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Protein

Serine/threonine-protein phosphatase

Gene

ppp2cb

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotation

Enzyme and pathway databases

ReactomeiR-DRE-1295596 Spry regulation of FGF signaling
R-DRE-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-DRE-195253 Degradation of beta-catenin by the destruction complex
R-DRE-196299 Beta-catenin phosphorylation cascade
R-DRE-2467813 Separation of Sister Chromatids
R-DRE-2500257 Resolution of Sister Chromatid Cohesion
R-DRE-5663220 RHO GTPases Activate Formins
R-DRE-68877 Mitotic Prometaphase

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
Gene namesi
Name:ppp2cbImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Unplaced

Organism-specific databases

ZFINiZDB-GENE-040426-2487 ppp2cb

Expressioni

Gene expression databases

BgeeiENSDARG00000099241

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000062145

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini114 – 119SER_THR_PHOSPHATASEInterPro annotation6

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0371 Eukaryota
COG0639 LUCA
GeneTreeiENSGT00550000074618
HOGENOMiHOG000172696
HOVERGENiHBG000216
KOiK04382
OMAiNWGHDKN
OrthoDBiEOG091G0B6S
TreeFamiTF105559

Family and domain databases

Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR006186 Ser/Thr-sp_prot-phosphatase
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PRINTSiPR00114 STPHPHTASE
SMARTiView protein in SMART
SM00156 PP2Ac, 1 hit
PROSITEiView protein in PROSITE
PS00125 SER_THR_PHOSPHATASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q803G3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDKAFTKEL DQWVEQLNEC KQLTENQVRT LCEKAKEILT KESNVQEVRC
60 70 80 90 100
PVTVCGDVHG QFHDLMELFR IGGKSPDTNY LFMGDYVDRG YYSVETVTLL
110 120 130 140 150
VALKVRYPER ITILRGNHES RQITQVYGFY DECLRKYGNA NVWKYFTDLF
160 170 180 190 200
DYLPLTALVD GQIFCLHGGL SPSIDTLDHI RALDRLQEVP HEGPMCDLLW
210 220 230 240 250
SDPDDRGGWG ISPRGAGYTF GQDISETFNH ANGLTLVSRA HQLVMEGYNW
260 270 280 290 300
CHDRNVVTIF SAPNYCYRCG NQAAIMELDD TLKYSFLQFD PAPRRGEPHV

TRRTPDYFL
Length:309
Mass (Da):35,562
Last modified:June 1, 2003 - v1
Checksum:iFDB31D0851395CD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX537303 Genomic DNA No translation available.
BC044495 mRNA Translation: AAH44495.1
BC065680 mRNA Translation: AAH65680.1
RefSeqiNP_998458.1, NM_213293.1
UniGeneiDr.143437
Dr.76775

Genome annotation databases

EnsembliENSDART00000162617; ENSDARP00000140225; ENSDARG00000099241
ENSDART00000191794; ENSDARP00000157451; ENSDARG00000111489
GeneIDi406582
KEGGidre:406582

Similar proteinsi

Entry informationi

Entry nameiQ803G3_DANRE
AccessioniPrimary (citable) accession number: Q803G3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: June 20, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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