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Protein
Submitted name:

Mthfd1-prov protein

Gene

mthfd1

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Mthfd1-prov proteinImported
Gene namesi
Name:mthfd1Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-992138. mthfd1.

PTM / Processingi

Proteomic databases

PRIDEiQ7ZXF4.

Structurei

3D structure databases

ProteinModelPortaliQ7ZXF4.
SMRiQ7ZXF4. Positions 2-294, 468-530.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG004916.
KOiK00288.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
3.40.50.720. 1 hit.
HAMAPiMF_01543. FTHFS.
MF_01576. THF_DHG_CYH.
InterProiIPR000559. Formate_THF_ligase.
IPR020628. Formate_THF_ligase_CS.
IPR016040. NAD(P)-bd_dom.
IPR027417. P-loop_NTPase.
IPR000672. THF_DH/CycHdrlase.
IPR020630. THF_DH/CycHdrlase_cat_dom.
IPR020867. THF_DH/CycHdrlase_CS.
IPR020631. THF_DH/CycHdrlase_NAD-bd_dom.
[Graphical view]
PfamiPF01268. FTHFS. 1 hit.
PF00763. THF_DHG_CYH. 1 hit.
PF02882. THF_DHG_CYH_C. 1 hit.
[Graphical view]
PRINTSiPR00085. THFDHDRGNASE.
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00721. FTHFS_1. 1 hit.
PS00722. FTHFS_2. 1 hit.
PS00766. THF_DHG_CYH_1. 1 hit.
PS00767. THF_DHG_CYH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7ZXF4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAEILSGKV VSGLVRERLK TEVAAMKEKV PGFSPGLAIV QVGDRDDSNL
60 70 80 90 100
YISMKLKAAA EIGISASHVK LPKTATEAEV LSKIMSINED PAYHGMIVQL
110 120 130 140 150
PLDSDHPINT EKVTNAVSPA KDVDGLTSIN AGKLARGDLG DCFIPCTPKG
160 170 180 190 200
CMDLIKQTGV QIPGKRAVVI GRSKIVGAPM HDLLLWNHAT VTTCHSKTAS
210 220 230 240 250
LNEEVSRADI LVVGAGKPEM VKGDWIKPGA IVIDCGINYV PDPNKPSGKR
260 270 280 290 300
VVGDVAYVEA KEKASYITPV PGGVGPMTVA MLMENTVESA KRYLVQFQPH
310 320 330 340 350
KWNIEYNKLH LKVPVPSDIE ISRSCIPKPI AKISEEIGLL SQEVELYGQT
360 370 380 390 400
KAKVLLSTLK RLQNREDGKY VVVTGITPTP LGEGKSTTTI GLVQALGAHL
410 420 430 440 450
NLNVFACVRQ PSQGPTFGIK GGAAGGGYSQ VIPMEEFNLH LTGDIHAITA
460 470 480 490 500
ANNLVAAAID ARIFHELTQS DKALYSRLVP SNNGVRKFSD IQIRRLRRLG
510 520 530 540 550
IEKTDPAALT EEEINKFVRL DIDPDTITWQ RVLDTNDRFL RKITIGQAPT
560 570 580 590 600
EKGFTRTAQF DISVASEIMA VLALTDGLDN MRERLGKMVV ASSKKGEPVS
610 620 630 640 650
TEDLGVSGAL TVLMKDAVKP NLMQTMEGNP VFVHAGPFAN IAHGNSSILA
660 670 680 690 700
DKIALKLVGP EGFVVTEAGF GADIGMEKFF NIKCRYSGLR PHVVVLVSTV
710 720 730 740 750
RALKMHGGGP TVTAGVPLPK EYTEENLDLI EKGCSNLRKQ IENATIFGVP
760 770 780 790 800
VVVAVNAFKT DTEAELDIVC DLAKKAGAFD AIRCTHWADG GKGAVALAQA
810 820 830 840 850
VQRASQAPSN FKFLYDVQLP IADKIRIIAQ KIYGADDIEL LPEAQKKADL
860 870 880 890 900
YTKQGFGNLP VCMAKTHLSL SHNPELKGVP TGFVLPIRDI RASVGAGFLY
910 920 930
PLVGTMSTMP GLPTRPCFYD IDLDPVSEQV NGLF
Length:934
Mass (Da):100,549
Last modified:June 1, 2003 - v1
Checksum:iB0DCDA5CA5E4824C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC045019 mRNA. Translation: AAH45019.1.
RefSeqiNP_001080574.1. NM_001087105.1.
UniGeneiXl.3693.

Genome annotation databases

GeneIDi380266.
KEGGixla:380266.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC045019 mRNA. Translation: AAH45019.1.
RefSeqiNP_001080574.1. NM_001087105.1.
UniGeneiXl.3693.

3D structure databases

ProteinModelPortaliQ7ZXF4.
SMRiQ7ZXF4. Positions 2-294, 468-530.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ7ZXF4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi380266.
KEGGixla:380266.

Organism-specific databases

CTDi4522.
XenbaseiXB-GENE-992138. mthfd1.

Phylogenomic databases

HOVERGENiHBG004916.
KOiK00288.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
3.40.50.720. 1 hit.
HAMAPiMF_01543. FTHFS.
MF_01576. THF_DHG_CYH.
InterProiIPR000559. Formate_THF_ligase.
IPR020628. Formate_THF_ligase_CS.
IPR016040. NAD(P)-bd_dom.
IPR027417. P-loop_NTPase.
IPR000672. THF_DH/CycHdrlase.
IPR020630. THF_DH/CycHdrlase_cat_dom.
IPR020867. THF_DH/CycHdrlase_CS.
IPR020631. THF_DH/CycHdrlase_NAD-bd_dom.
[Graphical view]
PfamiPF01268. FTHFS. 1 hit.
PF00763. THF_DHG_CYH. 1 hit.
PF02882. THF_DHG_CYH_C. 1 hit.
[Graphical view]
PRINTSiPR00085. THFDHDRGNASE.
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00721. FTHFS_1. 1 hit.
PS00722. FTHFS_2. 1 hit.
PS00766. THF_DHG_CYH_1. 1 hit.
PS00767. THF_DHG_CYH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EmbryoImported.

Entry informationi

Entry nameiQ7ZXF4_XENLA
AccessioniPrimary (citable) accession number: Q7ZXF4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: July 22, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.