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Protein
Submitted name:

CCT8 protein

Gene

CCT8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ChaperoneUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
CCT8 proteinImported
Submitted name:
Chaperonin containing TCP1, subunit 8 (Theta), isoform CRA_cImported
Gene namesi
Name:CCT8Imported
ORF Names:hCG_1810843Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotation

PTM / Processingi

Proteomic databases

PeptideAtlasiQ7Z759.

Expressioni

Gene expression databases

BgeeiENSG00000156261.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000286788.

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0362. Eukaryota.
ENOG410XPXR. LUCA.
HOVERGENiHBG103107.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.30.260.10. 2 hits.
3.50.7.10. 1 hit.
InterProiIPR012721. Chap_CCT_theta.
IPR017998. Chaperone_TCP-1.
IPR002194. Chaperonin_TCP-1_CS.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
[Graphical view]
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00304. TCOMPLEXTCP1.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02346. chap_CCT_theta. 1 hit.
PROSITEiPS00751. TCP1_2. 1 hit.
PS00995. TCP1_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7Z759-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKMVINHLE KLFVTNDAAT ILRELEVQHP AAKMIVMASH MQEQEVGDGT
60 70 80 90 100
NFVLVFAGAL LELAEELLRI GLSVSEVIEG YEIACRKAHE ILPNLVCCSA
110 120 130 140 150
KNLRDIDEVS SLLRTSIMSK QYGNEVFLAK LIAQACVSIF PDSGHFNVDN
160 170 180 190 200
IRVCKILGSG ISSSSVLHGM VFKKETEGDV TSVKDAKIAV YSCPFDGMIT
210 220 230 240 250
ETKGTVLIKT AEELMNFSKG EENLMDAQVK AIADTGANVV VTGGKVADMA
260 270 280 290 300
LHYANKYNIM LVRLNSKWDL RRLCKTVGAT ALPRLTPPVL EEMGHCDSVY
310 320 330 340 350
LSEVGDTQVV VFKHEKEDGA ISTIVLRGST DNLMDDIERA VDDGVNTFKV
360 370 380 390 400
LTRDKRLVPG GGATEIELAK QITSYGETCP GLEQYAIKKF AEAFEAIPRA
410 420 430 440 450
LAENSGVKAN EVISKLYAVH QEGNKNVGLD IEAEVPAVKD MLEAGILDTY
460 470 480 490
LGKYWAIKLA TNAAVTVLRV DQIIMAKPAG GPKPPSGKKD WDDDQND
Length:497
Mass (Da):54,106
Last modified:October 1, 2003 - v1
Checksum:i67A4ED7066DB3882
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC012584 mRNA. Translation: AAH12584.1.
CH471079 Genomic DNA. Translation: EAX09926.1.
RefSeqiNP_001269837.1. NM_001282908.1.
UniGeneiHs.125113.

Genome annotation databases

GeneIDi10694.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC012584 mRNA. Translation: AAH12584.1.
CH471079 Genomic DNA. Translation: EAX09926.1.
RefSeqiNP_001269837.1. NM_001282908.1.
UniGeneiHs.125113.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000286788.

Proteomic databases

PeptideAtlasiQ7Z759.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10694.

Organism-specific databases

CTDi10694.

Phylogenomic databases

eggNOGiKOG0362. Eukaryota.
ENOG410XPXR. LUCA.
HOVERGENiHBG103107.

Miscellaneous databases

ChiTaRSiCCT8. human.
GenomeRNAii10694.

Gene expression databases

BgeeiENSG00000156261.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.30.260.10. 2 hits.
3.50.7.10. 1 hit.
InterProiIPR012721. Chap_CCT_theta.
IPR017998. Chaperone_TCP-1.
IPR002194. Chaperonin_TCP-1_CS.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
[Graphical view]
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00304. TCOMPLEXTCP1.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02346. chap_CCT_theta. 1 hit.
PROSITEiPS00751. TCP1_2. 1 hit.
PS00995. TCP1_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ7Z759_HUMAN
AccessioniPrimary (citable) accession number: Q7Z759
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: September 7, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.