAH83072.1.
    AK129331 mRNA. Translation: BAC98141.1.
    CCDSiCCDS29058.1.
    RefSeqiNP_659109.2. NM_144860.2.
    XP_006525873.1. XM_006525810.1.
    XP_006525874.1. XM_006525811.1.
    UniGeneiMm.21500.

    Genome annotation databases

    EnsembliENSMUST00000052838; ENSMUSP00000054428; ENSMUSG00000024294.
    ENSMUST00000165555; ENSMUSP00000131712; ENSMUSG00000024294.
    GeneIDi225164.
    KEGGimmu:225164.
    UCSCiuc008ebc.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY245539 mRNA. Translation: AAO91933.1 .
    AY149907 mRNA. Translation: AAN75492.1 .
    AY147848 mRNA. Translation: AAN18022.1 . Different initiation.
    AY974091 mRNA. Translation: AAX84653.1 .
    AK053035 mRNA. Translation: BAC35245.1 .
    AK080847 mRNA. Translation: BAC38042.1 . Sequence problems.
    BC011287 mRNA. Translation: AAH11287.1 . Different initiation.
    BC069870 mRNA. Translation: AAH69870.1 . Sequence problems.
    BC083072 mRNA. Translation: AAH83072.1 .
    AK129331 mRNA. Translation: BAC98141.1 .
    CCDSi CCDS29058.1.
    RefSeqi NP_659109.2. NM_144860.2.
    XP_006525873.1. XM_006525810.1.
    XP_006525874.1. XM_006525811.1.
    UniGenei Mm.21500.

    3D structure databases

    ProteinModelPortali Q80SY4.
    SMRi Q80SY4. Positions 15-70, 154-216, 355-779, 851-908, 953-1003.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 230365. 11 interactions.
    IntActi Q80SY4. 5 interactions.
    MINTi MINT-1550820.

    PTM databases

    PhosphoSitei Q80SY4.

    Proteomic databases

    PaxDbi Q80SY4.
    PRIDEi Q80SY4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000052838 ; ENSMUSP00000054428 ; ENSMUSG00000024294 .
    ENSMUST00000165555 ; ENSMUSP00000131712 ; ENSMUSG00000024294 .
    GeneIDi 225164.
    KEGGi mmu:225164.
    UCSCi uc008ebc.1. mouse.

    Organism-specific databases

    CTDi 57534.
    MGIi MGI:2443157. Mib1.
    Rougei Search...

    Phylogenomic databases

    eggNOGi COG0666.
    GeneTreei ENSGT00660000095288.
    HOVERGENi HBG068386.
    InParanoidi Q80SY4.
    KOi K10645.
    OMAi HDAISKE.
    OrthoDBi EOG7WHH8P.
    PhylomeDBi Q80SY4.
    TreeFami TF324147.

    Enzyme and pathway databases

    UniPathwayi UPA00143 .
    Reactomei REACT_196589. Constitutive Signaling by NOTCH1 PEST Domain Mutants.
    REACT_196591. Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants.
    REACT_196643. Constitutive Signaling by NOTCH1 HD Domain Mutants.
    REACT_199384. Activated NOTCH1 Transmits Signal to the Nucleus.
    REACT_199411. NOTCH2 Activation and Transmission of Signal to the Nucleus.

    Miscellaneous databases

    ChiTaRSi MIB1. mouse.
    NextBioi 377558.
    PROi Q80SY4.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q80SY4.
    Bgeei Q80SY4.
    CleanExi MM_MIB1.
    Genevestigatori Q80SY4.

    Family and domain databases

    Gene3Di 1.25.40.20. 3 hits.
    3.30.40.10. 1 hit.
    InterProi IPR002110. Ankyrin_rpt.
    IPR020683. Ankyrin_rpt-contain_dom.
    IPR010606. Mib_Herc2.
    IPR001841. Znf_RING.
    IPR013083. Znf_RING/FYVE/PHD.
    IPR000433. Znf_ZZ.
    [Graphical view ]
    Pfami PF00023. Ank. 2 hits.
    PF12796. Ank_2. 2 hits.
    PF06701. MIB_HERC2. 2 hits.
    PF00569. ZZ. 1 hit.
    [Graphical view ]
    PRINTSi PR01415. ANKYRIN.
    SMARTi SM00248. ANK. 9 hits.
    SM00184. RING. 3 hits.
    SM00291. ZnF_ZZ. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48403. SSF48403. 1 hit.
    PROSITEi PS50297. ANK_REP_REGION. 1 hit.
    PS50088. ANK_REPEAT. 6 hits.
    PS51416. MIB_HERC2. 2 hits.
    PS50089. ZF_RING_2. 3 hits.
    PS01357. ZF_ZZ_1. 1 hit.
    PS50135. ZF_ZZ_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK."
      Jin Y., Blue E.K., Dixon S., Shao Z., Gallagher P.J.
      J. Biol. Chem. 277:46980-46986(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, UBIQUITINATION.
      Tissue: Urinary bladder.
    2. "Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta."
      Itoh M., Kim C.-H., Palardy G., Oda T., Jiang Y.-J., Maust D., Yeo S.-Y., Lorick K., Wright G.J., Ariza-McNaughton L., Weissman A.M., Lewis J., Chandrasekharappa S.C., Chitnis A.B.
      Dev. Cell 4:67-82(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: C3H.
    3. Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, UBIQUITINATION.
    4. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 349-1006.
      Strain: C57BL/6J.
      Tissue: Corpora quadrigemina and Head.
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 547-1006.
      Strain: 129 and FVB/N.
      Tissue: Embryo and Mammary tumor.
    6. "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Nagase T., Ohara O., Koga H.
      DNA Res. 10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 864-1006.
      Tissue: Embryonic tail.

    Entry informationi

    Entry nameiMIB1_MOUSE
    AccessioniPrimary (citable) accession number: Q80SY4
    Secondary accession number(s): Q5XK51
    , Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 5, 2005
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 106 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3