Q7Z5Y1 (Q7Z5Y1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Upstream stimulatory factor 1 Ensembl ENSP00000390109

Submitted name:
Upstream stimulatory factor 1 BD EMBL BAC78384.1

Gene names

Name:	usf1-bd EMBL BAC78384.1
Synonyms:	USF1 Ensembl ENSP00000390109

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAC78384.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	251 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 basic helix-loop-helix (bHLH) domain. RuleBase RU000367

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glucose metabolic process Inferred from electronic annotation. Source: Compara lipid homeostasis Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter by glucose Inferred from electronic annotation. Source: Compara response to UV Inferred from electronic annotation. Source: Compara
Cellular_component	nucleus Inferred from electronic annotation. Source: Compara
Molecular_function	double-stranded DNA binding Inferred from electronic annotation. Source: Compara sequence-specific DNA binding Inferred from electronic annotation. Source: Compara sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7Z5Y1 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: AA50D545E179EFCB	FASTA	251	27,372
	10 20 30 40 50 60 MYRVIQVSEG QLDGQTEGTG AISGYPATQS MTQAVIQGAF TSDDAVDTEG TAAETHYTYF 70 80 90 100 110 120 PSTAVGDGAG GTTSGSTAAV VTTQGSEALL GQATPPGTGQ FFVMMSPQEV LQGGSQRSIA 130 140 150 160 170 180 PRTHPYSPKS EAPRTTRDEK RRAQHNEVER RRRDKINNWI VQLSKIIPDC SMESTKSGQS 190 200 210 220 230 240 KGGILSKACD YIQELRQSNH RLSEELQGLD QLQLDNDVLR QQVEDLKNKN LLLRAQLRHH 250 GLEVVIKNDS N

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and characterization of a novel splicing isoform of USF1." Saito T., Oishi T., Yanai K., Shimamoto Y., Fukamizu A. Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., Porter K.M., Prigmore E. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL591806 Genomic DNA. No translation available. AB098540 mRNA. Translation: BAC78384.1.
IPI	IPI00413700.
RefSeq	NP_996888.1. NM_207005.2.
UniGene	Hs.414880.
3D structure databases
HSSP	HSSP built from PDB template 1AN4 based on UniProtKB P22415.
SMR	Q7Z5Y1. Positions 138-228.
ModBase	Search...
Protocols and materials databases
DNASU	7391.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000435396; ENSP00000390109; ENSG00000158773.
GeneID	7391.
KEGG	hsa:7391.
Organism-specific databases
CTD	7391.
HGNC	HGNC:12593. USF1.
PharmGKB	PA37223.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000294174.
HOVERGEN	HBG004346.
KO	K09106.
Gene expression databases
ArrayExpress	Q7Z5Y1.
Family and domain databases
Gene3D	4.10.280.10. 1 hit.
InterPro	IPR011598. bHLH_dom. [Graphical view]
Pfam	PF00010. HLH. 1 hit. [Graphical view]
SMART	SM00353. HLH. 1 hit. [Graphical view]
SUPFAM	SSF47459. HLH_basic. 1 hit.
PROSITE	PS50888. BHLH. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	USF1. human.
GenomeRNAi	7391.
NextBio	28938.

Entry information

Entry name

Q7Z5Y1_HUMAN

Accession

Primary (citable) accession number: Q7Z5Y1

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	October 1, 2003
Last modified:	May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.