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Protein

Catalase

Gene

cat

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.UniRule annotation

Catalytic activityi

2 H2O2 = O2 + 2 H2O.UniRule annotation

Cofactori

hemeUniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei75 – 751UniRule annotation
Active sitei148 – 1481UniRule annotation
Metal bindingi358 – 3581Iron (heme axial ligand)UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxideUniRule annotation

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Protein family/group databases

PeroxiBasei8420. DrKat01.

Names & Taxonomyi

Protein namesi
Recommended name:
CatalaseUniRule annotation (EC:1.11.1.6UniRule annotation)
Gene namesi
Name:catImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-000210-20. cat.

PTM / Processingi

Proteomic databases

PaxDbiQ7ZTT1.
PRIDEiQ7ZTT1.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000013402.

Structurei

3D structure databases

ProteinModelPortaliQ7ZTT1.
SMRiQ7ZTT1. Positions 25-503.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini28 – 413386CatalaseInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the catalase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0047. Eukaryota.
COG0753. LUCA.
HOVERGENiHBG003986.

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7ZTT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADDREKSTD QMKLWKEGRG SQRPDVLTTG AGVPIGDKLN AMTAGPRGPL
60 70 80 90 100
LVQDVVFTDE MAHFDRERIP ERVVHAKGAG AFGYFEVTHD ITRYSKAKVF
110 120 130 140 150
EHVGKTTPIA VRFSTVAGEA GSSDTVRDPR GFAVKFYTDE GNWDLTGNNT
160 170 180 190 200
PIFFIRDTLL FPSFIHSQKR NPQTHLKDPD MVWDFWSLRP ESLHQVSFLF
210 220 230 240 250
SDRGIPDGYR HMNGYGSHTF KLVNAQGQPV YCKFHYKTNQ GIKNIPVEEA
260 270 280 290 300
DRLAATDPDY SIRDLYNAIA NGNFPSWTFY IQVMTFEQAE NWKWNPFDLT
310 320 330 340 350
KVWSHKEFPL IPVGRFVLNR NPVNYFAEVE QLAFDPSNMP PGIEPSPDKM
360 370 380 390 400
LQGRLFSYPD THRHRLGANY LQLPVNCPYR TRVANYQRDG PMCMHDNQGG
410 420 430 440 450
APNYYPNSFS APDVQPRFLE SKCKVSPDVA RYNSADDDNV TQVRTFFTQV
460 470 480 490 500
LNEAERERLC QNMAGHLKGA QLFIQKRMVQ NLMAVHSDYG NRVQALLDKH
510 520
NAEGKKNTVH VYSRGGASAV AAASKM
Length:526
Mass (Da):59,688
Last modified:June 1, 2003 - v1
Checksum:iFCA479E1DF97A43A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC051626 mRNA. Translation: AAH51626.1.
UniGeneiDr.1079.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC051626 mRNA. Translation: AAH51626.1.
UniGeneiDr.1079.

3D structure databases

ProteinModelPortaliQ7ZTT1.
SMRiQ7ZTT1. Positions 25-503.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000013402.

Protein family/group databases

PeroxiBasei8420. DrKat01.

Proteomic databases

PaxDbiQ7ZTT1.
PRIDEiQ7ZTT1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ZFINiZDB-GENE-000210-20. cat.

Phylogenomic databases

eggNOGiKOG0047. Eukaryota.
COG0753. LUCA.
HOVERGENiHBG003986.

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Whole bodyImported.

Entry informationi

Entry nameiQ7ZTT1_DANRE
AccessioniPrimary (citable) accession number: Q7ZTT1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: June 8, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.