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Q7ZY08 (UBE2T_XENLA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ubiquitin-conjugating enzyme E2 T

EC=6.3.2.19
Alternative name(s):
Ubiquitin carrier protein T
Ubiquitin-protein ligase T
Gene names
Name:ube2t
OrganismXenopus laevis (African clawed frog)
Taxonomic identifier8355 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Protein attributes

Sequence length192 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in DNA repair By similarity.

Catalytic activity

ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.

Pathway

Protein modification; protein ubiquitination.

Subcellular location

Nucleus By similarity. Note: Accumulates to chromatin By similarity.

Sequence similarities

Belongs to the ubiquitin-conjugating enzyme family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 192192Ubiquitin-conjugating enzyme E2 T
PRO_0000082511

Sites

Active site861Glycyl thioester intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7ZY08 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 47214E394A77983E

FASTA19221,554
        10         20         30         40         50         60 
MQRVSRLKRE LQLLNKEPPP GVICWQNESN MDDLRAQIIG GSGSPYEGGI FNLEIIVPER 

        70         80         90        100        110        120 
YPFEPPKIRF LTPIYHPNID SAGRICLDIL KLPPKGAWRP ALNISTVLTS IQLLMSEPNP 

       130        140        150        160        170        180 
DDPLMADISS EFKYNRAVFF SNAKKWTEKH ALPAPQGSDK ESQEKSGSSE GTSHKRKSAE 

       190 
IAEESKKPCR EP 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Embryo.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC044029 mRNA. Translation: AAH44029.1.
RefSeqNP_001080105.1. NM_001086636.1.
UniGeneXl.12282.

3D structure databases

ProteinModelPortalQ7ZY08.
SMRQ7ZY08. Positions 1-151.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ7ZY08.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID379797.
KEGGxla:379797.

Organism-specific databases

CTD29089.
XenbaseXB-GENE-6254937. ube2t.

Phylogenomic databases

HOVERGENHBG063308.
KOK13960.

Enzyme and pathway databases

UniPathwayUPA00143.

Family and domain databases

Gene3D3.10.110.10. 1 hit.
InterProIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMSSF54495. SSF54495. 1 hit.
PROSITEPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUBE2T_XENLA
AccessionPrimary (citable) accession number: Q7ZY08
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: June 1, 2003
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways