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Q7ZXF4

- Q7ZXF4_XENLA

UniProt

Q7ZXF4 - Q7ZXF4_XENLA

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Protein
Submitted name:

Mthfd1-prov protein

Gene

mthfd1

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. formate-tetrahydrofolate ligase activity Source: InterPro
  3. methylenetetrahydrofolate dehydrogenase (NADP+) activity Source: InterPro

GO - Biological processi

  1. folic acid-containing compound biosynthetic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Mthfd1-prov proteinImported
Gene namesi
Name:mthfd1Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-992138. mthfd1.

PTM / Processingi

Proteomic databases

PRIDEiQ7ZXF4.

Structurei

3D structure databases

ProteinModelPortaliQ7ZXF4.
SMRiQ7ZXF4. Positions 2-294, 468-530.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG004916.
KOiK00288.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
3.40.50.720. 1 hit.
HAMAPiMF_01543. FTHFS.
MF_01576. THF_DHG_CYH.
InterProiIPR000559. Formate_THF_ligase.
IPR020628. Formate_THF_ligase_CS.
IPR016040. NAD(P)-bd_dom.
IPR027417. P-loop_NTPase.
IPR000672. THF_DH/CycHdrlase.
IPR020630. THF_DH/CycHdrlase_cat_dom.
IPR020867. THF_DH/CycHdrlase_CS.
IPR020631. THF_DH/CycHdrlase_NAD-bd_dom.
[Graphical view]
PfamiPF01268. FTHFS. 1 hit.
PF00763. THF_DHG_CYH. 1 hit.
PF02882. THF_DHG_CYH_C. 1 hit.
[Graphical view]
PRINTSiPR00085. THFDHDRGNASE.
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00721. FTHFS_1. 1 hit.
PS00722. FTHFS_2. 1 hit.
PS00766. THF_DHG_CYH_1. 1 hit.
PS00767. THF_DHG_CYH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7ZXF4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPAEILSGKV VSGLVRERLK TEVAAMKEKV PGFSPGLAIV QVGDRDDSNL
60 70 80 90 100
YISMKLKAAA EIGISASHVK LPKTATEAEV LSKIMSINED PAYHGMIVQL
110 120 130 140 150
PLDSDHPINT EKVTNAVSPA KDVDGLTSIN AGKLARGDLG DCFIPCTPKG
160 170 180 190 200
CMDLIKQTGV QIPGKRAVVI GRSKIVGAPM HDLLLWNHAT VTTCHSKTAS
210 220 230 240 250
LNEEVSRADI LVVGAGKPEM VKGDWIKPGA IVIDCGINYV PDPNKPSGKR
260 270 280 290 300
VVGDVAYVEA KEKASYITPV PGGVGPMTVA MLMENTVESA KRYLVQFQPH
310 320 330 340 350
KWNIEYNKLH LKVPVPSDIE ISRSCIPKPI AKISEEIGLL SQEVELYGQT
360 370 380 390 400
KAKVLLSTLK RLQNREDGKY VVVTGITPTP LGEGKSTTTI GLVQALGAHL
410 420 430 440 450
NLNVFACVRQ PSQGPTFGIK GGAAGGGYSQ VIPMEEFNLH LTGDIHAITA
460 470 480 490 500
ANNLVAAAID ARIFHELTQS DKALYSRLVP SNNGVRKFSD IQIRRLRRLG
510 520 530 540 550
IEKTDPAALT EEEINKFVRL DIDPDTITWQ RVLDTNDRFL RKITIGQAPT
560 570 580 590 600
EKGFTRTAQF DISVASEIMA VLALTDGLDN MRERLGKMVV ASSKKGEPVS
610 620 630 640 650
TEDLGVSGAL TVLMKDAVKP NLMQTMEGNP VFVHAGPFAN IAHGNSSILA
660 670 680 690 700
DKIALKLVGP EGFVVTEAGF GADIGMEKFF NIKCRYSGLR PHVVVLVSTV
710 720 730 740 750
RALKMHGGGP TVTAGVPLPK EYTEENLDLI EKGCSNLRKQ IENATIFGVP
760 770 780 790 800
VVVAVNAFKT DTEAELDIVC DLAKKAGAFD AIRCTHWADG GKGAVALAQA
810 820 830 840 850
VQRASQAPSN FKFLYDVQLP IADKIRIIAQ KIYGADDIEL LPEAQKKADL
860 870 880 890 900
YTKQGFGNLP VCMAKTHLSL SHNPELKGVP TGFVLPIRDI RASVGAGFLY
910 920 930
PLVGTMSTMP GLPTRPCFYD IDLDPVSEQV NGLF
Length:934
Mass (Da):100,549
Last modified:June 1, 2003 - v1
Checksum:iB0DCDA5CA5E4824C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC045019 mRNA. Translation: AAH45019.1.
RefSeqiNP_001080574.1. NM_001087105.1.
UniGeneiXl.3693.

Genome annotation databases

GeneIDi380266.
KEGGixla:380266.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC045019 mRNA. Translation: AAH45019.1 .
RefSeqi NP_001080574.1. NM_001087105.1.
UniGenei Xl.3693.

3D structure databases

ProteinModelPortali Q7ZXF4.
SMRi Q7ZXF4. Positions 2-294, 468-530.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q7ZXF4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 380266.
KEGGi xla:380266.

Organism-specific databases

CTDi 4522.
Xenbasei XB-GENE-992138. mthfd1.

Phylogenomic databases

HOVERGENi HBG004916.
KOi K00288.

Family and domain databases

Gene3Di 3.40.50.300. 2 hits.
3.40.50.720. 1 hit.
HAMAPi MF_01543. FTHFS.
MF_01576. THF_DHG_CYH.
InterProi IPR000559. Formate_THF_ligase.
IPR020628. Formate_THF_ligase_CS.
IPR016040. NAD(P)-bd_dom.
IPR027417. P-loop_NTPase.
IPR000672. THF_DH/CycHdrlase.
IPR020630. THF_DH/CycHdrlase_cat_dom.
IPR020867. THF_DH/CycHdrlase_CS.
IPR020631. THF_DH/CycHdrlase_NAD-bd_dom.
[Graphical view ]
Pfami PF01268. FTHFS. 1 hit.
PF00763. THF_DHG_CYH. 1 hit.
PF02882. THF_DHG_CYH_C. 1 hit.
[Graphical view ]
PRINTSi PR00085. THFDHDRGNASE.
SUPFAMi SSF52540. SSF52540. 2 hits.
PROSITEi PS00721. FTHFS_1. 1 hit.
PS00722. FTHFS_2. 1 hit.
PS00766. THF_DHG_CYH_1. 1 hit.
PS00767. THF_DHG_CYH_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EmbryoImported.

Entry informationi

Entry nameiQ7ZXF4_XENLA
AccessioniPrimary (citable) accession number: Q7ZXF4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: October 1, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)