Q7ZXF4 (Q7ZXF4_XENLA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Mthfd1-prov protein EMBL AAH45019.1

Gene names

Name:

mthfd1 Xenbase XB-GENE-992138

Organism

Xenopus laevis (African clawed frog) EMBL AAH45019.1

Taxonomic identifier

8355 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length	934 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	folic acid-containing compound biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro formate-tetrahydrofolate ligase activity Inferred from electronic annotation. Source: InterPro methylenetetrahydrofolate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7ZXF4 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: B0DCDA5CA5E4824C	FASTA	934	100,549
	10 20 30 40 50 60 MPAEILSGKV VSGLVRERLK TEVAAMKEKV PGFSPGLAIV QVGDRDDSNL YISMKLKAAA 70 80 90 100 110 120 EIGISASHVK LPKTATEAEV LSKIMSINED PAYHGMIVQL PLDSDHPINT EKVTNAVSPA 130 140 150 160 170 180 KDVDGLTSIN AGKLARGDLG DCFIPCTPKG CMDLIKQTGV QIPGKRAVVI GRSKIVGAPM 190 200 210 220 230 240 HDLLLWNHAT VTTCHSKTAS LNEEVSRADI LVVGAGKPEM VKGDWIKPGA IVIDCGINYV 250 260 270 280 290 300 PDPNKPSGKR VVGDVAYVEA KEKASYITPV PGGVGPMTVA MLMENTVESA KRYLVQFQPH 310 320 330 340 350 360 KWNIEYNKLH LKVPVPSDIE ISRSCIPKPI AKISEEIGLL SQEVELYGQT KAKVLLSTLK 370 380 390 400 410 420 RLQNREDGKY VVVTGITPTP LGEGKSTTTI GLVQALGAHL NLNVFACVRQ PSQGPTFGIK 430 440 450 460 470 480 GGAAGGGYSQ VIPMEEFNLH LTGDIHAITA ANNLVAAAID ARIFHELTQS DKALYSRLVP 490 500 510 520 530 540 SNNGVRKFSD IQIRRLRRLG IEKTDPAALT EEEINKFVRL DIDPDTITWQ RVLDTNDRFL 550 560 570 580 590 600 RKITIGQAPT EKGFTRTAQF DISVASEIMA VLALTDGLDN MRERLGKMVV ASSKKGEPVS 610 620 630 640 650 660 TEDLGVSGAL TVLMKDAVKP NLMQTMEGNP VFVHAGPFAN IAHGNSSILA DKIALKLVGP 670 680 690 700 710 720 EGFVVTEAGF GADIGMEKFF NIKCRYSGLR PHVVVLVSTV RALKMHGGGP TVTAGVPLPK 730 740 750 760 770 780 EYTEENLDLI EKGCSNLRKQ IENATIFGVP VVVAVNAFKT DTEAELDIVC DLAKKAGAFD 790 800 810 820 830 840 AIRCTHWADG GKGAVALAQA VQRASQAPSN FKFLYDVQLP IADKIRIIAQ KIYGADDIEL 850 860 870 880 890 900 LPEAQKKADL YTKQGFGNLP VCMAKTHLSL SHNPELKGVP TGFVLPIRDI RASVGAGFLY 910 920 930 PLVGTMSTMP GLPTRPCFYD IDLDPVSEQV NGLF

References

[1]	NIH - Xenopus Gene Collection (XGC) project Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Embryo EMBL AAH45019.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC045019 mRNA. Translation: AAH45019.1.
RefSeq	NP_001080574.1. NM_001087105.1.
UniGene	Xl.3693.
3D structure databases
HSSP	HSSP built from PDB template 1A4I based on UniProtKB P11586.
ProteinModelPortal	Q7ZXF4.
SMR	Q7ZXF4. Positions 2-294, 468-530.
ModBase	Search...
Proteomic databases
PRIDE	Q7ZXF4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	380266.
KEGG	xla:380266.
Organism-specific databases
CTD	4522.
Xenbase	XB-GENE-992138. mthfd1.
Phylogenomic databases
HOVERGEN	HBG004916.
KO	K00288.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
HAMAP	MF_01543. FTHFS. MF_01576. THF_DHG_CYH.
InterPro	IPR000559. Formate_THF_ligase. IPR020628. Formate_THF_ligase_CS. IPR016040. NAD(P)-bd_dom. IPR000672. THF_DH/CycHdrlase. IPR020630. THF_DH/CycHdrlase_cat_dom. IPR020867. THF_DH/CycHdrlase_CS. IPR020631. THF_DH/CycHdrlase_NAD-bd_dom. [Graphical view]
Pfam	PF01268. FTHFS. 1 hit. PF00763. THF_DHG_CYH. 1 hit. PF02882. THF_DHG_CYH_C. 1 hit. [Graphical view]
PRINTS	PR00085. THFDHDRGNASE.
PROSITE	PS00721. FTHFS_1. 1 hit. PS00722. FTHFS_2. 1 hit. PS00766. THF_DHG_CYH_1. 1 hit. PS00767. THF_DHG_CYH_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7ZXF4_XENLA

Accession

Primary (citable) accession number: Q7ZXF4

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	March 6, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)