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Q7ZA43 (GPD_PICAN) Reviewed, UniProtKB/Swiss-Prot

Last modified March 6, 2013. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]
EC=1.1.1.8
Gene names
Name:GPD
OrganismPichia angusta (Yeast) (Hansenula polymorpha)
Taxonomic identifier870730 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetales incertae sedis › Ogataea

Protein attributes

Sequence length381 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

Sequence similarities

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 381381Glycerol-3-phosphate dehydrogenase [NAD(+)]
PRO_0000138092

Regions

Nucleotide binding34 – 396NAD By similarity
Region303 – 3042Substrate binding By similarity

Sites

Active site2381Proton acceptor By similarity
Binding site1221NAD By similarity
Binding site1451NAD; via amide nitrogen By similarity
Binding site1451Substrate By similarity
Binding site1781NAD; via amide nitrogen By similarity
Binding site3031NAD By similarity
Binding site3321NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7ZA43 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: D1470A0A7B12D7C6

FASTA38142,205
        10         20         30         40         50         60 
MTAMDRLDHV SNQLAAKRQK KNPEGKPFRI TVVGSGNWGS TIAKVVAENA KELPEEFHQI 

        70         80         90        100        110        120 
VKMWVFEEEV DGRKLTEIIN TDHENVKYLP DVKLPDNIVA IPDIVDACAD ADIIIFNIPH 

       130        140        150        160        170        180 
QFLPKILAQL KGKVNPKARA ISCLKGLEVT KDGCKLLSNY ITEELGIYCG ALSGANLAPE 

       190        200        210        220        230        240 
VARQKWSETT VAYRIPQDFR GEGKDVDQSV IRNLFHRPYF HVRVIDDVAG VSLSGALKNV 

       250        260        270        280        290        300 
IAMAAGFVEG LGWGDNAKSA VMRIGLVEMI KFAHMFFEDC QSTTFTHESA GVADIITTCA 

       310        320        330        340        350        360 
GGRNVRVGRY MAEHKVSGFE AEKVLLNGQS CQGLHTTREV YELLAAKNVI DEFPLFKATY 

       370        380 
QIIYEGLPME KLPELLEASE D

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References

[1]"Yeast orthologues associated with glycerol transport and metabolism."
Neves L., Oliveira R., Lucas C.
FEMS Yeast Res. 5:51-62(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: IGc4129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AY289714 Genomic DNA. Translation: AAP44106.1.

3D structure databases

ProteinModelPortalQ7ZA43.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11728. PTHR11728. 1 hit.
PfamPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSPR00077. GPDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMsTIGR03376. glycerol3P_DH. 1 hit.
PROSITEPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGPD_PICAN
AccessionPrimary (citable) accession number: Q7ZA43
Entry history
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: October 1, 2003
Last modified: March 6, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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