Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ankyrin repeat domain-containing protein 1

Gene

ANKRD1

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes.By similarity

GO - Molecular functioni

GO - Biological processi

  • cellular response to growth factor stimulus Source: AgBase
  • myoblast differentiation Source: AgBase
  • negative regulation of apoptotic process Source: AgBase
  • negative regulation of gene expression Source: AgBase
  • positive regulation of gene expression Source: AgBase
  • positive regulation of myoblast proliferation Source: AgBase
  • post-embryonic development Source: AgBase
  • regulation of cell cycle Source: AgBase
  • skeletal muscle tissue development Source: AgBase
  • skeletal myofibril assembly Source: AgBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ankyrin repeat domain-containing protein 1
Alternative name(s):
Cardiac ankyrin repeat protein
Gene namesi
Name:ANKRD1
Synonyms:CARP
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

  • cell Source: AgBase
  • cytoplasm Source: AgBase
  • nucleus Source: AgBase
  • sarcomere Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 319319Ankyrin repeat domain-containing protein 1PRO_0000240484Add
BLAST

Proteomic databases

PaxDbiQ7ZT11.
PRIDEiQ7ZT11.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000010477.

Structurei

3D structure databases

ProteinModelPortaliQ7ZT11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati152 – 18130ANK 1Add
BLAST
Repeati185 – 21430ANK 2Add
BLAST
Repeati218 – 24730ANK 3Add
BLAST
Repeati251 – 28030ANK 4Add
BLAST
Repeati284 – 31532ANK 5Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi62 – 10847Lys-richAdd
BLAST

Sequence similaritiesi

Contains 5 ANK repeats.PROSITE-ProRule annotation

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
HOGENOMiHOG000236321.
HOVERGENiHBG071561.
InParanoidiQ7ZT11.
PhylomeDBiQ7ZT11.

Family and domain databases

Gene3Di1.25.40.20. 2 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 2 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 4 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7ZT11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMTMKVEELV TGKKTDDKES GSFLPEDFKT GEYEAAVKLE KQDDLRTASD
60 70 80 90 100
HLSTQVDMAH GKEKKREAEL KKKKLQERSK LESLEDLEKI IQLKKKKKCR
110 120 130 140 150
KVKAPLLKEP EPEVITGPVD IAMFFRAALE NKLPVIEKYL SDKGDPNVCN
160 170 180 190 200
EYKRTALHRA CSEGHLEVVK KLVEAGALLE LKDMLESTAL HWACRGGNLE
210 220 230 240 250
IVKFLLDKGI NRNARDKLRS TPLHVAVRTG QHDCAEHLIA CEADLNAKDR
260 270 280 290 300
EGDTPMHDAV RLNRYKMVRL LILYGADLTI KNVDGKTPMD LVLQWQNGTK
310
ELFNNLKNNS YKSAHLNKF
Length:319
Mass (Da):36,273
Last modified:June 1, 2003 - v1
Checksum:i7DE4B6B2AF6BB696
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB082934 mRNA. Translation: BAC66488.1.
AB082935 mRNA. Translation: BAC66489.1.
RefSeqiNP_989736.1. NM_204405.1.
UniGeneiGga.5751.

Genome annotation databases

GeneIDi378926.
KEGGigga:378926.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB082934 mRNA. Translation: BAC66488.1.
AB082935 mRNA. Translation: BAC66489.1.
RefSeqiNP_989736.1. NM_204405.1.
UniGeneiGga.5751.

3D structure databases

ProteinModelPortaliQ7ZT11.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000010477.

Proteomic databases

PaxDbiQ7ZT11.
PRIDEiQ7ZT11.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi378926.
KEGGigga:378926.

Organism-specific databases

CTDi27063.

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
HOGENOMiHOG000236321.
HOVERGENiHBG071561.
InParanoidiQ7ZT11.
PhylomeDBiQ7ZT11.

Miscellaneous databases

PROiQ7ZT11.

Family and domain databases

Gene3Di1.25.40.20. 2 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 2 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 4 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Chicken cardiac ankyrin repeat protein mRNA."
    Oda A., Uyeda A., Fujimori K., Kawasaki T., Taguchi T.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Skeletal muscle.

Entry informationi

Entry nameiANKR1_CHICK
AccessioniPrimary (citable) accession number: Q7ZT11
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 1, 2003
Last modified: June 8, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.