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Q7ZV00 (OTU6B_DANRE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
OTU domain-containing protein 6B

EC=3.4.19.12
Gene names
Name:otud6b
ORF Names:zgc:56305
OrganismDanio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome]
Taxonomic identifier7955 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Protein attributes

Sequence length293 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Sequence similarities

Contains 1 OTU domain.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   Molecular functionHydrolase
Protease
Thiol protease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processproteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functioncysteine-type peptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 293293OTU domain-containing protein 6B
PRO_0000076282

Regions

Domain147 – 284138OTU
Region152 – 1587Cys-loop By similarity
Region219 – 22911Variable-loop By similarity
Region267 – 27711His-loop By similarity

Sites

Active site1551 By similarity
Active site1581Nucleophile By similarity
Active site2771 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7ZV00 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: D8BE7A4E2742F3AB

FASTA29333,507
        10         20         30         40         50         60 
MEEVETAEEQ LAKQHRKEKK DLQAKIQSMK NAVPKNDKKR RKQLTEDIAK LEAELSQKHE 

        70         80         90        100        110        120 
NELKLQNTSS VEEVSDALDS MSVANHEEQS DPSKQSRTSK AQKRRDKKAA LEKEREMRIA 

       130        140        150        160        170        180 
EAEVENLSGS RHQEGLKLRE KLVERHLQIK EISSDGHCMY RAVEHQLTER GLALGLKELR 

       190        200        210        220        230        240 
DQTAQYMRSH ADDFMPFLTN PNTGDMYTAE EFEKYCSDVA DTAAWGGQLE LKALSQVLQL 

       250        260        270        280        290 
PIEVIQADSP CITIGEEYDK PKITLIYMRH AYGLGEHYNS VEPLKDLANE EEG 

« Hide

References

[1]NIH - Zebrafish Gene Collection (ZGC) project
Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC046060 mRNA. Translation: AAH46060.1.
RefSeqNP_956519.1. NM_200225.1.
UniGeneDr.16650.

3D structure databases

ProteinModelPortalQ7ZV00.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7955.ENSDARP00000029725.

Proteomic databases

PRIDEQ7ZV00.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID393194.
KEGGdre:393194.

Organism-specific databases

CTD51633.
ZFINZDB-GENE-040426-974. otud6b.

Phylogenomic databases

eggNOGCOG5539.
HOGENOMHOG000192906.
HOVERGENHBG080227.
PhylomeDBQ7ZV00.

Family and domain databases

InterProIPR003323. OTU.
[Graphical view]
PfamPF02338. OTU. 1 hit.
[Graphical view]
PROSITEPS50802. OTU. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20814259.
PROQ7ZV00.

Entry information

Entry nameOTU6B_DANRE
AccessionPrimary (citable) accession number: Q7ZV00
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: June 1, 2003
Last modified: April 16, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families