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Q801R8 (GPD1L_XENLA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycerol-3-phosphate dehydrogenase 1-like protein

EC=1.1.1.8
Gene names
Name:gpd1l
OrganismXenopus laevis (African clawed frog)
Taxonomic identifier8355 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Plays a role in regulating cardiac sodium current By similarity.

Catalytic activity

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 352352Glycerol-3-phosphate dehydrogenase 1-like protein
PRO_0000286515

Regions

Nucleotide binding13 – 186NAD By similarity
Region272 – 2732Substrate binding By similarity

Sites

Active site2071Proton acceptor By similarity
Binding site441NAD By similarity
Binding site1001NAD By similarity
Binding site1231Substrate By similarity
Binding site1561NAD; via amide nitrogen By similarity
Binding site2721NAD By similarity
Binding site2991NAD; via amide nitrogen By similarity
Binding site3011NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q801R8 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 942B4DAEE369B1EB

FASTA35238,500
        10         20         30         40         50         60 
MALAGPLKVC IVGSGNWGSA VAKIIGHNVK NMKKFASTVN MWVFEENING RKLTEIINTE 

        70         80         90        100        110        120 
HENVKYLPGH KLPENVVALP NLTDAVRDAD LLIFVIPHQF IHKVCQEISG KVHKNALGIT 

       130        140        150        160        170        180 
LIKGIDEGPE GLRLISDIIR EKMNIDVSVL MGANIANEVA AEKFCETTIG SKNKNHGLLF 

       190        200        210        220        230        240 
KELLQTPNFR ITVVEDADTV ELCGALKNIV AVAAGFCDGL SCGDNTKAAV IRLGLMEMIA 

       250        260        270        280        290        300 
FANVFCKDSV SIATFLESCG VADLITTCYG GRNRKVAEAF VKTGKSIEEL EKEMLNGQKL 

       310        320        330        340        350 
QGPQTSAEVY RILQQKNMVN NFPLFTAVFQ ICYEGKPVED VISCLQSHPE HM 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Embryo.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC047958 mRNA. Translation: AAH47958.1.
BC108481 mRNA. Translation: AAI08482.1.
RefSeqNP_001080270.1. NM_001086801.1.
UniGeneXl.4022.

3D structure databases

ProteinModelPortalQ801R8.
SMRQ801R8. Positions 5-347.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ801R8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID379962.
KEGGxla:379962.

Organism-specific databases

CTD23171.
XenbaseXB-GENE-969908. gpd1l.

Phylogenomic databases

HOVERGENHBG003669.
KOK00006.

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11728. PTHR11728. 1 hit.
PfamPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSPR00077. GPDHDRGNASE.
SUPFAMSSF48179. SSF48179. 1 hit.
TIGRFAMsTIGR03376. glycerol3P_DH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGPD1L_XENLA
AccessionPrimary (citable) accession number: Q801R8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families