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Protein

Lipase maturation factor 2

Gene

lmf2

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in the maturation of specific proteins in the endoplasmic reticulum.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Lipase maturation factor 2
Gene namesi
Name:lmf2
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-974445. lmf2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei10 – 30HelicalSequence analysisAdd BLAST21
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21
Transmembranei126 – 146HelicalSequence analysisAdd BLAST21
Transmembranei158 – 178HelicalSequence analysisAdd BLAST21
Transmembranei220 – 240HelicalSequence analysisAdd BLAST21
Transmembranei256 – 276HelicalSequence analysisAdd BLAST21
Transmembranei309 – 329HelicalSequence analysisAdd BLAST21
Transmembranei358 – 378HelicalSequence analysisAdd BLAST21
Transmembranei395 – 415HelicalSequence analysisAdd BLAST21
Transmembranei634 – 654HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003245141 – 707Lipase maturation factor 2Add BLAST707

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi483N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Family & Domainsi

Sequence similaritiesi

Belongs to the lipase maturation factor family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG108090.

Family and domain databases

InterProiView protein in InterPro
IPR009613. LMF.
PfamiView protein in Pfam
PF06762. LMF1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7ZWN0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEHRLARSA FLWGLSGIYL FAFVSLYVQI PGLYGREGIL PAWKMLRFTG
60 70 80 90 100
KGFWEQMKDS PSLLWFGPRL GLDTEMTMEL ICLLGALLSL GALLFSCLRD
110 120 130 140 150
SLVFLLLWVF YLSLYQVGQV FLYFQWDSLL LETGFLAILV APLHAMRWKT
160 170 180 190 200
SVWSAHDGVT FWLTRWLLFR LMFASGVVKL TSRCPTWWGL TALTYHYETQ
210 220 230 240 250
CIPNPAAWYA HQLPVWLQKF SVVATFFIEI GVPWLFFLPF RRLRLFSFYS
260 270 280 290 300
QVLLQILIII TGNYNFFNLL TIVLCCSMLD DQHIAFFQRH KKTQHKGGIA
310 320 330 340 350
TSAFSLRSLV SLLEIPIFGL LVFWTVKYFD LQINWDKHSL ESRTAFTYHD
360 370 380 390 400
FQQWLRTITF PSIWIAAASL GWEILKGMYR SASVRGFFWK LWSTLQWLMF
410 420 430 440 450
SCAAAAMFTI SLVPYTYMDF ESNGQLWPEV HQMFNTVDRY QLVNSYGLFR
460 470 480 490 500
RMTGVGGRPE VVVEGSFDRE TWTEIEFMYK PGNISTIPTV IVPHQPRLDW
510 520 530 540 550
QMWFAALSHH SHSPWFASFV YRLLQGNKDV IHLVQNDESL YPFHANPPTY
560 570 580 590 600
IRAQQYKYWF TEVDQSGHMP KSWWRRRHVE EFFPAVFLDD PFLDNLLSQH
610 620 630 640 650
GLKDKPPARR SLDAPIPFVL KLIRDFLHPL PAPLLLHSFI FGIFTIYFLQ
660 670 680 690 700
AMFGGVSRPS VAKQRHSMPP NEKKKQKPNS GQGESASSKS SGHGTDTVRR

NKKNEKS
Length:707
Mass (Da):82,267
Last modified:June 1, 2003 - v1
Checksum:iB37A31482CF5CB92
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC046869 mRNA. Translation: AAH46869.1.
RefSeqiNP_001079679.1. NM_001086210.1.
UniGeneiXl.19445.

Genome annotation databases

GeneIDi379366.
KEGGixla:379366.

Similar proteinsi

Entry informationi

Entry nameiLMF2_XENLA
AccessioniPrimary (citable) accession number: Q7ZWN0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: June 1, 2003
Last modified: May 10, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families