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Q7ZW24

- ALG11_DANRE

UniProt

Q7ZW24 - ALG11_DANRE

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Protein
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
Gene
alg11
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

2 GDP-alpha-D-mannose + D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = 2 GDP + D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol.

GO - Molecular functioni

  1. GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Names & Taxonomyi

Protein namesi
Recommended name:
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC:2.4.1.131)
Alternative name(s):
Asparagine-linked glycosylation protein 11 homolog
Glycolipid 2-alpha-mannosyltransferase
Gene namesi
Name:alg11
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Unplaced

Organism-specific databases

ZFINiZDB-GENE-030131-7282. alg11.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei21 – 4121Helical; Reviewed prediction
Add
BLAST
Transmembranei226 – 24621Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 500500GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
PRO_0000295619Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000049513.

Structurei

3D structure databases

ProteinModelPortaliQ7ZW24.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0438.
HOGENOMiHOG000209670.
HOVERGENiHBG057178.
InParanoidiQ7ZW24.
PhylomeDBiQ7ZW24.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
[Graphical view]
PfamiPF00534. Glycos_transf_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7ZW24-1 [UniParc]FASTAAdd to Basket

« Hide

MSAHDHFSLC LCDLIRLLWS LMLPCFYLSF LLTTILFLFI MGVRSWLQMK    50
RKTRRVQDGR PAVAFFHPYC NAGGGGERVL WCALRALQNR YQDVSFVVYT 100
GDQGVTAEEI LDGARRRFNI RLPRPVKFVF LKHRLLVEAK LYPHFTLLGQ 150
SVGSIFLGWE ALTEFVPDLY IDSMGFAFTL PVFRYLGGCQ VGSYVHYPTI 200
STDMLSVVRE RNPRFNNADY ISSNPVLSAI KVIYYCVFAL LYGLAGSCSD 250
VIMVNSTWTL GHILALWRTP NRTSVVYPPC DVQAFLDVPI GEDNEEKEQK 300
KCHSLVSVGQ FRPEKDHQLQ IRAFKKLLDR KEAEPAGREA VKLVLIGGCR 350
NQEDEDRVLM LRGLCQELGI ADRVEFKLNI PFQELKKDLT DATIGLHTMW 400
NEHFGIGIVE CMAAGTIILA HKSGGPKLDI VVPYDGGPTG FLADDEDNYA 450
DAMERILSMS PATRLEMRRR ARLSVSRFSD QEFEGSFLSA MEPLMSTLRA 500
Length:500
Mass (Da):56,623
Last modified:July 24, 2007 - v2
Checksum:iCF3A77A19CE21836
GO

Sequence cautioni

The sequence AAH45321.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC045321 mRNA. Translation: AAH45321.1. Different initiation.
UniGeneiDr.78139.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC045321 mRNA. Translation: AAH45321.1 . Different initiation.
UniGenei Dr.78139.

3D structure databases

ProteinModelPortali Q7ZW24.
ModBasei Search...

Protein-protein interaction databases

STRINGi 7955.ENSDARP00000049513.

Protein family/group databases

CAZyi GT4. Glycosyltransferase Family 4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

ZFINi ZDB-GENE-030131-7282. alg11.

Phylogenomic databases

eggNOGi COG0438.
HOGENOMi HOG000209670.
HOVERGENi HBG057178.
InParanoidi Q7ZW24.
PhylomeDBi Q7ZW24.

Miscellaneous databases

PROi Q7ZW24.

Family and domain databases

InterProi IPR001296. Glyco_trans_1.
[Graphical view ]
Pfami PF00534. Glycos_transf_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: AB.

Entry informationi

Entry nameiALG11_DANRE
AccessioniPrimary (citable) accession number: Q7ZW24
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 24, 2007
Last modified: April 16, 2014
This is version 60 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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