Q7Z7H8A6NGJ4Q96B80Q96Q55RM10_HUMANLarge ribosomal subunit protein uL10m39S ribosomal protein L10, mitochondrialL10mtMRP-L1039S ribosomal protein L8, mitochondrialL8mtMRP-L8MRPL10MRPL8RPML8Homo sapiensHumanEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomoComplete sequencing and characterization of 21,243 full-length human cDNAs.NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)VARIANT ILE-125The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 235-261The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present.IDENTIFICATIONInitial characterization of the human central proteome.IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]N-terminome analysis of the human mitochondrial proteome.IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]Structure of the large ribosomal subunit from human mitochondria.STRUCTURE BY ELECTRON MICROSCOPY (3.40 ANGSTROMS)SUBCELLULAR LOCATIONSUBUNITRibosome. The structure of the human mitochondrial ribosome.STRUCTURE BY ELECTRON MICROSCOPY (3.50 ANGSTROMS)SUBCELLULAR LOCATIONSUBUNITStructures of the human mitochondrial ribosome in native states of assembly.STRUCTURE BY ELECTRON MICROSCOPY (3.03 ANGSTROMS)SUBCELLULAR LOCATIONSUBUNITExome Sequencing and Linkage Analysis Identified Novel Candidate Genes in Recessive Intellectual Disability Associated with Ataxia.VARIANT TRP-166Component of the mitochondrial large ribosomal subunit (mt-LSU) (PubMed:28892042, PubMed:25838379, PubMed:25278503). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins. uL10m contributes a single cysteine residue to a zinc-binding site with mL66.Q7Z7H8P35609false3Q7Z7H8Q8IZU0false3Q7Z7H8Q53G59false3Q7Z7H8Q8ND90false3Q7Z7H8Q04864false3Q7Z7H8P15884false3MitochondrionQ7Z7H8-11Q7Z7H8-22Belongs to the universal ribosomal protein uL10 family.3D-structureAlternative splicingMitochondrionReference proteomeRibonucleoproteinRibosomal proteinTransit peptideMAAAVAGMLRGGLLPQAMISAHCNLHLPGSSDSPASASQVAGITVIRWMAAAVAGMLRGGLLPQAGRLPTLQTVRYGSKAVTRHRRVMHFQRQKLMAVTEYIPPKPAIHPSCLPSPPSPPQEEIGLIRLLRREIAAVFQDNRMIAVCQNVALSAEDKLLMRHQLRKHKILMKVFPNQVLKPFLEDSKYQNLLPLFVGHNMLLVSEEPKVKEMVRILRTVPFLPLLGGCIDDTILSRQGFINYSKLPSLPLVQGELVGGLTCLTAQTHSLLQHQPLQLTTLLDQYIREQREKDSVMSANGKPDPDTVPDS
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