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Protein
Submitted name:

Ucp4 protein

Gene

ucp1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • cellular response to estrogen stimulus Source: ZFIN
  • mitochondrial transport Source: InterPro
Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotation

Enzyme and pathway databases

ReactomeiR-DRE-167826. The fatty acid cycling model.
R-DRE-167827. The proton buffering model.

Names & Taxonomyi

Protein namesi
Submitted name:
Ucp4 proteinImported
Submitted name:
Uncharacterized proteinImported
Submitted name:
Uncoupling protein 4Imported
Gene namesi
Name:ucp1Imported
Synonyms:ucp4Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 1

Organism-specific databases

ZFINiZDB-GENE-010503-1. ucp1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000037614.

Family & Domainsi

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG0753. Eukaryota.
ENOG410XRV1. LUCA.
GeneTreeiENSGT00760000119170.
HOVERGENiHBG009528.
KOiK15103.
OrthoDBiEOG793B7Z.
TreeFamiTF323211.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002030. Mit_uncoupling.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00784. MTUNCOUPLING.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7ZVP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGLKPSDVP PPLTVKVLSA GTAACIADLV TFPLDTAKVR LQIQGEKAVT
60 70 80 90 100
GAAKGIRYKG VFGTISTMMR TEGPRSLYNG LVAGLQRQMA FASIRIGLYD
110 120 130 140 150
NVKSFYTRGK DNPNVAVRIL AGCTTGAMAV SMAQPTDVVK VRFQAQMNLQ
160 170 180 190 200
GVGRRYNGTM QAYRQIFQLE GLRGLWKGTL PNITRNALVN CTELVSYDLI
210 220 230 240 250
KEAILKHRLL SDNLPCHFVS AFGAGFITTV IASPVDVVKT RYMNSPPGQY
260 270 280 290 300
SSSTNCAWTM LTKEGPTAFY KGFVPSFLRL GSWNVVMFVS FEQLKRAMMV

SRNRIEAAA
Length:309
Mass (Da):33,766
Last modified:June 1, 2003 - v1
Checksum:iC10F7E4C1FECB829
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935166 Genomic DNA. No translation available.
BC045464 mRNA. Translation: AAH45464.1.
BC063945 mRNA. Translation: AAH63945.1.
BC075906 mRNA. Translation: AAH75906.1.
BC164087 mRNA. Translation: AAI64087.1.
RefSeqiNP_955817.1. NM_199523.2.
UniGeneiDr.77108.

Genome annotation databases

EnsembliENSDART00000038807; ENSDARP00000037614; ENSDARG00000023151.
GeneIDi83908.
KEGGidre:83908.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935166 Genomic DNA. No translation available.
BC045464 mRNA. Translation: AAH45464.1.
BC063945 mRNA. Translation: AAH63945.1.
BC075906 mRNA. Translation: AAH75906.1.
BC164087 mRNA. Translation: AAI64087.1.
RefSeqiNP_955817.1. NM_199523.2.
UniGeneiDr.77108.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000037614.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000038807; ENSDARP00000037614; ENSDARG00000023151.
GeneIDi83908.
KEGGidre:83908.

Organism-specific databases

CTDi7350.
ZFINiZDB-GENE-010503-1. ucp1.

Phylogenomic databases

eggNOGiKOG0753. Eukaryota.
ENOG410XRV1. LUCA.
GeneTreeiENSGT00760000119170.
HOVERGENiHBG009528.
KOiK15103.
OrthoDBiEOG793B7Z.
TreeFamiTF323211.

Enzyme and pathway databases

ReactomeiR-DRE-167826. The fatty acid cycling model.
R-DRE-167827. The proton buffering model.

Miscellaneous databases

NextBioi20934193.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002030. Mit_uncoupling.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00784. MTUNCOUPLING.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: ABImported.
    Tissue: Whole bodyImported.
  2. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: WholeImported.
  3. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: WholeImported.
  4. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescueImported.
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  6. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiQ7ZVP4_DANRE
AccessioniPrimary (citable) accession number: Q7ZVP4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: May 11, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.