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Protein

Surfeit locus protein 4

Gene

SURF4

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi.By similarity

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-GGA-6811434. COPI-dependent Golgi-to-ER retrograde traffic.

Names & Taxonomyi

Protein namesi
Recommended name:
Surfeit locus protein 4
Gene namesi
Name:SURF4
Synonyms:SURF-4
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 17

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei64 – 8421HelicalSequence analysisAdd
BLAST
Transmembranei92 – 11221HelicalSequence analysisAdd
BLAST
Transmembranei157 – 17721HelicalSequence analysisAdd
BLAST
Transmembranei179 – 19921HelicalSequence analysisAdd
BLAST
Transmembranei203 – 22321HelicalSequence analysisAdd
BLAST
Transmembranei242 – 26221HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 269269Surfeit locus protein 4PRO_0000293484Add
BLAST

Proteomic databases

PaxDbiQ800K9.
PRIDEiQ800K9.

Expressioni

Gene expression databases

BgeeiENSGALG00000028265.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000005035.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi266 – 2694Di-lysine motifSequence analysis

Domaini

The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.By similarity

Sequence similaritiesi

Belongs to the SURF4 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3998. Eukaryota.
COG2259. LUCA.
GeneTreeiENSGT00530000064123.
HOGENOMiHOG000206959.
HOVERGENiHBG054238.
InParanoidiQ800K9.
OMAiDQLWYLQ.
OrthoDBiEOG091G0H3P.
PhylomeDBiQ800K9.
TreeFamiTF300001.

Family and domain databases

InterProiIPR002995. Surf4.
[Graphical view]
PfamiPF02077. SURF4. 1 hit.
[Graphical view]
PROSITEiPS01339. SURF4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q800K9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQNDIMSTA EDFADQFLRV TKQYLPHVAR LCLISTFLED GIRMWFQWSE
60 70 80 90 100
QRDYIDGTWN CGYFLASIFV FINLFGQLSG CILVLSRNFV QYACFGLFGI
110 120 130 140 150
IALQTIAYSI LWDLKFLMRN LALGGGLLLL LAESRSEGKS MFAGVPTMRE
160 170 180 190 200
SSPKQYMQLG GRVLLVLMFM TLLHFDMNFF YILQNIVGTA LIILVAIGFK
210 220 230 240 250
TKLAALTLVI WLFGINIYFN AFWTIPAYKP MHDFLKYDFF QTMSVIGGLL
260
LVVALGPGGV SMDEKKKEW
Length:269
Mass (Da):30,619
Last modified:June 1, 2003 - v1
Checksum:i946DB350286B0D84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB050010 mRNA. Translation: BAC65172.1.
RefSeqiNP_989686.1. NM_204355.1.
UniGeneiGga.9460.

Genome annotation databases

EnsembliENSGALT00000043009; ENSGALP00000041673; ENSGALG00000028265.
GeneIDi374273.
KEGGigga:374273.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB050010 mRNA. Translation: BAC65172.1.
RefSeqiNP_989686.1. NM_204355.1.
UniGeneiGga.9460.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000005035.

Proteomic databases

PaxDbiQ800K9.
PRIDEiQ800K9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000043009; ENSGALP00000041673; ENSGALG00000028265.
GeneIDi374273.
KEGGigga:374273.

Organism-specific databases

CTDi6836.

Phylogenomic databases

eggNOGiKOG3998. Eukaryota.
COG2259. LUCA.
GeneTreeiENSGT00530000064123.
HOGENOMiHOG000206959.
HOVERGENiHBG054238.
InParanoidiQ800K9.
OMAiDQLWYLQ.
OrthoDBiEOG091G0H3P.
PhylomeDBiQ800K9.
TreeFamiTF300001.

Enzyme and pathway databases

ReactomeiR-GGA-6811434. COPI-dependent Golgi-to-ER retrograde traffic.

Miscellaneous databases

PROiQ800K9.

Gene expression databases

BgeeiENSGALG00000028265.

Family and domain databases

InterProiIPR002995. Surf4.
[Graphical view]
PfamiPF02077. SURF4. 1 hit.
[Graphical view]
PROSITEiPS01339. SURF4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSURF4_CHICK
AccessioniPrimary (citable) accession number: Q800K9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.