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Q807U4

- Q807U4_9INFA

UniProt

Q807U4 - Q807U4_9INFA

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Protein
Submitted name: Neuraminidase
Gene
NA
Organism
Influenza A virus (A/Pheasant/HongKong/FY155/01(H5N1))
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.SAAS annotations

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseSAAS annotations, Hydrolase

Protein family/group databases

CAZyiGH34. Glycoside Hydrolase Family 34.

Names & Taxonomyi

Protein namesi
Submitted name:
NeuraminidaseImported
Gene namesi
Name:NAImported
OrganismiInfluenza A virus (A/Pheasant/HongKong/FY155/01(H5N1))Imported
Taxonomic identifieri222144 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesOrthomyxoviridaeInfluenzavirus A

Subcellular locationi

GO - Cellular componenti

  1. host cell plasma membrane Source: UniProtKB-SubCell
  2. integral component of membrane Source: UniProtKB-KW
  3. virion membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Host cell membraneSAAS annotations, Host membrane, Membrane, VirionSAAS annotations

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.SAAS annotations

Structurei

3D structure databases

ProteinModelPortaliQ807U4.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR001860. Glyco_hydro_34.
IPR011040. Sialidases.
[Graphical view]
PfamiPF00064. Neur. 1 hit.
[Graphical view]
SUPFAMiSSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q807U4-1 [UniParc]FASTAAdd to Basket

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MNPNQKIITI GSICMVIGIV SLMLQIGNII SIWISHSIQT GNQHQAEPCN    50
QSIITYENNT WVNQTYVNIS NTNLLTEKAV ASVTLAGNSS LCPISGWAVY 100
SKDNGIRIGS KGDVFVIREP FISCSHLECR TFFLTQGALL NDKHSNGTVK 150
DRSPYRTLMS CPVGEAPSPY NSRFESVAWS ASACHDGTSW LTIGISGPDN 200
GAVAVLKYNG IITDTIKSWR NNILRTQESE CACVNGSCFT VMTDGPSNGQ 250
ASYKIFKIEK GKVVKSVELN APNYHYEECS CYPDAGEITC VCRDNWHGSN 300
RPWVSFNQNL EYQIGYICSG VFGDNPRPND GTGSCGPVSP NGAYGIKGFS 350
FKYGNGVWIG RTKSTNSRSG FEMIWDPNGW TGTDSNFSVK QDIVAITDWS 400
GYSGSFVQHP ELTGVDCIRP CFWVELIRGR PKESTIWTSG SSISFCGVNS 450
DTVGWSWPDG AELPFTIDK 469
Length:469
Mass (Da):51,332
Last modified:June 1, 2003 - v1
Checksum:i7A3FA0052CBFE49C
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei469 – 4691Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY221544 Viral cRNA. Translation: AAO46820.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY221544 Viral cRNA. Translation: AAO46820.1 .

3D structure databases

ProteinModelPortali Q807U4.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH34. Glycoside Hydrolase Family 34.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.120.10.10. 1 hit.
InterProi IPR001860. Glyco_hydro_34.
IPR011040. Sialidases.
[Graphical view ]
Pfami PF00064. Neur. 1 hit.
[Graphical view ]
SUPFAMi SSF50939. SSF50939. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Neurovirulence in mice of H5N1 influenza virus genotypes isolated from Hong Kong poultry in 2001."
    Lipatov A.S., Krauss S., Guan Y., Peiris M., Rehg J.E., Perez D.R., Webster R.G.
    J. Virol. 77:3816-3823(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A/Pheasant/HongKong/FY155/01Imported.

Entry informationi

Entry nameiQ807U4_9INFA
AccessioniPrimary (citable) accession number: Q807U4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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