Q7ZUS3 (Q7ZUS3_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GAD67 EMBL BAD67441.1

Submitted name:
Glutamate decarboxylase 1 EMBL AAH47851.1
Submitted name:
Uncharacterized protein Ensembl ENSDARP00000024162

Gene names

Name:	gad1b Ensembl ENSDARP00000024162 ZFIN ZDB-GENE-030909-3
Synonyms:	gad1 ZFIN ZDB-GENE-030909-3 EMBL AAH47851.1, GAD67 EMBL BAD67441.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome]

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Otocephala › Ostariophysi › Otophysi › Cypriniphysi › Cypriniformes › Cyprinoidea › Cyprinidae › Danio

Protein attributes

Sequence length	587 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	carboxylic acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	carboxy-lyase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7ZUS3 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 1CF1FB099242491E	FASTA	587	66,156
	10 20 30 40 50 60 MASSAPSSSA GDMDPNTANL RQPATTSDAW YGVAHGCTRK LGMKICGFLQ KNNSLDEKSR 70 80 90 100 110 120 MVGSFKESAK NQMSCDNNER FTRDETDFSN LFARDLLPAK NGEEPTIQFL LEVVEILTNY 130 140 150 160 170 180 VRKTFDRSTK VLDFHHPHQL LEGMEGFNLE LSDQPESLEQ ILVDCRDTLK YGVRTGHPRF 190 200 210 220 230 240 FNQLSSGLDI IGLAGEWLTS TANTNMFTYE IAPVFVLMEQ LTLKKMREII GWPNGDGDAL 250 260 270 280 290 300 FSPGGAISNM YSVMVARYKY FPEVKTKGMS AAPRLVLFTS EHSHYSIKKA GAVLGFGKEN 310 320 330 340 350 360 VILLKTDERG RVIPADLEAK VIDAKQKGYV PLFVNATAGT TVYGAFDPIN DIADICEKYN 370 380 390 400 410 420 LWLHVDGAWG GGLLMSRKHR HKLSGIERAN SVTWNPHKMM GVPLQCSAIL VREKGILQGC 430 440 450 460 470 480 NSMCAGYLFQ PDKQYDVTYD TGDKAIQCGR HVDIFKFWLM WKAKGTIGFE QHIDRCLELS 490 500 510 520 530 540 EYLYNKIKNR EGYEMVFEGQ PQHTNVCFWY IPPSLRGMPN GDERREKLHR VAPKIKAMMM 550 560 570 580 ECGTTMVGYQ PQGDKVNFFR MVVSNHAVTK SDIDFLIDEI ERLGQDL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Whole body EMBL AAH47851.1.
[2]	"Distribution of prospective glutamatergic, glycinergic, and GABAergic neurons in embryonic and larval zebrafish." Higashijima S., Mandel G., Fetcho J.R. J. Comp. Neurol. 480:1-18(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000024162.
[4]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000024162.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR384078 Genomic DNA. No translation available. BC047851 mRNA. Translation: AAH47851.1. AB183390 mRNA. Translation: BAD67441.1.
IPI	IPI00481585.
RefSeq	NP_919400.1. NM_194419.1.
UniGene	Dr.81985.
3D structure databases
SMR	Q7ZUS3. Positions 86-586.
ModBase	Search...
Protein-protein interaction databases
STRING	7955.ENSDARP00000024162.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000003008; ENSDARP00000024162; ENSDARG00000027419.
GeneID	378441.
KEGG	dre:378441.
Organism-specific databases
CTD	378441.
ZFIN	ZDB-GENE-030909-3. gad1b.
Phylogenomic databases
eggNOG	COG0076.
GeneTree	ENSGT00550000074275.
HOGENOM	HOG000005382.
HOVERGEN	HBG004980.
KO	K01580.
OMA	ISMAGEW.
Family and domain databases
Gene3D	3.40.640.10. 1 hit. 3.90.1150.10. 1 hit.
InterPro	IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. IPR021115. Pyridoxal-P_BS. [Graphical view]
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITE	PS00392. DDC_GAD_HDC_YDC. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20813769.

Entry information

Entry name

Q7ZUS3_DANRE

Accession

Primary (citable) accession number: Q7ZUS3

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	April 3, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)