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Protein

Uncharacterized protein C11orf96

Gene

C11orf96

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C11orf96
Alternative name(s):
Protein Ag2 homolog
Gene namesi
Name:C11orf96
Synonyms:AG2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:38675. C11orf96.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA165543281.

Polymorphism and mutation databases

BioMutaiC11orf96.
DMDMi229463005.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 435435Uncharacterized protein C11orf96PRO_0000320641Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei368 – 3681PhosphothreonineCombined sources
Modified residuei385 – 3851PhosphoserineBy similarity
Modified residuei399 – 3991PhosphoserineCombined sources
Modified residuei409 – 4091PhosphoserineBy similarity
Modified residuei425 – 4251PhosphoserineCombined sources
Modified residuei431 – 4311PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ7Z7L8.
PeptideAtlasiQ7Z7L8.
PRIDEiQ7Z7L8.

PTM databases

iPTMnetiQ7Z7L8.
PhosphoSiteiQ7Z7L8.

Expressioni

Gene expression databases

BgeeiQ7Z7L8.
ExpressionAtlasiQ7Z7L8. baseline and differential.
GenevisibleiQ7Z7L8. HS.

Organism-specific databases

HPAiHPA038843.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000340667.

Structurei

3D structure databases

ProteinModelPortaliQ7Z7L8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi242 – 30766Pro-richAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IYI1. Eukaryota.
ENOG4112BAS. LUCA.
GeneTreeiENSGT00390000016821.
InParanoidiQ7Z7L8.
PhylomeDBiQ7Z7L8.
TreeFamiTF337679.

Family and domain databases

InterProiIPR031521. DUF4695.
[Graphical view]
PfamiPF15766. DUF4695. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7Z7L8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNKQPQKVT VPTGTALQGV VLIVSTLHQP GGWICGKDPC CSLRPLSNSV
60 70 80 90 100
QNALACKSKQ DYQAGILFKT RAFISRDCGS DAAEDSASKG ETYTLTLEHK
110 120 130 140 150
GAGEGDLRPR GQPGWCRLGD PRRDSARPVA AIEGPCPGAA RASRVLRGRG
160 170 180 190 200
FSRNPRGRGL PSGAGWRGAG GAGEGAVTFP ERRGDVRRKG AGRARFKWHS
210 220 230 240 250
LSSELRAVWA AAGYISREPG RRGADGDSSG GERLGARRNS APRAPCPPTG
260 270 280 290 300
PPARPPSRGA PARAREGRRH PAADLDPPPG EPPAAASRGA PAQRPPSESP
310 320 330 340 350
GAPPPGPADA GGAMAAKPGE LMGICSSYQA VMPHFVCLAD EFPQPVRPAK
360 370 380 390 400
LPKGRGRLRR PRQSRFKTQP VTFDEIQEVE EEGVSPMEEE KAKKSFLQSL
410 420 430
ECLRRSTQSL SLQREQLSSC KLRNSLDSSD SDSAL
Length:435
Mass (Da):46,114
Last modified:May 5, 2009 - v3
Checksum:iF536980973B14478
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti26 – 261T → A.
Corresponds to variant rs1973717 [ dbSNP | Ensembl ].
VAR_039242
Natural varianti47 – 471S → P.
Corresponds to variant rs12797684 [ dbSNP | Ensembl ].
VAR_039243
Natural varianti110 – 1101R → S.
Corresponds to variant rs12796438 [ dbSNP | Ensembl ].
VAR_039244
Natural varianti144 – 1441R → C.
Corresponds to variant rs12796667 [ dbSNP | Ensembl ].
VAR_039245
Natural varianti151 – 1511F → S.
Corresponds to variant rs12798337 [ dbSNP | Ensembl ].
VAR_039246
Natural varianti352 – 3521P → S.
Corresponds to variant rs2434483 [ dbSNP | Ensembl ].
VAR_039247

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087521 Genomic DNA. No translation available.
BC052560 mRNA. Translation: AAH52560.1.
RefSeqiNP_001138505.1. NM_001145033.1.
UniGeneiHs.530443.

Genome annotation databases

EnsembliENST00000339446; ENSP00000340667; ENSG00000187479.
GeneIDi387763.
KEGGihsa:387763.
UCSCiuc058aps.1. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087521 Genomic DNA. No translation available.
BC052560 mRNA. Translation: AAH52560.1.
RefSeqiNP_001138505.1. NM_001145033.1.
UniGeneiHs.530443.

3D structure databases

ProteinModelPortaliQ7Z7L8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000340667.

PTM databases

iPTMnetiQ7Z7L8.
PhosphoSiteiQ7Z7L8.

Polymorphism and mutation databases

BioMutaiC11orf96.
DMDMi229463005.

Proteomic databases

PaxDbiQ7Z7L8.
PeptideAtlasiQ7Z7L8.
PRIDEiQ7Z7L8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000339446; ENSP00000340667; ENSG00000187479.
GeneIDi387763.
KEGGihsa:387763.
UCSCiuc058aps.1. human.

Organism-specific databases

CTDi387763.
GeneCardsiC11orf96.
H-InvDBHIX0035967.
HIX0171336.
HGNCiHGNC:38675. C11orf96.
HPAiHPA038843.
neXtProtiNX_Q7Z7L8.
PharmGKBiPA165543281.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IYI1. Eukaryota.
ENOG4112BAS. LUCA.
GeneTreeiENSGT00390000016821.
InParanoidiQ7Z7L8.
PhylomeDBiQ7Z7L8.
TreeFamiTF337679.

Miscellaneous databases

ChiTaRSiC11orf96. human.
GenomeRNAii387763.
PROiQ7Z7L8.

Gene expression databases

BgeeiQ7Z7L8.
ExpressionAtlasiQ7Z7L8. baseline and differential.
GenevisibleiQ7Z7L8. HS.

Family and domain databases

InterProiIPR031521. DUF4695.
[Graphical view]
PfamiPF15766. DUF4695. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 209-435.
    Tissue: Salivary gland.
  3. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-425, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-399 AND SER-425, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Erythroleukemia.
  5. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-368, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.

Entry informationi

Entry nameiCK096_HUMAN
AccessioniPrimary (citable) accession number: Q7Z7L8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: May 5, 2009
Last modified: July 6, 2016
This is version 78 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.