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Protein

Virion infectivity factor

Gene

vif

Organism
Human immunodeficiency virus 2
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Host-virus interactionSAAS annotation, Ubl conjugation pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Virion infectivity factorUniRule annotation
Gene namesi
Name:vifImported
OrganismiHuman immunodeficiency virus 2Imported
Taxonomic identifieri11709 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Host cell membrane SAAS annotation; Peripheral membrane protein SAAS annotation; Cytoplasmic side SAAS annotation
  • Host cytoplasm SAAS annotation
  • Virion SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Host cell membraneSAAS annotation, Host cytoplasmSAAS annotation, Host membrane, Membrane, VirionSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiQ80637.

Family & Domainsi

Sequence similaritiesi

Belongs to the primate lentivirus group Vif protein family.SAAS annotation

Family and domain databases

InterProiIPR000475. Viral_infect.
[Graphical view]
PfamiPF00559. Vif. 1 hit.
[Graphical view]
PRINTSiPR00349. VIRIONINFFCT.

Sequencei

Sequence statusi: Complete.

Q80637-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEGKRWIVV PTWRVPGRME KWHSLVKYLK YRTKDLEKVC YVPHHKVGWA
60 70 80 90 100
WWTCSRVIFP LQGKSHLEIQ AYWNLTPEKG WLSSYAVRIT WYTEKFWTDV
110 120 130 140 150
TPDCADSLIH GTYFSCFTAG EVRRAIRGEK LLSCCNYPQA HKSQVPSLQF
160 170 180 190 200
LALVVVQQNG KPQRNSTTRK QWRRDYRRGL RVARQDSRGL KQRGGESPAP
210
GAHFPGVAKV LDILA
Length:215
Mass (Da):25,031
Last modified:November 1, 1996 - v1
Checksum:i1E5A4B20A7118FA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L28934 Genomic DNA. Translation: AAA56818.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L28934 Genomic DNA. Translation: AAA56818.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ80637.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000475. Viral_infect.
[Graphical view]
PfamiPF00559. Vif. 1 hit.
[Graphical view]
PRINTSiPR00349. VIRIONINFFCT.
ProtoNetiSearch...

Publicationsi

  1. "Molecular characterization of vif genes from non syncytium inducing strains of human immunodeficiency virus type 2."
    Jacinto A., Ribeiro A.C., Taveira N., Moniz Pereira J., Barahona I.
    Submitted (DEC-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ALIImported.
  2. "HIV type 2 Vif proteins have specific conserved amino acid motifs."
    Ribeiro A.C., Moniz Pereira J., Barahona I.
    AIDS Res. Hum. Retroviruses 14:465-469(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ALIImported.

Entry informationi

Entry nameiQ80637_9HIV2
AccessioniPrimary (citable) accession number: Q80637
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.