Q7Z7B0 (FLIP1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Filamin-A-interacting protein 1
Short name=FILIP

Gene names

Name:	FILIP1
Synonyms:	KIAA1275

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1213 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A By similarity.
Subunit structure	Interacts with FLNA By similarity.
Tissue specificity	Moderately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus. Ref.7
Sequence similarities	Belongs to the FILIP1 family.
Sequence caution	The sequence BAA91763.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence CAH71818.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAH73614.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Coiled coil
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q7Z7B0-1)

Also known as: L-FILIP;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q7Z7B0-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1165-1213: GMKAGKPVVAAPGAGNLTKFEPRAETQSMKIELKKSAASSTTSLGGGKG → ESIIIHQLRMNSR

Note: No experimental confirmation available.

Isoform 3 (identifier: Q7Z7B0-3)

Also known as: S-FILIP;

The sequence of this isoform differs from the canonical sequence as follows:
     1-248: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1213	1213	Filamin-A-interacting protein 1		PRO_0000234540
Regions
	Coiled coil	192 – 591	400	Potential
	Coiled coil	624 – 781	158	Potential
	Compositional bias	37 – 41	5	Poly-Lys
Natural variations
	Alternative sequence	1 – 248	248	Missing in isoform 3.		VSP_018344
	Alternative sequence	1165 – 1213	49	GMKAG…GGGKG → ESIIIHQLRMNSR in isoform 2.		VSP_018345
	Natural variant	1003	1	P → S. Corresponds to variant rs34807169 [ dbSNP | Ensembl ].		VAR_050995
Experimental info
	Sequence conflict	40	1	K → R in CAD89912. Ref.3
	Sequence conflict	74 – 90	17	ELSKE…IMEGE → AQYAIYIVSRLILLHFL in BAA86589. Ref.2
	Sequence conflict	348	1	T → I in CAD89912. Ref.3
	Sequence conflict	373	1	N → D in BX647178. Ref.3
	Sequence conflict	421	1	L → F in BAC04928. Ref.2
	Sequence conflict	723	1	E → G in BAB55310. Ref.2
	Sequence conflict	793	1	R → K in BAB55310. Ref.2
	Sequence conflict	1045	1	T → A in BX647178. Ref.3
	Sequence conflict	1102	1	E → G in CAD89912. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 (L-FILIP) [UniParc]. Last modified October 1, 2003. Version 1. Checksum: EE4329B03516E6AF	FASTA	1,213	138,109
	10 20 30 40 50 60 MRSRNQGGES ASDGHISCPK PSIIGNAGEK SLSEDAKKKK KSNRKEDDVM ASGTVKRHLK 70 80 90 100 110 120 TSGECERKTK KSLELSKEDL IQLLSIMEGE LQAREDVIHM LKTEKTKPEV LEAHYGSAEP 130 140 150 160 170 180 EKVLRVLHRD AILAQEKSIG EDVYEKPISE LDRLEEKQKE TYRRMLEQLL LAEKCHRRTV 190 200 210 220 230 240 YELENEKHKH TDYMNKSDDF TNLLEQERER LKKLLEQEKA YQARKEKENA KRLNKLRDEL 250 260 270 280 290 300 VKLKSFALML VDERQMHIEQ LGLQSQKVQD LTQKLREEEE KLKAITSKSK EDRQKLLKLE 310 320 330 340 350 360 VDFEHKASRF SQEHEEMNAK LANQESHNRQ LRLKLVGLTQ RIEELEETNK NLQKAEEELQ 370 380 390 400 410 420 ELRDKIAKGE CGNSSLMAEV ENLRKRVLEM EGKDEEITKT ESQCRELRKK LQEEEHHSKE 430 440 450 460 470 480 LRLEVEKLQK RMSELEKLEE AFSKSKSECT QLHLNLEKEK NLTKDLLNEL EVVKSRVKEL 490 500 510 520 530 540 ECSESRLEKA ELSLKDDLTK LKSFTVMLVD ERKNMMEKIK QEERKVDGLN KNFKVEQGKV 550 560 570 580 590 600 MDVTEKLIEE SKKLLKLKSE MEEKVYNLTR ERDELIGKLK SEEEKSSELS CSVDLLKKRL 610 620 630 640 650 660 DGIEEVEREI TRGRSRKGSE LTCPEDNKIK ELTLEIERLK KRLQQLEVVE GDLMKTEDEY 670 680 690 700 710 720 DQLEQKFRTE QDKANFLSQQ LEEIKHQIAK NKAIEKGEVV SQEAELRHRF RLEEAKSRDL 730 740 750 760 770 780 KAEVQALKEK IHELMNKEDQ LSQLQVDYSV LQQRFMEEEN KNKNMGQEVL NLTKELELSK 790 800 810 820 830 840 RYSRALRPSV NGRRMVDVPV TSTGVQTDAV SGEAAEEETP AVFIRKSFQE ENHIMSNLRQ 850 860 870 880 890 900 VGLKKPVERS SVLDRYPPAA NELTMRKSWI PWMRKRENGP SITQEKGPRT NSSPGHPGEV 910 920 930 940 950 960 VLSPKQGQPL HIRVTPDHEN STATLEITSP TSEEFFSSTT VIPTLGNQKP RITIIPSPNV 970 980 990 1000 1010 1020 MPQKQKSGDT TLGPERAMSP VTITTFSREK TPESGRGAFA DRPTSPIQIM TVSTSAAPAE 1030 1040 1050 1060 1070 1080 IAVSPESQEM PMGRTILKVT PEKQTVPTPV RKYNSNANII TTEDNKIHIH LGSQFKRSPG 1090 1100 1110 1120 1130 1140 TSGEGVSPVI TVRPVNVTAE KEVSTGTVLR SPRNHLSSRP GASKVTSTIT ITPVTTSSAR 1150 1160 1170 1180 1190 1200 GTQSVSGQDG SSQRPTPTRI PMSKGMKAGK PVVAAPGAGN LTKFEPRAET QSMKIELKKS 1210 AASSTTSLGG GKG
	Isoform 2 [UniParc]. Checksum: BF9EC236362CE6B4	FASTA	1,177	134,859
	10 20 30 40 50 60 MRSRNQGGES ASDGHISCPK PSIIGNAGEK SLSEDAKKKK KSNRKEDDVM ASGTVKRHLK 70 80 90 100 110 120 TSGECERKTK KSLELSKEDL IQLLSIMEGE LQAREDVIHM LKTEKTKPEV LEAHYGSAEP 130 140 150 160 170 180 EKVLRVLHRD AILAQEKSIG EDVYEKPISE LDRLEEKQKE TYRRMLEQLL LAEKCHRRTV 190 200 210 220 230 240 YELENEKHKH TDYMNKSDDF TNLLEQERER LKKLLEQEKA YQARKEKENA KRLNKLRDEL 250 260 270 280 290 300 VKLKSFALML VDERQMHIEQ LGLQSQKVQD LTQKLREEEE KLKAITSKSK EDRQKLLKLE 310 320 330 340 350 360 VDFEHKASRF SQEHEEMNAK LANQESHNRQ LRLKLVGLTQ RIEELEETNK NLQKAEEELQ 370 380 390 400 410 420 ELRDKIAKGE CGNSSLMAEV ENLRKRVLEM EGKDEEITKT ESQCRELRKK LQEEEHHSKE 430 440 450 460 470 480 LRLEVEKLQK RMSELEKLEE AFSKSKSECT QLHLNLEKEK NLTKDLLNEL EVVKSRVKEL 490 500 510 520 530 540 ECSESRLEKA ELSLKDDLTK LKSFTVMLVD ERKNMMEKIK QEERKVDGLN KNFKVEQGKV 550 560 570 580 590 600 MDVTEKLIEE SKKLLKLKSE MEEKVYNLTR ERDELIGKLK SEEEKSSELS CSVDLLKKRL 610 620 630 640 650 660 DGIEEVEREI TRGRSRKGSE LTCPEDNKIK ELTLEIERLK KRLQQLEVVE GDLMKTEDEY 670 680 690 700 710 720 DQLEQKFRTE QDKANFLSQQ LEEIKHQIAK NKAIEKGEVV SQEAELRHRF RLEEAKSRDL 730 740 750 760 770 780 KAEVQALKEK IHELMNKEDQ LSQLQVDYSV LQQRFMEEEN KNKNMGQEVL NLTKELELSK 790 800 810 820 830 840 RYSRALRPSV NGRRMVDVPV TSTGVQTDAV SGEAAEEETP AVFIRKSFQE ENHIMSNLRQ 850 860 870 880 890 900 VGLKKPVERS SVLDRYPPAA NELTMRKSWI PWMRKRENGP SITQEKGPRT NSSPGHPGEV 910 920 930 940 950 960 VLSPKQGQPL HIRVTPDHEN STATLEITSP TSEEFFSSTT VIPTLGNQKP RITIIPSPNV 970 980 990 1000 1010 1020 MPQKQKSGDT TLGPERAMSP VTITTFSREK TPESGRGAFA DRPTSPIQIM TVSTSAAPAE 1030 1040 1050 1060 1070 1080 IAVSPESQEM PMGRTILKVT PEKQTVPTPV RKYNSNANII TTEDNKIHIH LGSQFKRSPG 1090 1100 1110 1120 1130 1140 TSGEGVSPVI TVRPVNVTAE KEVSTGTVLR SPRNHLSSRP GASKVTSTIT ITPVTTSSAR 1150 1160 1170 GTQSVSGQDG SSQRPTPTRI PMSKESIIIH QLRMNSR
	Isoform 3 (S-FILIP) [UniParc]. Checksum: 75A68B5C76E5E62E	FASTA	965	109,300
	10 20 30 40 50 60 MLVDERQMHI EQLGLQSQKV QDLTQKLREE EEKLKAITSK SKEDRQKLLK LEVDFEHKAS 70 80 90 100 110 120 RFSQEHEEMN AKLANQESHN RQLRLKLVGL TQRIEELEET NKNLQKAEEE LQELRDKIAK 130 140 150 160 170 180 GECGNSSLMA EVENLRKRVL EMEGKDEEIT KTESQCRELR KKLQEEEHHS KELRLEVEKL 190 200 210 220 230 240 QKRMSELEKL EEAFSKSKSE CTQLHLNLEK EKNLTKDLLN ELEVVKSRVK ELECSESRLE 250 260 270 280 290 300 KAELSLKDDL TKLKSFTVML VDERKNMMEK IKQEERKVDG LNKNFKVEQG KVMDVTEKLI 310 320 330 340 350 360 EESKKLLKLK SEMEEKVYNL TRERDELIGK LKSEEEKSSE LSCSVDLLKK RLDGIEEVER 370 380 390 400 410 420 EITRGRSRKG SELTCPEDNK IKELTLEIER LKKRLQQLEV VEGDLMKTED EYDQLEQKFR 430 440 450 460 470 480 TEQDKANFLS QQLEEIKHQI AKNKAIEKGE VVSQEAELRH RFRLEEAKSR DLKAEVQALK 490 500 510 520 530 540 EKIHELMNKE DQLSQLQVDY SVLQQRFMEE ENKNKNMGQE VLNLTKELEL SKRYSRALRP 550 560 570 580 590 600 SVNGRRMVDV PVTSTGVQTD AVSGEAAEEE TPAVFIRKSF QEENHIMSNL RQVGLKKPVE 610 620 630 640 650 660 RSSVLDRYPP AANELTMRKS WIPWMRKREN GPSITQEKGP RTNSSPGHPG EVVLSPKQGQ 670 680 690 700 710 720 PLHIRVTPDH ENSTATLEIT SPTSEEFFSS TTVIPTLGNQ KPRITIIPSP NVMPQKQKSG 730 740 750 760 770 780 DTTLGPERAM SPVTITTFSR EKTPESGRGA FADRPTSPIQ IMTVSTSAAP AEIAVSPESQ 790 800 810 820 830 840 EMPMGRTILK VTPEKQTVPT PVRKYNSNAN IITTEDNKIH IHLGSQFKRS PGTSGEGVSP 850 860 870 880 890 900 VITVRPVNVT AEKEVSTGTV LRSPRNHLSS RPGASKVTST ITITPVTTSS ARGTQSVSGQ 910 920 930 940 950 960 DGSSQRPTPT RIPMSKGMKA GKPVVAAPGA GNLTKFEPRA ETQSMKIELK KSAASSTTSL GGGKG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Human orthologue of L-FILIP." Nagano T., Sato M. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 550-1213 (ISOFORM 3). Tissue: Small intestine.
[3]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2). Tissue: Skeletal muscle and Small intestine.
[4]	"The DNA sequence and analysis of human chromosome 6." Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S. Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
[7]	"Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Ishikawa K., Kikuno R., Hirosawa M., Nomura N., Ohara O. DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 74-1213 (ISOFORM 1), TISSUE SPECIFICITY. Tissue: Brain.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB086011 mRNA. Translation: BAC77067.1. AK001570 mRNA. Translation: BAA91763.1. Different initiation. AK027705 mRNA. Translation: BAB55310.1. AK097021 mRNA. Translation: BAC04928.1. AL832009 mRNA. Translation: CAD89912.1. BX647178 mRNA. No translation available. AL589649, AL445465 Genomic DNA. Translation: CAH71818.1. Sequence problems. AL589649, AL445465 Genomic DNA. Translation: CAH71820.1. AL445465, AL589649 Genomic DNA. Translation: CAH73614.1. Sequence problems. AL445465, AL589649 Genomic DNA. Translation: CAH73615.1. CH471051 Genomic DNA. Translation: EAW48737.1. BC136443 mRNA. Translation: AAI36444.1. BC136444 mRNA. Translation: AAI36445.1. AB033101 mRNA. Translation: BAA86589.1.
IPI	IPI00297210. IPI00642180. IPI00745798.
RefSeq	NP_056502.1. NM_015687.2.
UniGene	Hs.696158.
3D structure databases
ProteinModelPortal	Q7Z7B0.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000237172.
PTM databases
PhosphoSite	Q7Z7B0.
Polymorphism databases
DMDM	74750226.
Proteomic databases
PaxDb	Q7Z7B0.
PRIDE	Q7Z7B0.
Protocols and materials databases
DNASU	27145.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000237172; ENSP00000237172; ENSG00000118407. ENST00000370020; ENSP00000359037; ENSG00000118407. ENST00000393004; ENSP00000376728; ENSG00000118407.
GeneID	27145.
KEGG	hsa:27145.
UCSC	uc003phy.1. human. uc003phz.3. human.
Organism-specific databases
CTD	27145.
GeneCards	GC06M076005.
HGNC	HGNC:21015. FILIP1.
MIM	607307. gene.
neXtProt	NX_Q7Z7B0.
PharmGKB	PA134992638.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG145980.
HOVERGEN	HBG053840.
InParanoid	Q7Z7B0.
OMA	DERKNMM.
OrthoDB	EOG4GTKC7.
PhylomeDB	Q7Z7B0.
Gene expression databases
Bgee	Q7Z7B0.
CleanEx	HS_FILIP1.
Genevestigator	Q7Z7B0.
GermOnline	ENSG00000118407. Homo sapiens.
Family and domain databases
InterPro	IPR019131. Cortactin-binding_p2_N. [Graphical view]
Pfam	PF09727. CortBP2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	27145.
NextBio	49894.
SOURCE	Search...

Entry information

Entry name

FLIP1_HUMAN

Accession

Primary (citable) accession number: Q7Z7B0
Secondary accession number(s): B2RMU6 , Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
Last sequence update:	October 1, 2003
Last modified:	April 3, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.