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Protein

Alkaline phosphatase

Gene

alpl

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMagnesiumUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Alkaline phosphataseUniRule annotation (EC:3.1.3.1UniRule annotation)
Gene namesi
Name:alplImported
ORF Names:XELAEV_18036350mgImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus
Proteomesi
  • UP000186698 Componenti: Chromosome 7l

Organism-specific databases

XenbaseiXB-GENE-1010304. alpl.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_501050893717 – 526Alkaline phosphataseSequence analysisAdd BLAST510

Family & Domainsi

Sequence similaritiesi

Belongs to the alkaline phosphatase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

HOVERGENiHBG007345.
KOiK01077.

Family and domain databases

CDDicd16012. ALP. 1 hit.
Gene3Di3.40.720.10. 1 hit.
InterProiView protein in InterPro
IPR017849. Alkaline_Pase-like_a/b/a.
IPR001952. Alkaline_phosphatase.
IPR018299. Alkaline_phosphatase_AS.
IPR017850. Alkaline_phosphatase_core.
PANTHERiPTHR11596. PTHR11596. 1 hit.
PfamiView protein in Pfam
PF00245. Alk_phosphatase. 1 hit.
PRINTSiPR00113. ALKPHPHTASE.
SMARTiView protein in SMART
SM00098. alkPPc. 1 hit.
SUPFAMiSSF53649. SSF53649. 1 hit.
PROSITEiView protein in PROSITE
PS00123. ALKALINE_PHOSPHATASE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7ZYJ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKLWLLLLL GTLSESVTFP EQEKNPNYWR RQAQETLMNA LQLQNLNTNV
60 70 80 90 100
AKNVIMFLGD GMGVPTVTAA RILKGQLAGQ PGEETQLEMD KFPHVALSKT
110 120 130 140 150
YNTNAQVPDS AGTATAYLCG VKANEGTVGV NAAAVRNQCN TSKGNEVDSI
160 170 180 190 200
MKWAKQAGKS VGVVTTTRIN HATPSAAYAH CVNRDWYSDQ EMPKEAVEQG
210 220 230 240 250
CKDIAWQLMN NIPNIEVIMG GGRKYMFPKN TSDVEYPNDD KSSGTRLDGL
260 270 280 290 300
NLTQIWLDQK PNKKAARYVW NREQLLSVNP QEVDHLLGLF EPVDMLYDLE
310 320 330 340 350
RNTTMDPSLS EMVEAAIKIL GKNPMGFFLL VEGGRIDHGH HEGKANQALH
360 370 380 390 400
EAVQMDIAIG VSGNMTSVED TLTVVTADHS HVFTFGGYTH RGNPIFGLAP
410 420 430 440 450
VPSDVDQKPF TSILYGNGPG YKLVNGQREN VSTVDFSHPN YLAQSAVPLR
460 470 480 490 500
METHGGEDVA VFAKGPMAHL LHGVHEQNYI PHVMAYASCI GQNQDHCTSG
510 520
KGNNGARTSL ILVSVLLPLF SLQLFY
Length:526
Mass (Da):57,677
Last modified:June 1, 2003 - v1
Checksum:i28C643D566FD6911
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC043760 mRNA. Translation: AAH43760.1.
CM004478 Genomic DNA. Translation: OCT73367.1.
RefSeqiNP_001080895.1. NM_001087426.1.
UniGeneiXl.1299.

Genome annotation databases

GeneIDi380589.
KEGGixla:380589.

Similar proteinsi

Entry informationi

Entry nameiQ7ZYJ4_XENLA
AccessioniPrimary (citable) accession number: Q7ZYJ4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: August 30, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported