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Q7ZA46 (PGK_PICPA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:PGK1
OrganismKomagataella pastoris (Yeast) (Pichia pastoris)
Taxonomic identifier4922 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKomagataella

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 416416Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145886

Regions

Nucleotide binding371 – 3744ATP By similarity
Region24 – 263Substrate binding By similarity
Region63 – 664Substrate binding By similarity

Sites

Binding site391Substrate By similarity
Binding site1221Substrate By similarity
Binding site1691Substrate By similarity
Binding site2181ATP By similarity
Binding site3111ATP; via carbonyl oxygen By similarity
Binding site3421ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7ZA46 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: 9D01D41335F6DE07

FASTA41644,117
        10         20         30         40         50         60 
MSLSNKLSVK DLDVAGKRVF IRVDFNVPLD GDKITNNQRI VAALPTIQYV LDHKPKVVVL 

        70         80         90        100        110        120 
ASHLGRPNGE VNPKFSLKPV AAELSSLLGK KVTFLNDSVG PEVEKAVNSA SNGEVILLEN 

       130        140        150        160        170        180 
LRFHIEEEGS QKKDGQKIKA DKEAVARFRK QLTALADVYV NDAFGTAHRA HSSMVGFELE 

       190        200        210        220        230        240 
QRAAGFLMAK ELTYFAKALE NPVRPFLAIL GGAKVSDKIQ LIDNLLDKVD SIIIGGGMAF 

       250        260        270        280        290        300 
TFIKVLDNVA IGNSLFDEAG AKLVPGLVEK AKKNNVKLVL PVDFVTADAF SKDAKVGEAT 

       310        320        330        340        350        360 
VESGIPDGLQ GLDAGPKSRE LFAATIAEAK TIVWNGPPGV FEFDKFAEGT KSMLAAAIKN 

       370        380        390        400        410 
AQNGGTVIVG GGDTATVAKK FGGADKLSHV STGGGASLEL LEGKELPGVV YLSKKA 

« Hide

References

[1]Almeida J.R.M., Torres F.A.G.
Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY288296 Genomic DNA. Translation: AAP37611.1.

3D structure databases

ProteinModelPortalQ7ZA46.
SMRQ7ZA46. Positions 2-415.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ7ZA46.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_PICPA
AccessionPrimary (citable) accession number: Q7ZA46
Entry history
Integrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: October 1, 2003
Last modified: June 11, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families