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Q7ZUM3

- Q7ZUM3_DANRE

UniProt

Q7ZUM3 - Q7ZUM3_DANRE

Protein
Submitted name:

Hexokinase 1

Gene

hk1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. fructokinase activity Source: RefGenome
    3. glucokinase activity Source: RefGenome
    4. mannokinase activity Source: RefGenome

    GO - Biological processi

    1. carbohydrate phosphorylation Source: GOC
    2. cellular glucose homeostasis Source: RefGenome
    3. glucose 6-phosphate metabolic process Source: GOC
    4. glycolytic process Source: RefGenome

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    GlycolysisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Hexokinase 1Imported
    Gene namesi
    Name:hk1Imported
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

    Organism-specific databases

    ZFINiZDB-GENE-040426-2848. hk1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: RefGenome

    PTM / Processingi

    Proteomic databases

    PRIDEiQ7ZUM3.

    Expressioni

    Gene expression databases

    BgeeiQ7ZUM3.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7ZUM3.
    SMRiQ7ZUM3. Positions 16-914.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the hexokinase family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG005020.
    InParanoidiQ7ZUM3.
    KOiK00844.
    PhylomeDBiQ7ZUM3.

    Family and domain databases

    InterProiIPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view]
    PANTHERiPTHR19443. PTHR19443. 1 hit.
    PfamiPF00349. Hexokinase_1. 2 hits.
    PF03727. Hexokinase_2. 2 hits.
    [Graphical view]
    PRINTSiPR00475. HEXOKINASE.
    PROSITEiPS00378. HEXOKINASES. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7ZUM3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIAAQLLAYY FTELKDDQVK KIDKYLYAMR FSDETLRDIM ARFRREMENG    50
    LARDTNPTAT AKMLPTFVRS IPDGSEKGDF IALDLGGSNF RILRVKVSHE 100
    KKQTVQMESQ IYETPEDIIH GSRSRLFDHV AECLGDFMEK QKIKDKKLPV 150
    GFTFSFPCSQ SKLDEAVLLT WTKRFKVNGV EGMDVVKLLN KAIKKRGDYE 200
    ADIMAVVNDT VGTMMTCGFD DQRCEVGIII GTGTNACYME ELRHMDMVEG 250
    DEGRMCINTE WGAFGDDGTL EDIRTEFDRE IDRGSLNPGK QLFEKMVSGM 300
    YMGELVRLIL VKMAKEGLLF EGRITPELLT KGKIETKHVS AIEKSKEGLT 350
    KAKEILTRLG VEPSEDDCIA VQHVCAIVSF RSANLIAATL GAILTRLKDN 400
    KNTPRLRTTV GIDGSLYKMH PQYARRLHKT VRRLVPESDV RFLLSESGSG 450
    KGAALVTAWA YRLADQERQI AETLEEFRLT KDQLLEVKKR MRTEIQNGLS 500
    KSTQNTATVK MLPTYVRSTP DGSENGDFLA LDLGGTNFRV LLVKIRSGKR 550
    RTVEMHNKIY AIPIEVMQGT GEELFDHIVY CISDFLDYMG MKNARLPLGF 600
    TFSFPCRQTS LDAGLLVNWT KGFKATDCEG EDVVGLLREG IKRREEFDLD 650
    VVAIVNDTVG TMMTCAYEEP TCEVGLIAGT GSNACYMEEM RNIETVSGEE 700
    GRMCVNMEWG AFGDNGCLDD IRTKYDDAVD DLSLNAGKQK YEKMCSGMYL 750
    GEIVRNILID LTKRGFLFRG QISETLKTRG IFETKFLSQI ESDRLALLQV 800
    RSILQHLGLD STCDDSIIVK EVCGAVSRRA AQLCGAGMAA VVDKIRENRG 850
    LDHLDITVGV DGTLYKLHPH FSRIMHQTVK ELAPKCNVTF LLSEDGSGKG 900
    AALITAVGCR LRQQEQKS 918
    Length:918
    Mass (Da):102,828
    Last modified:June 1, 2003 - v1
    Checksum:i09E759B881F5DFAA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC048065 mRNA. Translation: AAH48065.1.
    RefSeqiNP_998417.1. NM_213252.1.
    UniGeneiDr.9278.

    Genome annotation databases

    GeneIDi406791.
    KEGGidre:406791.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC048065 mRNA. Translation: AAH48065.1 .
    RefSeqi NP_998417.1. NM_213252.1.
    UniGenei Dr.9278.

    3D structure databases

    ProteinModelPortali Q7ZUM3.
    SMRi Q7ZUM3. Positions 16-914.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q7ZUM3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 406791.
    KEGGi dre:406791.

    Organism-specific databases

    CTDi 3098.
    ZFINi ZDB-GENE-040426-2848. hk1.

    Phylogenomic databases

    HOVERGENi HBG005020.
    InParanoidi Q7ZUM3.
    KOi K00844.
    PhylomeDBi Q7ZUM3.

    Miscellaneous databases

    NextBioi 20818302.

    Gene expression databases

    Bgeei Q7ZUM3.

    Family and domain databases

    InterProi IPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view ]
    PANTHERi PTHR19443. PTHR19443. 1 hit.
    Pfami PF00349. Hexokinase_1. 2 hits.
    PF03727. Hexokinase_2. 2 hits.
    [Graphical view ]
    PRINTSi PR00475. HEXOKINASE.
    PROSITEi PS00378. HEXOKINASES. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Zebrafish Gene Collection (ZGC) project
      Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: ABImported.
      Tissue: Whole bodyImported.

    Entry informationi

    Entry nameiQ7ZUM3_DANRE
    AccessioniPrimary (citable) accession number: Q7ZUM3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)