Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Peptidylprolyl isomerase

Gene

fkbp5

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase, RotamasePROSITE-ProRule annotation

Enzyme and pathway databases

ReactomeiR-DRE-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR)
R-DRE-8939211 ESR-mediated signaling

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidylprolyl isomerasePROSITE-ProRule annotation (EC:5.2.1.8PROSITE-ProRule annotation)
Gene namesi
Name:fkbp5Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 6

Organism-specific databases

ZFINiZDB-GENE-030616-630 fkbp5

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSDARG00000028396

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000038578

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 138PPIase FKBP-typeInterPro annotationAdd BLAST89
Domaini165 – 251PPIase FKBP-typeInterPro annotationAdd BLAST87
Repeati268 – 301TPRPROSITE-ProRule annotationAdd BLAST34
Domaini317 – 384TPR_REGIONInterPro annotationAdd BLAST68
Repeati317 – 350TPRPROSITE-ProRule annotationAdd BLAST34
Repeati351 – 384TPRPROSITE-ProRule annotationAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili247 – 267Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0543 Eukaryota
COG0545 LUCA
GeneTreeiENSGT00760000119159
HOGENOMiHOG000256916
HOVERGENiHBG051624
KOiK09571
OMAiNSEETPM
OrthoDBiEOG091G07OA

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR031210 FKBP5
IPR023566 PPIase_FKBP
IPR001179 PPIase_FKBP_dom
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PANTHERiPTHR10516 PTHR10516, 2 hits
PTHR10516:SF26 PTHR10516:SF26, 2 hits
PfamiView protein in Pfam
PF00254 FKBP_C, 2 hits
SMARTiView protein in SMART
SM00028 TPR, 3 hits
SUPFAMiSSF48452 SSF48452, 1 hit
PROSITEiView protein in PROSITE
PS50059 FKBP_PPIASE, 2 hits
PS50005 TPR, 3 hits
PS50293 TPR_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

Q801U5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLEDIFST NQCPTAVFTS RGTAVTPNGD SGVCKIVKQH GVEGERPMIG
60 70 80 90 100
DRVFVHYTGR LLSGKKFDSS LDRKEPFVFN VGKGQVIKAW DICVCSMQKG
110 120 130 140 150
EVCLMLCKPE YAYGSAGSPP KVPPNSTLVF EIELLNFRGE ELTEDGGIVR
160 170 180 190 200
RIKVKGEGYS NPNEGATVHV HLEGWCGGRL FDSRDVTFAV GESEDVGVPL
210 220 230 240 250
GVDRAMEKLQ KGECCLLYLK PKYAFGKEGR KEHDIGSNAE LLYEVTLKDF
260 270 280 290 300
EKAKETWEMD LKEKLERAVL VKQKGTQYFK AGRYNYAVIQ YQRIVNWLEM
310 320 330 340 350
ECGNGKEQLQ AIQALLLVAH LNLALCYLRL REYSQTVENC NKVMELDPEN
360 370 380 390 400
EKALYRRGEA RLLRNEFSLA LMDFKQVLQV NSFNRAARSQ ILICQHKIRE
410 420 430 440 450
HHERDKKIYA NMFQRFAEHD AKVCRLKRKK EESVISDQNK QGLKRARLSQ

DGS
Length:453
Mass (Da):51,482
Last modified:June 1, 2003 - v1
Checksum:iEBF5FB0BDCFBCC1C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732567 Genomic DNA No translation available.
BC054610 mRNA Translation: AAH54610.1
RefSeqiNP_998314.1, NM_213149.1
UniGeneiDr.78793

Genome annotation databases

EnsembliENSDART00000028373; ENSDARP00000038578; ENSDARG00000028396
GeneIDi368924
KEGGidre:368924

Similar proteinsi

Entry informationi

Entry nameiQ801U5_DANRE
AccessioniPrimary (citable) accession number: Q801U5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health