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Protein

Virion infectivity factor

Gene

vif

Organism
Human immunodeficiency virus 2
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Biological processi

Keywordsi

Biological processHost-virus interactionSAAS annotation, Ubl conjugation pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Virion infectivity factorUniRule annotation
Gene namesi
Name:vifImported
OrganismiHuman immunodeficiency virus 2Imported
Taxonomic identifieri11709 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Host cell membrane UniRule annotationSAAS annotation; Peripheral membrane protein UniRule annotationSAAS annotation; Cytoplasmic side UniRule annotationSAAS annotation
  • Host cytoplasm UniRule annotation
  • Virion UniRule annotationSAAS annotation
  • Note: In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Host cell membraneSAAS annotation, Host cytoplasmSAAS annotation, Host membrane, Membrane, VirionSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the primate lentivirus group Vif protein family.UniRule annotationSAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR000475 Viral_infect
PfamiView protein in Pfam
PF00559 Vif, 1 hit
PRINTSiPR00349 VIRIONINFFCT

Sequencei

Sequence statusi: Complete.

Q80637-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEGKRWIVV PTWRVPGRME KWHSLVKYLK YRTKDLEKVC YVPHHKVGWA
60 70 80 90 100
WWTCSRVIFP LQGKSHLEIQ AYWNLTPEKG WLSSYAVRIT WYTEKFWTDV
110 120 130 140 150
TPDCADSLIH GTYFSCFTAG EVRRAIRGEK LLSCCNYPQA HKSQVPSLQF
160 170 180 190 200
LALVVVQQNG KPQRNSTTRK QWRRDYRRGL RVARQDSRGL KQRGGESPAP
210
GAHFPGVAKV LDILA
Length:215
Mass (Da):25,031
Last modified:November 1, 1996 - v1
Checksum:i1E5A4B20A7118FA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L28934 Genomic DNA Translation: AAA56818.1

Similar proteinsi

Entry informationi

Entry nameiQ80637_9HIV2
AccessioniPrimary (citable) accession number: Q80637
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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