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Q7ZW24

- ALG11_DANRE

UniProt

Q7ZW24 - ALG11_DANRE

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Protein

GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

Gene

alg11

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

2 GDP-alpha-D-mannose + D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = 2 GDP + D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol.

GO - Molecular functioni

  1. GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Names & Taxonomyi

Protein namesi
Recommended name:
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC:2.4.1.131)
Alternative name(s):
Asparagine-linked glycosylation protein 11 homolog
Glycolipid 2-alpha-mannosyltransferase
Gene namesi
Name:alg11
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Unplaced

Organism-specific databases

ZFINiZDB-GENE-030131-7282. alg11.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 500500GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferasePRO_0000295619Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000049513.

Structurei

3D structure databases

ProteinModelPortaliQ7ZW24.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei21 – 4121HelicalSequence AnalysisAdd
BLAST
Transmembranei226 – 24621HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0438.
HOGENOMiHOG000209670.
HOVERGENiHBG057178.
InParanoidiQ7ZW24.
PhylomeDBiQ7ZW24.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
[Graphical view]
PfamiPF00534. Glycos_transf_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7ZW24-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSAHDHFSLC LCDLIRLLWS LMLPCFYLSF LLTTILFLFI MGVRSWLQMK
60 70 80 90 100
RKTRRVQDGR PAVAFFHPYC NAGGGGERVL WCALRALQNR YQDVSFVVYT
110 120 130 140 150
GDQGVTAEEI LDGARRRFNI RLPRPVKFVF LKHRLLVEAK LYPHFTLLGQ
160 170 180 190 200
SVGSIFLGWE ALTEFVPDLY IDSMGFAFTL PVFRYLGGCQ VGSYVHYPTI
210 220 230 240 250
STDMLSVVRE RNPRFNNADY ISSNPVLSAI KVIYYCVFAL LYGLAGSCSD
260 270 280 290 300
VIMVNSTWTL GHILALWRTP NRTSVVYPPC DVQAFLDVPI GEDNEEKEQK
310 320 330 340 350
KCHSLVSVGQ FRPEKDHQLQ IRAFKKLLDR KEAEPAGREA VKLVLIGGCR
360 370 380 390 400
NQEDEDRVLM LRGLCQELGI ADRVEFKLNI PFQELKKDLT DATIGLHTMW
410 420 430 440 450
NEHFGIGIVE CMAAGTIILA HKSGGPKLDI VVPYDGGPTG FLADDEDNYA
460 470 480 490 500
DAMERILSMS PATRLEMRRR ARLSVSRFSD QEFEGSFLSA MEPLMSTLRA
Length:500
Mass (Da):56,623
Last modified:July 24, 2007 - v2
Checksum:iCF3A77A19CE21836
GO

Sequence cautioni

The sequence AAH45321.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC045321 mRNA. Translation: AAH45321.1. Different initiation.
UniGeneiDr.78139.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC045321 mRNA. Translation: AAH45321.1 . Different initiation.
UniGenei Dr.78139.

3D structure databases

ProteinModelPortali Q7ZW24.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7955.ENSDARP00000049513.

Protein family/group databases

CAZyi GT4. Glycosyltransferase Family 4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

ZFINi ZDB-GENE-030131-7282. alg11.

Phylogenomic databases

eggNOGi COG0438.
HOGENOMi HOG000209670.
HOVERGENi HBG057178.
InParanoidi Q7ZW24.
PhylomeDBi Q7ZW24.

Miscellaneous databases

PROi Q7ZW24.

Family and domain databases

InterProi IPR001296. Glyco_trans_1.
[Graphical view ]
Pfami PF00534. Glycos_transf_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: AB.

Entry informationi

Entry nameiALG11_DANRE
AccessioniPrimary (citable) accession number: Q7ZW24
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 24, 2007
Last modified: October 1, 2014
This is version 61 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3