Q7ZYY4 (FAM3C_DANRE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein FAM3C

Gene names

Name:	fam3c
ORF Names:	si:dkey-159a18.2

Organism

Danio rerio (Zebrafish) (Brachydanio rerio)

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	227 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Involved in retinal laminar formation By similarity.
Subcellular location	Secreted By similarity.
Sequence similarities	Belongs to the FAM3 family.
Sequence caution	The sequence AAH66710.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
Molecular function	Developmental protein
PTM	Disulfide bond
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 30	30	Potential
	Chain	31 – 227	197	Protein FAM3C		PRO_0000395983
Amino acid modifications
	Disulfide bond	58 ↔ 221		Potential
	Disulfide bond	64 ↔ 86		Potential

Sequences

	Sequence		Length	Mass (Da)
	Q7ZYY4 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 4999A0F191A292C1	FASTA	227	24,921
	10 20 30 40 50 60 MMRAGGLLKL GVLVSVLFVA VFLAFELLES NMNFNLGKVF TRYAPPDAVP TRPLRHKCGL 70 80 90 100 110 120 SKSCPEDHFA FKITSGAASV VGPKMCFQDN VIMSGVKNNI GRGINIALLN GKTGELTKTD 130 140 150 160 170 180 SFDMWTGDVN LLIKFLKDIE DGSIVMMATF DDPATKMNDE ARNLIADLGS SSISILGFRD 190 200 210 220 NWVFVGGKGI KTKSPFEQHI KNNAETNKYE GWPEVLEMEG CIPIKHD

References

[1]	The Danio rerio sequencing project at the Sanger Institute Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen.
[2]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: AB. Tissue: Kidney.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX890616 Genomic DNA. Translation: CAI20694.1. BC044170 mRNA. Translation: AAH44170.1. BC066710 mRNA. Translation: AAH66710.1. Different initiation.
IPI	IPI00485989.
RefSeq	NP_997890.1. NM_212725.1.
UniGene	Dr.77795.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q7ZYY4.
Proteomic databases
PRIDE	Q7ZYY4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000100867; ENSDARP00000091640; ENSDARG00000056152.
GeneID	334205.
KEGG	dre:334205.
Organism-specific databases
CTD	10447.
ZFIN	ZDB-GENE-030131-6137. fam3c.
Phylogenomic databases
GeneTree	ENSGT00530000063020.
HOGENOM	HBG714462.
OMA	CGLSKAC.
OrthoDB	EOG43R3NW.
Gene expression databases
ArrayExpress	Q7ZYY4.
Bgee	Q7ZYY4.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

FAM3C_DANRE

Accession

Primary (citable) accession number: Q7ZYY4
Secondary accession number(s): Q6NY75

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 10, 2010
Last sequence update:	June 1, 2003
Last modified:	September 21, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program