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Protein

Alpha-1,4 glucan phosphorylase

Gene

pygm

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.UniRule annotation

Catalytic activityi

((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase
Biological processCarbohydrate metabolismUniRule annotation
LigandPyridoxal phosphateUniRule annotation

Protein family/group databases

CAZyiGT35. Glycosyltransferase Family 35.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-1,4 glucan phosphorylaseUniRule annotation (EC:2.4.1.1UniRule annotation)
Gene namesi
Name:pygmImported
ORF Names:XELAEV_18026582mgImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus
Proteomesi
  • UP000186698 Componenti: Chromosome 5l

Organism-specific databases

XenbaseiXB-GENE-955307. pygm.

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei681N6-(pyridoxal phosphate)lysineUniRule annotation1

Family & Domainsi

Sequence similaritiesi

Belongs to the glycogen phosphorylase family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG006848.
KOiK00688.

Family and domain databases

CDDicd04300. GT1_Glycogen_Phosphorylase. 1 hit.
InterProiView protein in InterPro
IPR011833. Glycg_phsphrylas.
IPR000811. Glyco_trans_35.
IPR035090. Pyridoxal_P_attach_site.
PANTHERiPTHR11468. PTHR11468. 1 hit.
PfamiView protein in Pfam
PF00343. Phosphorylase. 1 hit.
PIRSFiPIRSF000460. Pprylas_GlgP. 1 hit.
TIGRFAMsiTIGR02093. P_ylase. 1 hit.
PROSITEiView protein in PROSITE
PS00102. PHOSPHORYLASE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q801T6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATPLSDSDK KKQISVRGIA GLGDVSEVRK SFNRHLHFTL VKDRNVSTPR
60 70 80 90 100
DYYFALAHTV RDHLVGRWIR TQQYYYEKDP KRIYYLSLEF YMGRTLQNTM
110 120 130 140 150
LNLGLQHACD EAIYQLGLDM EELEEIEEDA GLGNGGLGRL AACFLDSMAT
160 170 180 190 200
LGLAAYGYGI RYEFGIFNQR IMNGWQVEEA DDWLRYGNPW EKARPEYMLP
210 220 230 240 250
VHFYGRVEHT AEGPKWVDTQ IVMAMPYDTP VPGYKNNTVN TMRLWSAKAP
260 270 280 290 300
NEFNLQEFNV GDYIEAVLDR NLAENISRVL YPNDNFFEGK ELRLKQEYFV
310 320 330 340 350
VAATLQDIIR RFKSSKFGCR DPVRTCFDTF PDKVAIQLND THPALAIPEL
360 370 380 390 400
MRILVDVEKV DWDRAWEVTK KTCAYTNHTV LPEALERWPV HLFEKLLPRH
410 420 430 440 450
LEIIYAINQK HLDEVASTFP GDMDRMRRMS IIEEGDCKRI NMANLCVIGS
460 470 480 490 500
HAVNGVARIH SEIVKNSVFN DFYDLEPNKF QNKTNGITPR RWLMLCNPGL
510 520 530 540 550
SDIIAEKIGE DFVTDLSQLR KLLDFVDDES FVHDVAKVKQ ENKLKFAAYL
560 570 580 590 600
EQEYKVKINP SSVFDVHVKR IHEYKRQLLN CLHIINLYNR IKKDPSKVFV
610 620 630 640 650
PRTVIIGGKA APGYHMAKMI IKLINSIASI VNSDPVIGDR LKVIFLENYR
660 670 680 690 700
VSLAEKVIPA ADLSQQISTA GTEASGTGNM KFMLNGALTI GTMDGANVEM
710 720 730 740 750
AEEAGEENLF IFGMRVEDVE ALDKKGYNAR DYYDRIPDLR QAIDQISDGH
760 770 780 790 800
FSPREPDLFK DVVNMLLNHD RFKVFADYED YIKSQKKVDQ LYMNPREWTK
810 820 830 840
KVIRNIACSG KFSSDRTISE YATEIWGVEP SAVKIPPPNI PRE
Length:843
Mass (Da):96,868
Last modified:June 1, 2003 - v1
Checksum:i8B1A855933440647
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC047245 mRNA. Translation: AAH47245.1.
CM004474 Genomic DNA. Translation: OCT79772.1.
RefSeqiNP_001080170.1. NM_001086701.1.
UniGeneiXl.20763.

Genome annotation databases

GeneIDi379862.
KEGGixla:379862.

Similar proteinsi

Entry informationi

Entry nameiQ801T6_XENLA
AccessioniPrimary (citable) accession number: Q801T6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: October 25, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported