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Protein

Alkaline phosphatase

Gene

alpl

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Alkaline phosphataseUniRule annotation (EC:3.1.3.1UniRule annotation)
Gene namesi
Name:alplImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-1010304. alpl.

PTM / Processingi

Keywords - PTMi

PhosphoproteinUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ7ZYJ4.
SMRiQ7ZYJ4. Positions 20-490.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alkaline phosphatase family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG007345.
KOiK01077.

Family and domain databases

Gene3Di3.40.720.10. 1 hit.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR001952. Alkaline_phosphatase.
IPR018299. Alkaline_phosphatase_AS.
IPR017850. Alkaline_phosphatase_core.
[Graphical view]
PfamiPF00245. Alk_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00113. ALKPHPHTASE.
SMARTiSM00098. alkPPc. 1 hit.
[Graphical view]
SUPFAMiSSF53649. SSF53649. 1 hit.
PROSITEiPS00123. ALKALINE_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7ZYJ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKLWLLLLL GTLSESVTFP EQEKNPNYWR RQAQETLMNA LQLQNLNTNV
60 70 80 90 100
AKNVIMFLGD GMGVPTVTAA RILKGQLAGQ PGEETQLEMD KFPHVALSKT
110 120 130 140 150
YNTNAQVPDS AGTATAYLCG VKANEGTVGV NAAAVRNQCN TSKGNEVDSI
160 170 180 190 200
MKWAKQAGKS VGVVTTTRIN HATPSAAYAH CVNRDWYSDQ EMPKEAVEQG
210 220 230 240 250
CKDIAWQLMN NIPNIEVIMG GGRKYMFPKN TSDVEYPNDD KSSGTRLDGL
260 270 280 290 300
NLTQIWLDQK PNKKAARYVW NREQLLSVNP QEVDHLLGLF EPVDMLYDLE
310 320 330 340 350
RNTTMDPSLS EMVEAAIKIL GKNPMGFFLL VEGGRIDHGH HEGKANQALH
360 370 380 390 400
EAVQMDIAIG VSGNMTSVED TLTVVTADHS HVFTFGGYTH RGNPIFGLAP
410 420 430 440 450
VPSDVDQKPF TSILYGNGPG YKLVNGQREN VSTVDFSHPN YLAQSAVPLR
460 470 480 490 500
METHGGEDVA VFAKGPMAHL LHGVHEQNYI PHVMAYASCI GQNQDHCTSG
510 520
KGNNGARTSL ILVSVLLPLF SLQLFY
Length:526
Mass (Da):57,677
Last modified:June 1, 2003 - v1
Checksum:i28C643D566FD6911
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC043760 mRNA. Translation: AAH43760.1.
RefSeqiNP_001080895.1. NM_001087426.1.
UniGeneiXl.1299.

Genome annotation databases

GeneIDi380589.
KEGGixla:380589.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC043760 mRNA. Translation: AAH43760.1.
RefSeqiNP_001080895.1. NM_001087426.1.
UniGeneiXl.1299.

3D structure databases

ProteinModelPortaliQ7ZYJ4.
SMRiQ7ZYJ4. Positions 20-490.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi380589.
KEGGixla:380589.

Organism-specific databases

CTDi249.
XenbaseiXB-GENE-1010304. alpl.

Phylogenomic databases

HOVERGENiHBG007345.
KOiK01077.

Family and domain databases

Gene3Di3.40.720.10. 1 hit.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR001952. Alkaline_phosphatase.
IPR018299. Alkaline_phosphatase_AS.
IPR017850. Alkaline_phosphatase_core.
[Graphical view]
PfamiPF00245. Alk_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00113. ALKPHPHTASE.
SMARTiSM00098. alkPPc. 1 hit.
[Graphical view]
SUPFAMiSSF53649. SSF53649. 1 hit.
PROSITEiPS00123. ALKALINE_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EmbryoImported.

Entry informationi

Entry nameiQ7ZYJ4_XENLA
AccessioniPrimary (citable) accession number: Q7ZYJ4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: July 22, 2015
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.