POLR3A

Functionⁱ

GO - Molecular functionⁱ

DNA binding Source: InterPro
DNA-directed 5'-3' RNA polymerase activity Source: InterPro

GO - Biological processⁱ

transcription, DNA-templated Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: DNA-directed RNA polymerase III subunit RPC1Imported Submitted name: POLR3A proteinImported
Gene namesⁱ	Name:POLR3AImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 10

Organism-specific databases

HGNCⁱ

HGNC:30074. POLR3A.

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000148606.

OpenTargetsⁱ

ENSG00000148606.

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q7Z755.

MaxQBⁱ

Q7Z755.

Expressionⁱ

Gene expression databases

ExpressionAtlasⁱ	Q7Z755. baseline and differential.

ExpressionAtlasⁱ

Q7Z755. baseline and differential.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	15 – 131	RNA_pol_Rpb1_5InterPro annotationAdd BLAST		117

Phylogenomic databases

eggNOGⁱ	KOG0260. Eukaryota. COG0086. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00850000132392.

Family and domain databases

InterProⁱ	View protein in InterPro IPR007081. RNA_pol_Rpb1_5.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04998. RNA_pol_Rpb1_5. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q7Z755-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MYYVLQFLKE DLPKVVVQGI PEVSRAVIHI DEQSGKEKYK LLVEGDNLRA 
        60         70         80         90        100
VMATHGVKGT RTTSNNTYEV EKTLGIEAAR TTIINEIQYT MVNHGMSIDR 
       110        120        130        140        150
RHVMLLSDLM TYKGEVLGIT RFGLAKMKES VLMLASFEKT ADHLFDAAYF 
       160 
GQKDSVCAWP QP

Length:162

Mass (Da):18,272

Last modified:October 1, 2003 - v1

Checksum:ⁱ419894ED894ECC0D

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL391421 Genomic DNA. No translation available. AL512628 Genomic DNA. No translation available. BC014399 mRNA. Translation: AAH14399.1.
UniGeneⁱ	Hs.436896.

Genome annotation databases

Ensemblⁱ	ENST00000616246; ENSP00000483738; ENSG00000148606.
UCSC genome browser More...UCSCⁱ	uc057ujx.1. human.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL391421 Genomic DNA. No translation available. AL512628 Genomic DNA. No translation available. BC014399 mRNA. Translation: AAH14399.1.
UniGeneⁱ	Hs.436896.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q7Z755.

MaxQBⁱ

Q7Z755.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000616246; ENSP00000483738; ENSG00000148606.
UCSC genome browser More...UCSCⁱ	uc057ujx.1. human.

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:30074. POLR3A.
Open Targets More...OpenTargetsⁱ	ENSG00000148606.
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0260. Eukaryota. COG0086. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00850000132392.

Miscellaneous databases

ChiTaRSⁱ	POLR3A. human.

ChiTaRSⁱ

POLR3A. human.

Gene expression databases

ExpressionAtlasⁱ	Q7Z755. baseline and differential.

ExpressionAtlasⁱ

Q7Z755. baseline and differential.

Family and domain databases

InterProⁱ	View protein in InterPro IPR007081. RNA_pol_Rpb1_5.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04998. RNA_pol_Rpb1_5. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q7Z755_HUMAN
Accessionⁱ	Q7Z755Primary (citable) accession number: Q7Z755
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 1, 2003
	Last sequence update:	October 1, 2003
	Last modified:	July 5, 2017
	This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB - Q7Z755 (Q7Z755_HUMAN)

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DNA-directed RNA polymerase III subunit RPC1

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Organism-specific databases

Pathology & Biotechⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q7Z755 (Q7Z755_HUMAN)

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DNA-directed RNA polymerase III subunit RPC1

POLR3A

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ