Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q807U4

- Q807U4_9INFA

UniProt

Q807U4 - Q807U4_9INFA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Neuraminidase

Gene

NA

Organism
Influenza A virus (A/Pheasant/HongKong/FY155/01(H5N1))
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Catalytic activityi

Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.SAAS annotation

Cofactori

Note: Binds 1 calcium ion per subunit.SAAS annotation

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseSAAS annotation, Hydrolase

Keywords - Ligandi

CalciumSAAS annotation, Metal-bindingSAAS annotation

Protein family/group databases

CAZyiGH34. Glycoside Hydrolase Family 34.

Names & Taxonomyi

Protein namesi
Submitted name:
NeuraminidaseImported
Gene namesi
Name:NAImported
OrganismiInfluenza A virus (A/Pheasant/HongKong/FY155/01(H5N1))Imported
Taxonomic identifieri222144 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesOrthomyxoviridaeInfluenzavirus A

Subcellular locationi

Virion membrane SAAS annotation. Host apical cell membrane SAAS annotation; Single-pass type II membrane protein SAAS annotation

GO - Cellular componenti

  1. host cell plasma membrane Source: UniProtKB-SubCell
  2. integral component of membrane Source: UniProtKB-KW
  3. virion membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Host cell membraneSAAS annotation, Host membrane, Membrane, VirionSAAS annotation

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Subunit structurei

Homotetramer.SAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ807U4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR001860. Glyco_hydro_34.
IPR011040. Sialidases.
[Graphical view]
PfamiPF00064. Neur. 1 hit.
[Graphical view]
SUPFAMiSSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q807U4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNPNQKIITI GSICMVIGIV SLMLQIGNII SIWISHSIQT GNQHQAEPCN
60 70 80 90 100
QSIITYENNT WVNQTYVNIS NTNLLTEKAV ASVTLAGNSS LCPISGWAVY
110 120 130 140 150
SKDNGIRIGS KGDVFVIREP FISCSHLECR TFFLTQGALL NDKHSNGTVK
160 170 180 190 200
DRSPYRTLMS CPVGEAPSPY NSRFESVAWS ASACHDGTSW LTIGISGPDN
210 220 230 240 250
GAVAVLKYNG IITDTIKSWR NNILRTQESE CACVNGSCFT VMTDGPSNGQ
260 270 280 290 300
ASYKIFKIEK GKVVKSVELN APNYHYEECS CYPDAGEITC VCRDNWHGSN
310 320 330 340 350
RPWVSFNQNL EYQIGYICSG VFGDNPRPND GTGSCGPVSP NGAYGIKGFS
360 370 380 390 400
FKYGNGVWIG RTKSTNSRSG FEMIWDPNGW TGTDSNFSVK QDIVAITDWS
410 420 430 440 450
GYSGSFVQHP ELTGVDCIRP CFWVELIRGR PKESTIWTSG SSISFCGVNS
460
DTVGWSWPDG AELPFTIDK
Length:469
Mass (Da):51,332
Last modified:June 1, 2003 - v1
Checksum:i7A3FA0052CBFE49C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei469 – 4691Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY221544 Viral cRNA. Translation: AAO46820.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY221544 Viral cRNA. Translation: AAO46820.1 .

3D structure databases

ProteinModelPortali Q807U4.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH34. Glycoside Hydrolase Family 34.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.120.10.10. 1 hit.
InterProi IPR001860. Glyco_hydro_34.
IPR011040. Sialidases.
[Graphical view ]
Pfami PF00064. Neur. 1 hit.
[Graphical view ]
SUPFAMi SSF50939. SSF50939. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Neurovirulence in mice of H5N1 influenza virus genotypes isolated from Hong Kong poultry in 2001."
    Lipatov A.S., Krauss S., Guan Y., Peiris M., Rehg J.E., Perez D.R., Webster R.G.
    J. Virol. 77:3816-3823(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A/Pheasant/HongKong/FY155/01Imported.

Entry informationi

Entry nameiQ807U4_9INFA
AccessioniPrimary (citable) accession number: Q807U4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: November 26, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)