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Q7ZUM3

- Q7ZUM3_DANRE

UniProt

Q7ZUM3 - Q7ZUM3_DANRE

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Protein
Submitted name: Hexokinase 1
Gene
hk1
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. fructokinase activity Source: RefGenome
  3. glucokinase activity Source: RefGenome
  4. mannokinase activity Source: RefGenome

GO - Biological processi

  1. carbohydrate phosphorylation Source: GOC
  2. cellular glucose homeostasis Source: RefGenome
  3. glucose 6-phosphate metabolic process Source: GOC
  4. glycolytic process Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase 1Imported
Gene namesi
Name:hk1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-040426-2848. hk1.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: RefGenome
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ7ZUM3.

Expressioni

Gene expression databases

BgeeiQ7ZUM3.

Structurei

3D structure databases

ProteinModelPortaliQ7ZUM3.
SMRiQ7ZUM3. Positions 16-914.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG005020.
InParanoidiQ7ZUM3.
KOiK00844.
PhylomeDBiQ7ZUM3.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7ZUM3-1 [UniParc]FASTAAdd to Basket

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MIAAQLLAYY FTELKDDQVK KIDKYLYAMR FSDETLRDIM ARFRREMENG    50
LARDTNPTAT AKMLPTFVRS IPDGSEKGDF IALDLGGSNF RILRVKVSHE 100
KKQTVQMESQ IYETPEDIIH GSRSRLFDHV AECLGDFMEK QKIKDKKLPV 150
GFTFSFPCSQ SKLDEAVLLT WTKRFKVNGV EGMDVVKLLN KAIKKRGDYE 200
ADIMAVVNDT VGTMMTCGFD DQRCEVGIII GTGTNACYME ELRHMDMVEG 250
DEGRMCINTE WGAFGDDGTL EDIRTEFDRE IDRGSLNPGK QLFEKMVSGM 300
YMGELVRLIL VKMAKEGLLF EGRITPELLT KGKIETKHVS AIEKSKEGLT 350
KAKEILTRLG VEPSEDDCIA VQHVCAIVSF RSANLIAATL GAILTRLKDN 400
KNTPRLRTTV GIDGSLYKMH PQYARRLHKT VRRLVPESDV RFLLSESGSG 450
KGAALVTAWA YRLADQERQI AETLEEFRLT KDQLLEVKKR MRTEIQNGLS 500
KSTQNTATVK MLPTYVRSTP DGSENGDFLA LDLGGTNFRV LLVKIRSGKR 550
RTVEMHNKIY AIPIEVMQGT GEELFDHIVY CISDFLDYMG MKNARLPLGF 600
TFSFPCRQTS LDAGLLVNWT KGFKATDCEG EDVVGLLREG IKRREEFDLD 650
VVAIVNDTVG TMMTCAYEEP TCEVGLIAGT GSNACYMEEM RNIETVSGEE 700
GRMCVNMEWG AFGDNGCLDD IRTKYDDAVD DLSLNAGKQK YEKMCSGMYL 750
GEIVRNILID LTKRGFLFRG QISETLKTRG IFETKFLSQI ESDRLALLQV 800
RSILQHLGLD STCDDSIIVK EVCGAVSRRA AQLCGAGMAA VVDKIRENRG 850
LDHLDITVGV DGTLYKLHPH FSRIMHQTVK ELAPKCNVTF LLSEDGSGKG 900
AALITAVGCR LRQQEQKS 918
Length:918
Mass (Da):102,828
Last modified:June 1, 2003 - v1
Checksum:i09E759B881F5DFAA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC048065 mRNA. Translation: AAH48065.1.
RefSeqiNP_998417.1. NM_213252.1.
UniGeneiDr.9278.

Genome annotation databases

GeneIDi406791.
KEGGidre:406791.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC048065 mRNA. Translation: AAH48065.1 .
RefSeqi NP_998417.1. NM_213252.1.
UniGenei Dr.9278.

3D structure databases

ProteinModelPortali Q7ZUM3.
SMRi Q7ZUM3. Positions 16-914.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q7ZUM3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 406791.
KEGGi dre:406791.

Organism-specific databases

CTDi 3098.
ZFINi ZDB-GENE-040426-2848. hk1.

Phylogenomic databases

HOVERGENi HBG005020.
InParanoidi Q7ZUM3.
KOi K00844.
PhylomeDBi Q7ZUM3.

Miscellaneous databases

NextBioi 20818302.

Gene expression databases

Bgeei Q7ZUM3.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: ABImported.
    Tissue: Whole bodyImported.

Entry informationi

Entry nameiQ7ZUM3_DANRE
AccessioniPrimary (citable) accession number: Q7ZUM3
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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