Q7ZXH3 (TAB3_XENLA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 homolog

Gene names

Name:

map3k7ip3

Organism

Xenopus laevis (African clawed frog)

Taxonomic identifier

8355 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length	692 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May play a role in signaling pathway.
Sequence similarities	Contains 1 CUE domain. Contains 1 RanBP2-type zinc finger.

Ontologies

Keywords
Domain	Coiled coil Zinc-finger
Ligand	Metal-binding Zinc
Gene Ontology (GO)
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 692	692	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 homolog		PRO_0000226974
Regions
	Domain	8 – 51	44	CUE
	Zinc finger	662 – 692	31	RanBP2-type
	Coiled coil	496 – 580	85	Potential
	Compositional bias	145 – 321	177	Pro-rich
	Compositional bias	483 – 488	6	Poly-Ser

Sequences

	Sequence		Length	Mass (Da)
	Q7ZXH3 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 399363038A86046A	FASTA	692	76,708
	10 20 30 40 50 60 MAQSSPQLDI QVLNDLQQRF PEIPRDVVSQ CMLQNNSNLD ACYRALTQES CKYLYMDYHN 70 80 90 100 110 120 LDETRMNSNL LHINLGIHPS STYHTGDGAQ VNGRPLVHSS SDGHIDPQRS PGKLLCLVPE 130 140 150 160 170 180 PQSAPAVVAQ NYNQFFLNDQ NRNSPTPPPQ PVQQPGVGTS AMQASLPTYM HVPRYSANPI 190 200 210 220 230 240 TVTVSPSGHN VPRALQIVPQ VQNNPYGTPI YIRHPSQNSP GRQTQQNTAW PPSPQAVLPH 250 260 270 280 290 300 YNPCPPYPQS FQPTQYSPKQ PQIPQSAFRS PPTSQCTSPY SSPQHQVQTN QLSHQTSHVF 310 320 330 340 350 360 LPPSPSTVSP HLYQQAPPPY PKQSSLGYLP YGPGLNKGPM NKIEITVESQ QRPGPTLNRS 370 380 390 400 410 420 PSPINNQSAQ RSQQHPVYVS NARSGSPSRG IPTQPKASYS GSPLFITYSQ PPTTTGSPTP 430 440 450 460 470 480 SSRVVMSPSN PTVFKITVGR APTENLLNIV DQEQHPSTPE PIQPISLLPV SGGDKGIHKY 490 500 510 520 530 540 HRSSSSGSDD YAYTQALLLH QRARMERLAK ELKHEKEELE RLKAEVNGME HDLMQRRLRR 550 560 570 580 590 600 VSCTTAIPTP EEMTRLRGLN RQLQINVDCT QKEIDLLQSR GMAKLDVKAM SNFYDNLSPG 610 620 630 640 650 660 PAVPPNTCKK ESSETTSGER KARRISVTSK IKSDPPDLQA PSSLDIGPWQ RASPRPGRDE 670 680 690 DFEGSPWNCN SCTFLNHPAL NRCEQCEMPR FT

References

[1]	NIH - Xenopus Gene Collection (XGC) project Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Embryo.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC044992 mRNA. Translation: AAH44992.1.
RefSeq	NP_001079583.1. NM_001086114.1.
UniGene	Xl.6680.
3D structure databases
ProteinModelPortal	Q7ZXH3.
SMR	Q7ZXH3. Positions 4-55.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	379270.
KEGG	xla:379270.
Organism-specific databases
CTD	379270.
Xenbase	XB-GENE-942655. tab3.
Phylogenomic databases
HOVERGEN	HBG056952.
Family and domain databases
InterPro	IPR003892. CUE. IPR001876. Znf_RanBP2. [Graphical view]
KO	K12793.
Pfam	PF02845. CUE. 1 hit. [Graphical view]
SMART	SM00547. ZnF_RBZ. 1 hit. [Graphical view]
PROSITE	PS51140. CUE. 1 hit. PS01358. ZF_RANBP2_1. 1 hit. PS50199. ZF_RANBP2_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAB3_XENLA

Accession

Primary (citable) accession number: Q7ZXH3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 7, 2006
Last sequence update:	June 1, 2003
Last modified:	November 16, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program