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Q7Z5W8

- Q7Z5W8_HUMAN

UniProt

Q7Z5W8 - Q7Z5W8_HUMAN

Protein
Submitted name:

ACACA protein

Gene

ACACA

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (01 Oct 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. acetyl-CoA carboxylase activity Source: Ensembl

    GO - Biological processi

    1. acetyl-CoA metabolic process Source: Ensembl
    2. fatty acid biosynthetic process Source: Ensembl
    3. lipid homeostasis Source: Ensembl
    4. multicellular organismal protein metabolic process Source: Ensembl
    5. protein homotetramerization Source: Ensembl
    6. tissue homeostasis Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    ACACA proteinImported
    Gene namesi
    Name:ACACAImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: Ensembl
    2. mitochondrion Source: Ensembl

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA24421.

    PTM / Processingi

    Proteomic databases

    PRIDEiQ7Z5W8.

    Expressioni

    Gene expression databases

    ArrayExpressiQ7Z5W8.
    BgeeiQ7Z5W8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7Z5W8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000214115.
    HOVERGENiHBG086472.
    KOiK11262.

    Family and domain databases

    Gene3Di3.90.226.10. 3 hits.
    InterProiIPR000022. Carboxyl_trans.
    IPR029045. ClpP/crotonase-like_dom.
    IPR011763. COA_CT_C.
    IPR011762. COA_CT_N.
    [Graphical view]
    PfamiPF01039. Carboxyl_trans. 1 hit.
    [Graphical view]
    SUPFAMiSSF52096. SSF52096. 2 hits.
    PROSITEiPS50989. COA_CT_CTER. 1 hit.
    PS50980. COA_CT_NTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q7Z5W8-1 [UniParc]FASTAAdd to Basket

    « Hide

    IGMVAWKMTF KSPEYPEGRD IIVIGNDITY RIGSFGPQED LLFLRASELA    50
    RAEGIPRIYV SANSGARIGL AEEIRHMFHV AWVDPEDPYK GYRYLYLTPQ 100
    DYKRVSALNS VHCEHVEDEG ESRYKITDII GKEEGIGPEN LRGSGMIAGE 150
    SSLAYNEIIT ISLVTCRAIG IGAYLVRLGQ RTIQVENSHL ILTGAGALNK 200
    VLGREVYTSN NQLGGIQIMH NNGVTHCTVC DDFEGVFTVL HWLSYMPKSV 250
    HSSVPLLNSK DPIDRIIEFV PTKTPYDPRW MLAGRPHPTQ KGQWLSGFFD 300
    YGSFSEIMQP WAQTVVVGRA RLGGIPVGVV AVETRTVELS IPADPANLDS 350
    EAKIIQQAGQ VWFPDSAFKT YQAIKDFNRE GLPLMVFANW RGFSGGMKDM 400
    YDQVLKFGAY IVDGLRECCQ PVLVYIPPQA ELRGGSWVVI DSSINPRHME 450
    MYADRESRGS VLEPEGTVEI KFRRKDLVKT MRRVDPVYIH LAERLGTPEL 500
    STAERKELEN KLKEREEFLI PIYHQVAVQF ADLHDTPGRM QEKGVISDIL 550
    DWKTSRTFFY WRLRRLLLED LVKKKIHNAN PELTDGQIQA MLRRWFVEVE 600
    GTVKAYVWDN NKDLAEWLEK QLTEEDGVHS VIEENIKCIS RDYVLKQIRS 650
    LVQANPEVAM DSIIHMTQHI SPTQRAEVIR ILSTMDSPST 690
    Length:690
    Mass (Da):78,272
    Last modified:October 1, 2003 - v1
    Checksum:i54814516C7A58A06
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC031485 mRNA. Translation: AAH31485.1.
    RefSeqiNP_942134.1. NM_198837.1.
    NP_942135.1. NM_198838.1.
    UniGeneiHs.160556.

    Genome annotation databases

    GeneIDi31.
    KEGGihsa:31.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC031485 mRNA. Translation: AAH31485.1 .
    RefSeqi NP_942134.1. NM_198837.1.
    NP_942135.1. NM_198838.1.
    UniGenei Hs.160556.

    3D structure databases

    ProteinModelPortali Q7Z5W8.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q7Z5W8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 31.
    KEGGi hsa:31.

    Organism-specific databases

    CTDi 31.
    PharmGKBi PA24421.

    Phylogenomic databases

    HOGENOMi HOG000214115.
    HOVERGENi HBG086472.
    KOi K11262.

    Miscellaneous databases

    ChiTaRSi ACACA. human.
    GenomeRNAii 31.
    NextBioi 111.

    Gene expression databases

    ArrayExpressi Q7Z5W8.
    Bgeei Q7Z5W8.

    Family and domain databases

    Gene3Di 3.90.226.10. 3 hits.
    InterProi IPR000022. Carboxyl_trans.
    IPR029045. ClpP/crotonase-like_dom.
    IPR011763. COA_CT_C.
    IPR011762. COA_CT_N.
    [Graphical view ]
    Pfami PF01039. Carboxyl_trans. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52096. SSF52096. 2 hits.
    PROSITEi PS50989. COA_CT_CTER. 1 hit.
    PS50980. COA_CT_NTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: EyeImported.

    Entry informationi

    Entry nameiQ7Z5W8_HUMAN
    AccessioniPrimary (citable) accession number: Q7Z5W8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2003
    Last sequence update: October 1, 2003
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.