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Protein
Submitted name:

Zinc finger transcription factor detour

Gene

gli1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • abducens nerve development Source: ZFIN
  • abducens nucleus development Source: ZFIN
  • adenohypophysis development Source: ZFIN
  • adenohypophysis morphogenesis Source: ZFIN
  • brain development Source: ZFIN
  • cranial nerve development Source: ZFIN
  • facial nerve development Source: ZFIN
  • facial nucleus development Source: ZFIN
  • floor plate formation Source: ZFIN
  • generation of neurons Source: ZFIN
  • glossopharyngeal nerve development Source: ZFIN
  • muscle cell fate specification Source: ZFIN
  • neural tube patterning Source: ZFIN
  • neuron differentiation Source: ZFIN
  • odontogenesis Source: ZFIN
  • pituitary gland development Source: ZFIN
  • positive regulation of cell proliferation Source: InterPro
  • positive regulation of smoothened signaling pathway Source: ZFIN
  • positive regulation of transcription, DNA-templated Source: InterPro
  • regulation of neurogenesis Source: ZFIN
  • regulation of transcription, DNA-templated Source: ZFIN
  • retinal ganglion cell axon guidance Source: ZFIN
  • smoothened signaling pathway Source: ZFIN
  • trigeminal motor nucleus development Source: ZFIN
  • trigeminal nerve development Source: ZFIN
  • vagus nerve development Source: ZFIN
  • ventral spinal cord interneuron specification Source: ZFIN
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger transcription factor detourImported
Gene namesi
Name:gli1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-030321-1. gli1.

Subcellular locationi

GO - Cellular componenti

  • Hedgehog signaling complex Source: ZFIN
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ800Z9.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000049150.

Structurei

3D structure databases

ProteinModelPortaliQ800Z9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini302 – 334C2H2-typeInterPro annotationAdd BLAST33
Domaini340 – 367C2H2-typeInterPro annotationAdd BLAST28
Domaini368 – 397C2H2-typeInterPro annotationAdd BLAST30
Domaini398 – 428C2H2-typeInterPro annotationAdd BLAST31
Domaini429 – 459C2H2-typeInterPro annotationAdd BLAST31

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000290688.
HOVERGENiHBG005844.
KOiK16797.
PhylomeDBiQ800Z9.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR032850. GLI1.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR19818:SF2. PTHR19818:SF2. 4 hits.
SMARTiSM00355. ZnF_C2H2. 5 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q800Z9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVDMQPHQG LYHYDNTSNQ PSRGLAPSVR SPYSSEASSV CVALSGGQSV
60 70 80 90 100
NSREMYNPSM APGACMEPYM RAPHAPPPHS MMGHRGMPPP EGMSGAPYCN
110 120 130 140 150
QNMMTSHHNL PHNQHTSELM ASGDASCFST PRSMLKLSKK RALSISPLSD
160 170 180 190 200
ASVDLQTVIR TSPNSLVAFV NSRCGPNNPS SYGHLSVGTM SPSLGFSSSI
210 220 230 240 250
NYSRPQGNIY SHPVPSCIGA PARLPPHNPR LHTPAKHTHL KTEPVLGSVM
260 270 280 290 300
DSINIKGLED HSEGDVASPS STGTQDPLLG LLEGRDDLDK EEKPEPEAIY
310 320 330 340 350
ETNCHWESCS KEFDTQEQLV HHINNEHIHG EKKEFVCHWK DCSREQRPFK
360 370 380 390 400
AQYMLVVHMR RHTGEKPHKC TFEGCNKAYS RLENLKTHLR SHTGEKPYVC
410 420 430 440 450
EHEGCNKAFS NASDRAKHQN RTHSNEKPYI CKIPGCTKRY TDPSSLRKHV
460 470 480 490 500
KTVHGPEAHI TKKHRGDTGP RPPGLTTAGQ SSELLIEKEE RNREDCKLLA
510 520 530 540 550
PDNTLKSQPS PGGQSSCSSE RSPLGSANNN DSGVEMNLNA AGSLEDLTTQ
560 570 580 590 600
EDSGNAGVSE SSATISSGGM CMSVQALKRL ENLKIDKLKQ IRRPTPPGRN
610 620 630 640 650
AGNKLPALSA TGEMMSMCAP SPLLSNRRVM ELSAPDMGGV TGMSCPPNDR
660 670 680 690 700
RGSGTSSLSS AYTVSRRSSM VSPYLSSRRS SDVSHCQSVM GGEVPGDPLS
710 720 730 740 750
PQNSQRAGLC QNSGGLPGLP SLTPAQQYSL KAKYAAATGG PPPTPLPNMD
760 770 780 790 800
QAGTPARHVG FLRECQGQPL PPFLQQGGTR RHSANAEYGT GVIYPHQAPG
810 820 830 840 850
NNTRRASDPV RSAADPQGLP KVQRFNSLSN VSLMSRRNAL QQCGSDAALS
860 870 880 890 900
RHMYSPRPPS ITENVMMEAM GMDGNTEGRQ QGNMIPGGDR SYMGYQHNPH
910 920 930 940 950
QASQLSPGQE SLGCIDQVYQ SQMQGQYQRE ESCSTGVMGQ ADIANNLLQQ
960 970 980 990 1000
AEYGMSTCQL SPSGPHYPSQ GDGSGPWGQT NQLHSPGMQY QGAGMQGQHY
1010 1020 1030 1040 1050
TQQGIYDPTS NPNLQRVTVK PEQFHPSMGG SSSCQNTKAL HQNRHNANMQ
1060 1070 1080 1090 1100
TYPLQGQGIM NRSSSASCDF HHSQMGTQPN QGGSFQSGTG INLALAESRR
1110 1120 1130 1140 1150
SQTPMHQMKE MMVRNYVQSQ QALLWEQQQE QSVSEKPDGM DMGQTQMMQH
1160 1170 1180 1190 1200
SPQHQQANQN LYPGNTYQGY PNQNLMSPQQ NRVPGSVKEQ MQSSCYGPDM
1210 1220 1230 1240 1250
IPRPPQVRKS LSRQNSLSQQ AGGAYLGSPP HLSPVHSTAS PRRGVRLPPV
1260 1270 1280 1290 1300
QQQQQQQQQH SENFNNNNNP MYYSGQMHMH HDLEKTPEGP CLAQQHLTSS
1310 1320 1330 1340 1350
DPTTKPTSIS YPDPAPMSNA LEHLDLENAQ IDFTSIIDDQ EPSSYSPINA
1360 1370 1380 1390 1400
PIGHNQCSSQ TSSRLTTPQN SITLPSGLSN MAIGDMSSML TSLAGENKYL

NTLS
Length:1,404
Mass (Da):152,833
Last modified:June 1, 2003 - v1
Checksum:i08BAE9FE8385EC99
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY173030 mRNA. Translation: AAO43495.1.
RefSeqiNP_840081.1. NM_178296.2.
UniGeneiDr.88778.

Genome annotation databases

GeneIDi352930.
KEGGidre:352930.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY173030 mRNA. Translation: AAO43495.1.
RefSeqiNP_840081.1. NM_178296.2.
UniGeneiDr.88778.

3D structure databases

ProteinModelPortaliQ800Z9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000049150.

Proteomic databases

PaxDbiQ800Z9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi352930.
KEGGidre:352930.

Organism-specific databases

CTDi2735.
ZFINiZDB-GENE-030321-1. gli1.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000290688.
HOVERGENiHBG005844.
KOiK16797.
PhylomeDBiQ800Z9.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR032850. GLI1.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR19818:SF2. PTHR19818:SF2. 4 hits.
SMARTiSM00355. ZnF_C2H2. 5 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 5 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ800Z9_DANRE
AccessioniPrimary (citable) accession number: Q800Z9
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: October 5, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.