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Q7Z7Q0

- Q7Z7Q0_HUMAN

UniProt

Q7Z7Q0 - Q7Z7Q0_HUMAN

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Protein
Submitted name: APOB protein
Gene
APOB
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. lipid transporter activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    APOB proteinImported
    Gene namesi
    Name:APOBImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA50.

    PTM / Processingi

    Proteomic databases

    PRIDEiQ7Z7Q0.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7Z7Q0.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG066906.
    KOiK14462.

    Family and domain databases

    Gene3Di1.25.10.20. 1 hit.
    2.20.50.20. 2 hits.
    2.30.230.10. 1 hit.
    InterProiIPR015819. Lipid_transp_b-sht_shell.
    IPR001747. Lipid_transpt_N.
    IPR015816. Vitellinogen_b-sht_N.
    IPR015255. Vitellinogen_open_b-sht.
    IPR015817. Vitellinogen_open_b-sht_sub1.
    IPR011030. Vitellinogen_superhlx.
    [Graphical view]
    PfamiPF09172. DUF1943. 1 hit.
    PF01347. Vitellogenin_N. 1 hit.
    [Graphical view]
    SMARTiSM00638. LPD_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF48431. SSF48431. 1 hit.
    SSF56968. SSF56968. 2 hits.
    PROSITEiPS51211. VITELLOGENIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7Z7Q0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDPPRPALLA LPALLLLLLA GARAEEEMLE NVSLVCPKDA TRFKHLRKYT    50
    YNYEAESSSG VPGTADSRSA TRINCKVELE VPQLCSFILK TSQCILKEVY 100
    GFNPEGKALL KKTKNSEEFA AAMSRYELKL AIPEGKQVFL YPEKDEPTYI 150
    LNIKRGIISA LLVPPETEEA KQVLFLDTVY GNCSTHFTVK TRKGNVATEI 200
    STERDLGQCD RFKPIRTGIS PLALIKGMTR PLSTLISSSQ SCQYTLDAKR 250
    KHVAEAICKE QHLFLPFSYK NKYGMVAQVT QTLKLEDTPK INSRFFGEGT 300
    KKMGLAFEST KSTSPPKQAE AVLKTLQELK KLTISEQNIQ RANLFNKLVT 350
    ELRGLSDEAV TSLLPQLIEV SSPITLQALV QCGQPQCSTH ILQWLKRVHA 400
    NPLLIDVVTY LVALIPEPSA QQLREIFNMA RDQRSRATLY ALSHAVNNYH 450
    KTNPTGTQEL LDIANYLMEQ IQDDCTGDED YTYLILRVIG NMGQTMEQLT 500
    PELKSSILKC VQSTKPSLMI QKAAIQALRK MEPKDKDQEV LLQTFLDDAS 550
    PGDKRLAAYL MLMRSPSQAD INKIVQILPW EQNEQVKNFV ASHIANILNS 600
    EELDIQDLKK LVKEALKESQ LPTVMDFRKF SRNYQLYKSV SLPSLDPASA 650
    KIEGNLIFDP NNYLPKESML KTTLTAFGFA SADLIEIGLE GKGFEPTLEA 700
    LFGKQGFFPD SVNKALYWVN GQVPDGVSKV LVDHFGYTKD DKHEQDMVNG 750
    IMLSVEKLIK DLKSKEVPEA RAYLRILGEE LGFASLHDLQ LLGKLLLMDR 800
    PDSLTIPAAQ ARKDACTFFR DGGLP 825
    Length:825
    Mass (Da):92,334
    Last modified:October 1, 2003 - v1
    Checksum:i9004A128F9E6338E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC051278 mRNA. Translation: AAH51278.1.
    RefSeqiNP_000375.2. NM_000384.2.
    UniGeneiHs.120759.

    Genome annotation databases

    GeneIDi338.
    KEGGihsa:338.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC051278 mRNA. Translation: AAH51278.1 .
    RefSeqi NP_000375.2. NM_000384.2.
    UniGenei Hs.120759.

    3D structure databases

    ProteinModelPortali Q7Z7Q0.
    ModBasei Search...

    Proteomic databases

    PRIDEi Q7Z7Q0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 338.
    KEGGi hsa:338.

    Organism-specific databases

    CTDi 338.
    PharmGKBi PA50.

    Phylogenomic databases

    HOVERGENi HBG066906.
    KOi K14462.

    Miscellaneous databases

    ChiTaRSi APOB. human.
    GenomeRNAii 338.
    NextBioi 1399.

    Family and domain databases

    Gene3Di 1.25.10.20. 1 hit.
    2.20.50.20. 2 hits.
    2.30.230.10. 1 hit.
    InterProi IPR015819. Lipid_transp_b-sht_shell.
    IPR001747. Lipid_transpt_N.
    IPR015816. Vitellinogen_b-sht_N.
    IPR015255. Vitellinogen_open_b-sht.
    IPR015817. Vitellinogen_open_b-sht_sub1.
    IPR011030. Vitellinogen_superhlx.
    [Graphical view ]
    Pfami PF09172. DUF1943. 1 hit.
    PF01347. Vitellogenin_N. 1 hit.
    [Graphical view ]
    SMARTi SM00638. LPD_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48431. SSF48431. 1 hit.
    SSF56968. SSF56968. 2 hits.
    PROSITEi PS51211. VITELLOGENIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: LiverImported.

    Entry informationi

    Entry nameiQ7Z7Q0_HUMAN
    AccessioniPrimary (citable) accession number: Q7Z7Q0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2003
    Last sequence update: October 1, 2003
    Last modified: January 22, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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