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Q7Z7N9

- T179B_HUMAN

UniProt

Q7Z7N9 - T179B_HUMAN

Protein

Transmembrane protein 179B

Gene

TMEM179B

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (01 Oct 2003)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transmembrane protein 179B
    Gene namesi
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:33744. TMEM179B.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA162405996.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 219219Transmembrane protein 179BPRO_0000328987Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei206 – 2061Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ7Z7N9.
    PaxDbiQ7Z7N9.
    PRIDEiQ7Z7N9.

    PTM databases

    PhosphoSiteiQ7Z7N9.

    Expressioni

    Gene expression databases

    ArrayExpressiQ7Z7N9.
    BgeeiQ7Z7N9.
    CleanExiHS_TMEM179B.
    GenevestigatoriQ7Z7N9.

    Organism-specific databases

    HPAiHPA016585.

    Interactioni

    Protein-protein interaction databases

    BioGridi131898. 2 interactions.
    MINTiMINT-7034562.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7Z7N9.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei9 – 2921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei65 – 8521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei96 – 11621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei167 – 18721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TMEM179 family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG41412.
    HOGENOMiHOG000154483.
    HOVERGENiHBG095581.
    InParanoidiQ7Z7N9.
    OMAiLFWVYSS.
    PhylomeDBiQ7Z7N9.
    TreeFamiTF324841.

    Family and domain databases

    InterProiIPR029776. TMEM179B.
    [Graphical view]
    PANTHERiPTHR31056:SF1. PTHR31056:SF1. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q7Z7N9-1 [UniParc]FASTAAdd to Basket

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    MALSWLQRVE LALFAAAFLC GAVAAAAMTR TQGSFSGRCP LYGVATLNGS    50
    SLALSRPSAP SLCYFVAGAS GLLALYCLLL LLFWIYSSCI EDSHRGAIGL 100
    RIALAISAIA VFLVLVSACI LRFGTRSLCN SIISLNTTIS CSEAQKIPWT 150
    PPGTALQFYS NLHNAETSSW VNLVLWCVVL VLQVVQWKSE ATPYRPLERG 200
    DPEWSSETDA LVGSRLSHS 219
    Length:219
    Mass (Da):23,550
    Last modified:October 1, 2003 - v1
    Checksum:i0D9EE5D760A0A10E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH471076 Genomic DNA. Translation: EAW74098.1.
    BC051355 mRNA. Translation: AAH51355.1.
    CCDSiCCDS8036.1.
    RefSeqiNP_955369.1. NM_199337.2.
    UniGeneiHs.381134.

    Genome annotation databases

    EnsembliENST00000333449; ENSP00000333697; ENSG00000185475.
    GeneIDi374395.
    KEGGihsa:374395.
    UCSCiuc001nvd.4. human.

    Polymorphism databases

    DMDMi74738902.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH471076 Genomic DNA. Translation: EAW74098.1 .
    BC051355 mRNA. Translation: AAH51355.1 .
    CCDSi CCDS8036.1.
    RefSeqi NP_955369.1. NM_199337.2.
    UniGenei Hs.381134.

    3D structure databases

    ProteinModelPortali Q7Z7N9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 131898. 2 interactions.
    MINTi MINT-7034562.

    PTM databases

    PhosphoSitei Q7Z7N9.

    Polymorphism databases

    DMDMi 74738902.

    Proteomic databases

    MaxQBi Q7Z7N9.
    PaxDbi Q7Z7N9.
    PRIDEi Q7Z7N9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000333449 ; ENSP00000333697 ; ENSG00000185475 .
    GeneIDi 374395.
    KEGGi hsa:374395.
    UCSCi uc001nvd.4. human.

    Organism-specific databases

    CTDi 374395.
    GeneCardsi GC11P062554.
    HGNCi HGNC:33744. TMEM179B.
    HPAi HPA016585.
    neXtProti NX_Q7Z7N9.
    PharmGKBi PA162405996.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG41412.
    HOGENOMi HOG000154483.
    HOVERGENi HBG095581.
    InParanoidi Q7Z7N9.
    OMAi LFWVYSS.
    PhylomeDBi Q7Z7N9.
    TreeFami TF324841.

    Miscellaneous databases

    ChiTaRSi TMEM179B. human.
    GenomeRNAii 374395.
    NextBioi 100178.
    PROi Q7Z7N9.

    Gene expression databases

    ArrayExpressi Q7Z7N9.
    Bgeei Q7Z7N9.
    CleanExi HS_TMEM179B.
    Genevestigatori Q7Z7N9.

    Family and domain databases

    InterProi IPR029776. TMEM179B.
    [Graphical view ]
    PANTHERi PTHR31056:SF1. PTHR31056:SF1. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Ovary.
    3. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-206, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.

    Entry informationi

    Entry nameiT179B_HUMAN
    AccessioniPrimary (citable) accession number: Q7Z7N9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 8, 2008
    Last sequence update: October 1, 2003
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 11
      Human chromosome 11: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3