Skip Header

Contribute Send feedback
Read comments (0) or add your own

Unreviewed, UniProtKB/TrEMBL Q7Z727 (Q7Z727_HUMAN)

Last modified February 9, 2010. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Hide | Top

Names and origin

Protein namesSubmitted name:
    PRKCA protein EMBL AAH53321.1
Gene names
Name: PRKCA EMBL AAH53321.1
OrganismHomo sapiens (Human) EMBL AAH53321.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Hide | Top

Protein attributes

Sequence length380 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level.

Hide | Top

General annotation (Comments)

Sequence similarities

Contains 1 C2 domain.

Hide | Top

Ontologies

Keywords
   DomainRepeat Spearmint SPM002219
   LigandMetal-binding Spearmint SPM002219
Zinc Spearmint SPM002219
Gene Ontology (GO)
   Biological processintracellular signaling cascade

Inferred from electronic annotation. Source: InterPro

   Molecular functionzinc ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAH53321.1

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
Q7Z727-1 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: BDFBD8C8EC489604

FASTA38043,185
        10         20         30         40         50         60 
ASQRLRLPLP LRAAPARLSP APAAPPRRDL GHRPAPRARG RPEPAPLPRR PRPPGPPRPQ 

        70         80         90        100        110        120 
LPGGGKRWLG GTMADVFPGN DSTASQDVAN RFARKGALRQ KNVHEVKDHK FIARFFKQPT 

       130        140        150        160        170        180 
FCSHCTDFIW GFGKQGFQCQ VCCFVVHKRC HEFVTFSCPG ADKGPDTDDP RSKHKFKIHT 

       190        200        210        220        230        240 
YGSPTFCDHC GSLLYGLIHQ GMKCDTCDMN VHKQCVINVP SLCGMDHTEK RGRIYLKAEV 

       250        260        270        280        290        300 
ADEKLHVTVR DAKNLIPMDP NGLSDPYVKL KLIPDPKNES KQKTKTIRST LNPQWNESFT 

       310        320        330        340        350        360 
FKLKPSDKDR RLSVEIWDWD RTTRNDFMGS LSFGVSELMK MPASGWYKLL NQEEGEYYNV 

       370        380 
PIPEGDEEGN MELRQKFEWR

« Hide

Hide | Top

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Lung EMBL AAH53321.1.
+Additional computationally mapped references.

Hide | Top

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC053321 mRNA. Translation: AAH53321.1.
IPIIPI00748556.
RefSeqNP_002728.1.
UniGeneHs.531704
Hs.708867

3D structure databases

HSSPHSSP built from PDB template 1DSY based on UniProtKB P05696.
SMRQ7Z727. Positions 109-178, 165-241, 228-364.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ7Z727.

Genome annotation databases

GeneID5578.
KEGGhsa:5578.

Organism-specific databases

CTD5578.

Phylogenomic databases

HOVERGENQ7Z727.

Family and domain databases

InterProIPR000008. C2_Ca-dep.
IPR008973. C2_Ca/lipid-bd_dom_CaLB.
IPR018029. C2_membr_targeting.
IPR020477. C2_region.
IPR020454. DAG/PE_bd.
IPR002219. Prot_Kinase_C-like_PE/DAG_bd.
[Graphical view]
PfamPF00130. C1_1. 2 hits.
PF00168. C2. 1 hit.
[Graphical view]
PRINTSPR00360. C2DOMAIN.
PR00008. DAGPEDOMAIN.
SMARTSM00109. C1. 2 hits.
SM00239. C2. 1 hit.
[Graphical view]
PROSITEPS50004. C2. 1 hit.
PS00479. ZF_DAG_PE_1. 2 hits.
PS50081. ZF_DAG_PE_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio21628.

Hide | Top

Entry information

Entry nameQ7Z727_HUMAN
AccessionPrimary (citable) accession number: Q7Z727
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: February 9, 2010
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information