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Protein

Aspartate aminotransferase

Gene

got1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.UniRule annotation

Catalytic activityi

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferaseUniRule annotation, Transferase

Enzyme and pathway databases

ReactomeiR-DRE-70263 Gluconeogenesis
R-DRE-70614 Amino acid synthesis and interconversion (transamination)

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate aminotransferaseUniRule annotation (EC:2.6.1.1UniRule annotation)
Gene namesi
Name:got1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 13

Organism-specific databases

ZFINiZDB-GENE-040426-2003 got1

Expressioni

Gene expression databases

BgeeiENSDARG00000039093

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi7955.ENSDARP00000057089

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 402Aminotran_1_2InterPro annotationAdd BLAST374

Phylogenomic databases

GeneTreeiENSGT00390000014081
HOGENOMiHOG000205084
HOVERGENiHBG000951
KOiK14454
OMAiIAEVMMR
OrthoDBiEOG091G06G3

Family and domain databases

Gene3Di3.40.640.101 hit
3.90.1150.102 hits
InterProiView protein in InterPro
IPR004839 Aminotransferase_I/II
IPR000796 Asp_trans
IPR004838 NHTrfase_class1_PyrdxlP-BS
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR11879 PTHR11879, 1 hit
PfamiView protein in Pfam
PF00155 Aminotran_1_2, 1 hit
PRINTSiPR00799 TRANSAMINASE
SUPFAMiSSF53383 SSF53383, 1 hit
PROSITEiView protein in PROSITE
PS00105 AA_TRANSFER_CLASS_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q7ZUW8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIFGEVPQA APVAVFKLTA DFREDQDQKK VNLGVGAYRT DECQPWVLPV
60 70 80 90 100
VRKVEKMIAD DHSLNHEYLP ILGLPEFRSS ASKIALGEDS PAIKENRVGA
110 120 130 140 150
VQCLGGTGAL KIGAEFLRRW YNGTDNTKTP VYVSAPTWEN HNAVFSNAGF
160 170 180 190 200
EDIRPYKYWD PVKRGLDLAG FLGDMESAPD HSIFVLHACA HNPTGTDPTQ
210 220 230 240 250
DQWKQIAEVM KRKNLFAFFD SAYQGFASGD LEKDAWAVRY FVSQGFELFC
260 270 280 290 300
AQSFSKNFGL YNERVGNLTV VAKDQDNVNR VLSQMEKIVR ITWSNPPSQG
310 320 330 340 350
ARLVAITLNT PELFAEWKAN VKTMADRVLL MRAQLKEKLK ALGTPGTWEH
360 370 380 390 400
ITEQIGMFSF TGLNPKQVEY MIKEKHIYLM ASGRINMCGL TSKNIDYVAE
410
SIHEAVTKVQ
Length:410
Mass (Da):45,982
Last modified:June 1, 2003 - v1
Checksum:i03949B6BF84D2383
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX005330 Genomic DNA No translation available.
CU929568 Genomic DNA No translation available.
BC047800 mRNA Translation: AAH47800.1
BC155112 mRNA Translation: AAI55113.1
BC164786 mRNA Translation: AAI64786.1
RefSeqiNP_998222.1, NM_213057.2
XP_017214217.1, XM_017358728.1
UniGeneiDr.75522

Genome annotation databases

EnsembliENSDART00000167859; ENSDARP00000129948; ENSDARG00000039093
GeneIDi406330
KEGGidre:406330

Similar proteinsi

Entry informationi

Entry nameiQ7ZUW8_DANRE
AccessioniPrimary (citable) accession number: Q7ZUW8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: April 25, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported