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Q7ZW24

- ALG11_DANRE

UniProt

Q7ZW24 - ALG11_DANRE

Protein

GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

Gene

alg11

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 2 (24 Jul 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    2 GDP-alpha-D-mannose + D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = 2 GDP + D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol.

    GO - Molecular functioni

    1. GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Protein family/group databases

    CAZyiGT4. Glycosyltransferase Family 4.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC:2.4.1.131)
    Alternative name(s):
    Asparagine-linked glycosylation protein 11 homolog
    Glycolipid 2-alpha-mannosyltransferase
    Gene namesi
    Name:alg11
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
    ProteomesiUP000000437: Unplaced

    Organism-specific databases

    ZFINiZDB-GENE-030131-7282. alg11.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 500500GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferasePRO_0000295619Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi7955.ENSDARP00000049513.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7ZW24.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei21 – 4121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei226 – 24621HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0438.
    HOGENOMiHOG000209670.
    HOVERGENiHBG057178.
    InParanoidiQ7ZW24.
    PhylomeDBiQ7ZW24.

    Family and domain databases

    InterProiIPR001296. Glyco_trans_1.
    [Graphical view]
    PfamiPF00534. Glycos_transf_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7ZW24-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAHDHFSLC LCDLIRLLWS LMLPCFYLSF LLTTILFLFI MGVRSWLQMK    50
    RKTRRVQDGR PAVAFFHPYC NAGGGGERVL WCALRALQNR YQDVSFVVYT 100
    GDQGVTAEEI LDGARRRFNI RLPRPVKFVF LKHRLLVEAK LYPHFTLLGQ 150
    SVGSIFLGWE ALTEFVPDLY IDSMGFAFTL PVFRYLGGCQ VGSYVHYPTI 200
    STDMLSVVRE RNPRFNNADY ISSNPVLSAI KVIYYCVFAL LYGLAGSCSD 250
    VIMVNSTWTL GHILALWRTP NRTSVVYPPC DVQAFLDVPI GEDNEEKEQK 300
    KCHSLVSVGQ FRPEKDHQLQ IRAFKKLLDR KEAEPAGREA VKLVLIGGCR 350
    NQEDEDRVLM LRGLCQELGI ADRVEFKLNI PFQELKKDLT DATIGLHTMW 400
    NEHFGIGIVE CMAAGTIILA HKSGGPKLDI VVPYDGGPTG FLADDEDNYA 450
    DAMERILSMS PATRLEMRRR ARLSVSRFSD QEFEGSFLSA MEPLMSTLRA 500
    Length:500
    Mass (Da):56,623
    Last modified:July 24, 2007 - v2
    Checksum:iCF3A77A19CE21836
    GO

    Sequence cautioni

    The sequence AAH45321.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC045321 mRNA. Translation: AAH45321.1. Different initiation.
    UniGeneiDr.78139.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC045321 mRNA. Translation: AAH45321.1 . Different initiation.
    UniGenei Dr.78139.

    3D structure databases

    ProteinModelPortali Q7ZW24.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7955.ENSDARP00000049513.

    Protein family/group databases

    CAZyi GT4. Glycosyltransferase Family 4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    ZFINi ZDB-GENE-030131-7282. alg11.

    Phylogenomic databases

    eggNOGi COG0438.
    HOGENOMi HOG000209670.
    HOVERGENi HBG057178.
    InParanoidi Q7ZW24.
    PhylomeDBi Q7ZW24.

    Miscellaneous databases

    PROi Q7ZW24.

    Family and domain databases

    InterProi IPR001296. Glyco_trans_1.
    [Graphical view ]
    Pfami PF00534. Glycos_transf_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Zebrafish Gene Collection (ZGC) project
      Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: AB.

    Entry informationi

    Entry nameiALG11_DANRE
    AccessioniPrimary (citable) accession number: Q7ZW24
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 24, 2007
    Last sequence update: July 24, 2007
    Last modified: October 1, 2014
    This is version 61 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3