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Protein
Submitted name:

GAD67

Gene

gad1b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

  • gamma-aminobutyric acid biosynthetic process Source: ZFIN
  • neurotransmitter biosynthetic process Source: ZFIN

Keywordsi

Molecular functionLyaseUniRule annotation
LigandPyridoxal phosphateUniRule annotation

Enzyme and pathway databases

ReactomeiR-DRE-888568. GABA synthesis.
R-DRE-888590. GABA synthesis, release, reuptake and degradation.

Names & Taxonomyi

Protein namesi
Submitted name:
GAD67Imported
Submitted name:
Glutamate decarboxylase 1Imported
Submitted name:
Glutamate decarboxylase 1bImported
Gene namesi
Name:gad1bImported
Synonyms:gad1Imported, GAD67Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 6

Organism-specific databases

ZFINiZDB-GENE-030909-3. gad1b.

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei398N6-(pyridoxal phosphate)lysineUniRule annotation1

Expressioni

Gene expression databases

BgeeiENSDARG00000027419.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0629. Eukaryota.
COG0076. LUCA.
GeneTreeiENSGT00760000119205.
HOGENOMiHOG000005382.
HOVERGENiHBG004980.
KOiK01580.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiView protein in InterPro
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_sub2.
IPR021115. Pyridoxal-P_BS.
PfamiView protein in Pfam
PF00282. Pyridoxal_deC. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiView protein in PROSITE
PS00392. DDC_GAD_HDC_YDC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7ZUS3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSAPSSSA GDMDPNTANL RQPATTSDAW YGVAHGCTRK LGMKICGFLQ
60 70 80 90 100
KNNSLDEKSR MVGSFKESAK NQMSCDNNER FTRDETDFSN LFARDLLPAK
110 120 130 140 150
NGEEPTIQFL LEVVEILTNY VRKTFDRSTK VLDFHHPHQL LEGMEGFNLE
160 170 180 190 200
LSDQPESLEQ ILVDCRDTLK YGVRTGHPRF FNQLSSGLDI IGLAGEWLTS
210 220 230 240 250
TANTNMFTYE IAPVFVLMEQ LTLKKMREII GWPNGDGDAL FSPGGAISNM
260 270 280 290 300
YSVMVARYKY FPEVKTKGMS AAPRLVLFTS EHSHYSIKKA GAVLGFGKEN
310 320 330 340 350
VILLKTDERG RVIPADLEAK VIDAKQKGYV PLFVNATAGT TVYGAFDPIN
360 370 380 390 400
DIADICEKYN LWLHVDGAWG GGLLMSRKHR HKLSGIERAN SVTWNPHKMM
410 420 430 440 450
GVPLQCSAIL VREKGILQGC NSMCAGYLFQ PDKQYDVTYD TGDKAIQCGR
460 470 480 490 500
HVDIFKFWLM WKAKGTIGFE QHIDRCLELS EYLYNKIKNR EGYEMVFEGQ
510 520 530 540 550
PQHTNVCFWY IPPSLRGMPN GDERREKLHR VAPKIKAMMM ECGTTMVGYQ
560 570 580
PQGDKVNFFR MVVSNHAVTK SDIDFLIDEI ERLGQDL
Length:587
Mass (Da):66,156
Last modified:June 1, 2003 - v1
Checksum:i1CF1FB099242491E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR384078 Genomic DNA. No translation available.
BC047851 mRNA. Translation: AAH47851.1.
AB183390 mRNA. Translation: BAD67441.1.
RefSeqiNP_919400.1. NM_194419.1.
XP_009300378.1. XM_009302103.2.
UniGeneiDr.81985.

Genome annotation databases

EnsembliENSDART00000003008; ENSDARP00000024162; ENSDARG00000027419.
GeneIDi378441.
KEGGidre:378441.

Similar proteinsi

Entry informationi

Entry nameiQ7ZUS3_DANRE
AccessioniPrimary (citable) accession number: Q7ZUS3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: August 30, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported