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Protein
Submitted name:

Myosin 5B

Gene

MYO5B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi162 – 169ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotationSAAS annotation, Motor protein, MyosinPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Myosin 5BImported
Gene namesi
Name:MYO5BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000167306.18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31408

PTM / Processingi

Proteomic databases

MaxQBiQ7Z7A5
PeptideAtlasiQ7Z7A5

Expressioni

Gene expression databases

BgeeiENSG00000167306

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ7Z7A5
SMRiQ7Z7A5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0160 Eukaryota
KOG0161 Eukaryota
COG5022 LUCA
HOVERGENiHBG105641
KOiK10357

Family and domain databases

CDDicd01380 MYSc_Myo5, 1 hit
Gene3Di2.30.30.360, 1 hit
3.40.850.10, 2 hits
InterProiView protein in InterPro
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR008989 Myosin_S1_N
IPR036103 MYSc_Myo5
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00063 Myosin_head, 1 hit
PRINTSiPR00193 MYOSINHEAVY
SMARTiView protein in SMART
SM00242 MYSc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51456 MYOSIN_MOTOR, 1 hit

Sequencei

Sequence statusi: Complete.

Q7Z7A5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHWPVTRECT RVWIPDPDEV WRSAELTKDY KEGDKSLQLR LEDETILEYP
60 70 80 90 100
IDVQRNQLPF LRNPDILVGE NDLTALSYLH EPAVLHNLKV RFLESNHIYT
110 120 130 140 150
YCGIVLVAIN PYEQLPIYGQ DVIYTYSGQN MGDMDPHIFA VAEEAYKQMA
160 170 180 190 200
RDEKNQSIIV SGESGAGKTV SAKYAMRYFA TVGGSASETN IEEKVLASSP
210 220 230 240 250
IMEAIGNAKT TRNDNSSRFG KYIQIGFDKR YHIIGANMRT YLLEKSRVVF
260 270 280 290 300
QADDERNYHI FYQLCAAAGL PEFKELALTS AEDFFYTSQG GDTSIEGVDD
310 320 330 340 350
AEDFEKTRQA FTLLGVKESH QMSIFKIIAS ILHLGSVAIQ AERDGDSCSI
360 370 380 390 400
SPQDVYLSNF CRLLGVEHSQ MEHWLCHRKL VTTSETYVKT MSLQQVINAR
410 420 430 440 450
NALAKHIYAQ LFGWIVEHIN KALHTSLKQH SFIGVLDIYG FETFEVNSFE
460 470 480 490 500
QFCINYANEK LQQQFNSHVF KLEQEEYMKE QIPWTLIDFY DNQPCIDLIE
510 520 530 540 550
AKLGILDLLD EECKVPKGTD QNWAQKLYDR HSSSQHFQKP RMSNTAFIIV
560 570 580 590 600
HFADKVEYLS DGFLEKNRDT VYEEQINILK ASKFPLVADL FHDDKDPVPA
610 620 630 640 650
TTPGKGSSSK ISVRSARPPM KVSNKEHKKT VGHQFRTSLS TQQIVKILNL
660 670 680 690 700
YTPLNEFEER VTVAFIRTIQ AQLQERNDPQ QLLLDAKHMF PVLFPFNPSS
710 720
LTMDSIHIPA CLNLEFLNEV
Length:720
Mass (Da):82,405
Last modified:October 1, 2003 - v1
Checksum:i029C482A99C68E73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY274809 mRNA Translation: AAP42074.1
RefSeqiNP_001073936.1, NM_001080467.2
UniGeneiHs.720076

Genome annotation databases

GeneIDi4645
KEGGihsa:4645
UCSCiuc060pcq.1 human

Similar proteinsi

Entry informationi

Entry nameiQ7Z7A5_HUMAN
AccessioniPrimary (citable) accession number: Q7Z7A5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: April 25, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health