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Protein
Submitted name:

Capn1 protein

Gene

capn1

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol proteaseSAAS annotation

Protein family/group databases

MEROPSiC02.001.

Names & Taxonomyi

Protein namesi
Submitted name:
Capn1 proteinImported
Gene namesi
Name:capn1Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-6540652. capn1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliQ7ZXQ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 354Calpain catalyticInterPro annotationAdd BLAST300
Domaini557 – 575EF-handInterPro annotationAdd BLAST19
Domaini584 – 609EF-handInterPro annotationAdd BLAST26
Domaini614 – 649EF-handInterPro annotationAdd BLAST36

Sequence similaritiesi

Belongs to the peptidase C2 family.SAAS annotation

Phylogenomic databases

HOVERGENiHBG012645.
KOiK01367.

Family and domain databases

CDDicd00214. Calpain_III. 1 hit.
cd00044. CysPc. 1 hit.
cd00051. EFh. 1 hit.
Gene3Di1.10.238.10. 1 hit.
InterProiIPR033883. C2_III.
IPR022684. Calpain_cysteine_protease.
IPR022682. Calpain_domain_III.
IPR022683. Calpain_III.
IPR029643. CAPN1.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000169. Pept_cys_AS.
IPR001300. Peptidase_C2_calpain_cat.
[Graphical view]
PANTHERiPTHR10183:SF284. PTHR10183:SF284. 1 hit.
PfamiPF01067. Calpain_III. 1 hit.
PF13833. EF-hand_8. 1 hit.
PF00648. Peptidase_C2. 1 hit.
[Graphical view]
PRINTSiPR00704. CALPAIN.
SMARTiSM00720. calpain_III. 1 hit.
SM00230. CysPc. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
SSF49758. SSF49758. 1 hit.
PROSITEiPS50203. CALPAIN_CAT. 1 hit.
PS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 3 hits.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7ZXQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEEVIVPVY ATGISAQLQK QRDQDLGVGK HENAVKFLGQ DYDRIRHECL
60 70 80 90 100
QNGTLFKDDT FPASAYSLGF KELGPNSSKT YGVKWVRPSQ LVSNPQFIVD
110 120 130 140 150
GATRTDICQG ALGDCWLLAA IASLTLNETV LHRVVPHGQS FQENYAGVFH
160 170 180 190 200
FQLWQFGEWV DVVIDDLLPV KDGKLVFVHS ASGNEFWSAL LEKAYAKANG
210 220 230 240 250
CYEALSGGST SEGFEDFTGG VTEWYEMKKA PKDLFNIILK ALERGSLMGC
260 270 280 290 300
SIDITSATDM EAVTFKKLVK GHAYSVTGAK EINFRGQNTK LIRMRNPWGE
310 320 330 340 350
VEWTGAWSDN SSEWNYVGQA DSNELRIKME DGEFWMSFED FLREFSRLEI
360 370 380 390 400
CNLTPDALTA RRYRKWNTTV YNGSWRKGST AGGCRNFPAT FWINPQFKIK
410 420 430 440 450
LEEEDGDDDY GSETGCTFLL ALMQKNKRKE RRFGKDMETI GFAVYEVPRE
460 470 480 490 500
FLGQSGVHLK RDFFLQNASR ARSEQFINLR EVSTRHKLPP GEYIVVPSTF
510 520 530 540 550
EPNVEGDFVI RVFSENKHGS VEMDDPLSAD LPPEEVLSET EIDQGFKNLF
560 570 580 590 600
KQLAGADMEI SYTELQSILN KIVSKHKDLR TTGFSLESCR SMVNLMDKDG
610 620 630 640 650
NGKLGLVEFN ILWNKIKNYL TIFRKFDMDK SGSMSAYEMR LALESAGFKL
660 670 680 690 700
TNSLHQLIIT RYSEPDMAVN FDSFTCCLIR LETMFRFFQG MDTQKQGVIN
710
FDLFSWLQMT MFA
Length:713
Mass (Da):81,008
Last modified:June 1, 2003 - v1
Checksum:iDC4B7CFEB7F884BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC044317 mRNA. Translation: AAH44317.1.
RefSeqiNP_001080485.1. NM_001087016.1.
UniGeneiXl.3776.

Genome annotation databases

GeneIDi380177.
KEGGixla:380177.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC044317 mRNA. Translation: AAH44317.1.
RefSeqiNP_001080485.1. NM_001087016.1.
UniGeneiXl.3776.

3D structure databases

ProteinModelPortaliQ7ZXQ4.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiC02.001.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi380177.
KEGGixla:380177.

Organism-specific databases

CTDi823.
XenbaseiXB-GENE-6540652. capn1.

Phylogenomic databases

HOVERGENiHBG012645.
KOiK01367.

Family and domain databases

CDDicd00214. Calpain_III. 1 hit.
cd00044. CysPc. 1 hit.
cd00051. EFh. 1 hit.
Gene3Di1.10.238.10. 1 hit.
InterProiIPR033883. C2_III.
IPR022684. Calpain_cysteine_protease.
IPR022682. Calpain_domain_III.
IPR022683. Calpain_III.
IPR029643. CAPN1.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000169. Pept_cys_AS.
IPR001300. Peptidase_C2_calpain_cat.
[Graphical view]
PANTHERiPTHR10183:SF284. PTHR10183:SF284. 1 hit.
PfamiPF01067. Calpain_III. 1 hit.
PF13833. EF-hand_8. 1 hit.
PF00648. Peptidase_C2. 1 hit.
[Graphical view]
PRINTSiPR00704. CALPAIN.
SMARTiSM00720. calpain_III. 1 hit.
SM00230. CysPc. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
SSF49758. SSF49758. 1 hit.
PROSITEiPS50203. CALPAIN_CAT. 1 hit.
PS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 3 hits.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ7ZXQ4_XENLA
AccessioniPrimary (citable) accession number: Q7ZXQ4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: November 30, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.