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Protein
Submitted name:

Heat shock 60 protein 1

Gene

hspd1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • 'de novo' protein folding Source: GO_Central
  • apoptotic mitochondrial changes Source: GO_Central
  • chaperone-mediated protein folding Source: GO_Central
  • fin regeneration Source: ZFIN
  • protein import into mitochondrial intermembrane space Source: GO_Central
  • protein refolding Source: InterPro
  • regulation of cytokine production Source: GO_Central
  • T cell activation Source: GO_Central
  • tissue regeneration Source: ZFIN

Keywordsi

Biological processStress responseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Heat shock 60 protein 1Imported
Submitted name:
Heat shock 60kD protein 1 (Chaperonin)Imported
Submitted name:
Hspd1 proteinImported
Gene namesi
Name:hspd1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 9

Organism-specific databases

ZFINiZDB-GENE-021206-1. hspd1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSDARG00000056160.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

MINTiMINT-8283560.
STRINGi7955.ENSDARP00000073057.

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili364 – 395Sequence analysisAdd BLAST32

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0356. Eukaryota.
COG0459. LUCA.
GeneTreeiENSGT00390000005727.
HOGENOMiHOG000076290.
HOVERGENiHBG001982.
OMAiTDTDKME.
OrthoDBiEOG091G04JM.
TreeFamiTF300475.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR037290. Cpn60/TCP-1_sf.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

Q803B0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRLPSVMRQ MRPVCRALAP HLTRAYAKDV KFGADARALM LQGVDLLADA
60 70 80 90 100
VAVTMGPKGR TVIIEQSWGS PKVTKDGVTV AKSIDLKDRY KNIGAKLVQD
110 120 130 140 150
VANNTNEEAG DGTTTATVLA RAVAKEGFDT ISKGANPVEI RRGVMMAVEE
160 170 180 190 200
VISELKKNSK PVTTPEEIAQ VATISANGDT EVGNIISNAM KKVGRKGVIT
210 220 230 240 250
VKDGKTLHDE LEIIEGMKFD RGYISPYFIN TAKGQKCEFQ DAYVLLSEKK
260 270 280 290 300
ISSVQSIVPA LEIANQHRKP LVIVAEDVDG EALSTLVLNR LKVGLQVVAV
310 320 330 340 350
KAPGFGDNRK NQLQDMAVST GGTVFGDEAM GLALEDIQAH DFGKVGEVIV
360 370 380 390 400
TKDDTMLLKG RGDASAIEKR VNEIAEQLES TNSDYEKEKL NERLAKLSDG
410 420 430 440 450
VAVIKVGGTS DVEVNEKKDR VTDALNATRA AVEEGIVPGG GCALLRCIPA
460 470 480 490 500
LDNIKPANAD QKIGIDIIRR SLRIPAMTIA KNAGVEGSLV VEKILQSSTE
510 520 530 540 550
IGYDAMNGEY VNMVERGIID PTKVVRTALL DAAGVASLLS TAEAVVTEIP
560 570
KEEKEMPAGG MGGMGGMGGM GGMGF
Length:575
Mass (Da):61,196
Last modified:June 1, 2003 - v1
Checksum:iCA94CBE74AB6CC77
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX530407 Genomic DNA. No translation available.
BC044557 mRNA. Translation: AAH44557.1.
BC068415 mRNA. Translation: AAH68415.1.
RefSeqiNP_851847.1. NM_181330.3.
UniGeneiDr.75320.

Genome annotation databases

EnsembliENSDART00000078596; ENSDARP00000073057; ENSDARG00000056160.
ENSDART00000127938; ENSDARP00000107955; ENSDARG00000056160.
GeneIDi282676.

Similar proteinsi

Entry informationi

Entry nameiQ803B0_DANRE
AccessioniPrimary (citable) accession number: Q803B0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: November 22, 2017
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported