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Protein
Submitted name:

CCT8 protein

Gene

CCT8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
CCT8 proteinImported
Submitted name:
Chaperonin containing TCP1, subunit 8 (Theta), isoform CRA_cImported
Gene namesi
Name:CCT8Imported
ORF Names:hCG_1810843Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0362 Eukaryota
ENOG410XPXR LUCA
HOVERGENiHBG103107

Family and domain databases

CDDicd03341 TCP1_theta, 1 hit
Gene3Di1.10.560.102 hits
3.30.260.102 hits
3.50.7.101 hit
InterProiView protein in InterPro
IPR012721 Chap_CCT_theta
IPR017998 Chaperone_TCP-1
IPR002194 Chaperonin_TCP-1_CS
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PANTHERiPTHR11353 PTHR11353, 1 hit
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00304 TCOMPLEXTCP1
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 2 hits
TIGRFAMsiTIGR02346 chap_CCT_theta, 1 hit
PROSITEiView protein in PROSITE
PS00751 TCP1_2, 1 hit
PS00995 TCP1_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q7Z759-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKMVINHLE KLFVTNDAAT ILRELEVQHP AAKMIVMASH MQEQEVGDGT
60 70 80 90 100
NFVLVFAGAL LELAEELLRI GLSVSEVIEG YEIACRKAHE ILPNLVCCSA
110 120 130 140 150
KNLRDIDEVS SLLRTSIMSK QYGNEVFLAK LIAQACVSIF PDSGHFNVDN
160 170 180 190 200
IRVCKILGSG ISSSSVLHGM VFKKETEGDV TSVKDAKIAV YSCPFDGMIT
210 220 230 240 250
ETKGTVLIKT AEELMNFSKG EENLMDAQVK AIADTGANVV VTGGKVADMA
260 270 280 290 300
LHYANKYNIM LVRLNSKWDL RRLCKTVGAT ALPRLTPPVL EEMGHCDSVY
310 320 330 340 350
LSEVGDTQVV VFKHEKEDGA ISTIVLRGST DNLMDDIERA VDDGVNTFKV
360 370 380 390 400
LTRDKRLVPG GGATEIELAK QITSYGETCP GLEQYAIKKF AEAFEAIPRA
410 420 430 440 450
LAENSGVKAN EVISKLYAVH QEGNKNVGLD IEAEVPAVKD MLEAGILDTY
460 470 480 490
LGKYWAIKLA TNAAVTVLRV DQIIMAKPAG GPKPPSGKKD WDDDQND
Length:497
Mass (Da):54,106
Last modified:October 1, 2003 - v1
Checksum:i67A4ED7066DB3882
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC012584 mRNA Translation: AAH12584.1
CH471079 Genomic DNA Translation: EAX09926.1
RefSeqiNP_001269837.1, NM_001282908.1
UniGeneiHs.125113

Genome annotation databases

GeneIDi10694

Similar proteinsi

Entry informationi

Entry nameiQ7Z759_HUMAN
AccessioniPrimary (citable) accession number: Q7Z759
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: April 25, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.