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Protein

Alkaline phosphatase

Gene

alpl

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Alkaline phosphataseUniRule annotation (EC:3.1.3.1UniRule annotation)
Gene namesi
Name:alplImported
Synonyms:alpImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-040420-1. alpl.

PTM / Processingi

Keywords - PTMi

PhosphoproteinUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ7ZTV9.
SMRiQ7ZTV9. Positions 56-386.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alkaline phosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1785.
HOGENOMiHOG000169979.
KOiK01077.
PhylomeDBiQ7ZTV9.

Family and domain databases

Gene3Di3.40.720.10. 1 hit.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR001952. Alkaline_phosphatase.
IPR018299. Alkaline_phosphatase_AS.
IPR017850. Alkaline_phosphatase_core.
[Graphical view]
PfamiPF00245. Alk_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00113. ALKPHPHTASE.
SMARTiSM00098. alkPPc. 1 hit.
[Graphical view]
SUPFAMiSSF53649. SSF53649. 1 hit.
PROSITEiPS00123. ALKALINE_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7ZTV9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWECGCFLVL WSELSVVWHP WNVKIRKRRL IDNKMKVAQL LILSCLVWEG
60 70 80 90 100
KTKVQFPEQE KRPDYWRDFA QRSLKDALKL QELNKNIAKN IILFLGDGMG
110 120 130 140 150
VPTVTAARIL KGQLSGQNGE ETQLEMDKFP HVALSKTYNT NAQVPDSAGT
160 170 180 190 200
ATAFLCGVKA NEGTVGVSAA AVRSQCNTTQ GNEVTSILKW AKDAGKSVGI
210 220 230 240 250
VTTTRVNHAT PSAAYAHCVD RDWYSDADMP NEALQSGCKD IARQLFENIP
260 270 280 290 300
DINVIMGGGR RSMYPKNTPD VEYPGDKKQN GTRKDGRNLV GEWIDRVKEK
310 320 330 340 350
RGYYVWNKKD LLSLNPNNVD YLLGLFEPAD LNYELERNTE NDPSLTEMVD
360 370 380 390 400
VAIKILKKNE RGFFLLVEGG RIDHGHHGSS SSRRPGAALH PSRHGLRRLH
410 420 430 440 450
RPEQRPLPDK LGLFFILQSH FSSTALSSLG QMAALLTLLL LLRCLQIKNF

P
Length:451
Mass (Da):50,592
Last modified:June 1, 2003 - v1
Checksum:i71CFFFD49C16EC17
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC052139 mRNA. Translation: AAH52139.1.
RefSeqiNP_957301.1. NM_201007.1.
UniGeneiDr.116988.

Genome annotation databases

GeneIDi393982.
KEGGidre:393982.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC052139 mRNA. Translation: AAH52139.1.
RefSeqiNP_957301.1. NM_201007.1.
UniGeneiDr.116988.

3D structure databases

ProteinModelPortaliQ7ZTV9.
SMRiQ7ZTV9. Positions 56-386.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi393982.
KEGGidre:393982.

Organism-specific databases

CTDi249.
ZFINiZDB-GENE-040420-1. alpl.

Phylogenomic databases

eggNOGiCOG1785.
HOGENOMiHOG000169979.
KOiK01077.
PhylomeDBiQ7ZTV9.

Miscellaneous databases

NextBioi20814952.

Family and domain databases

Gene3Di3.40.720.10. 1 hit.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR001952. Alkaline_phosphatase.
IPR018299. Alkaline_phosphatase_AS.
IPR017850. Alkaline_phosphatase_core.
[Graphical view]
PfamiPF00245. Alk_phosphatase. 1 hit.
[Graphical view]
PRINTSiPR00113. ALKPHPHTASE.
SMARTiSM00098. alkPPc. 1 hit.
[Graphical view]
SUPFAMiSSF53649. SSF53649. 1 hit.
PROSITEiPS00123. ALKALINE_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Whole bodyImported.

Entry informationi

Entry nameiQ7ZTV9_DANRE
AccessioniPrimary (citable) accession number: Q7ZTV9
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: July 22, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.