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Q7Z5W8

- Q7Z5W8_HUMAN

UniProt

Q7Z5W8 - Q7Z5W8_HUMAN

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Protein
Submitted name: ACACA protein
Gene
ACACA
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. acetyl-CoA carboxylase activity Source: Ensembl

GO - Biological processi

  1. acetyl-CoA metabolic process Source: Ensembl
  2. fatty acid biosynthetic process Source: Ensembl
  3. lipid homeostasis Source: Ensembl
  4. multicellular organismal protein metabolic process Source: Ensembl
  5. protein homotetramerization Source: Ensembl
  6. tissue homeostasis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ACACA proteinImported
Gene namesi
Name:ACACAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. mitochondrion Source: Ensembl
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24421.

PTM / Processingi

Proteomic databases

PRIDEiQ7Z5W8.

Expressioni

Gene expression databases

ArrayExpressiQ7Z5W8.
BgeeiQ7Z5W8.

Structurei

3D structure databases

ProteinModelPortaliQ7Z5W8.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000214115.
HOVERGENiHBG086472.
KOiK11262.

Family and domain databases

Gene3Di3.90.226.10. 3 hits.
InterProiIPR000022. Carboxyl_trans.
IPR029045. ClpP/crotonase-like_dom.
IPR011763. COA_CT_C.
IPR011762. COA_CT_N.
[Graphical view]
PfamiPF01039. Carboxyl_trans. 1 hit.
[Graphical view]
SUPFAMiSSF52096. SSF52096. 2 hits.
PROSITEiPS50989. COA_CT_CTER. 1 hit.
PS50980. COA_CT_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q7Z5W8-1 [UniParc]FASTAAdd to Basket

« Hide

IGMVAWKMTF KSPEYPEGRD IIVIGNDITY RIGSFGPQED LLFLRASELA    50
RAEGIPRIYV SANSGARIGL AEEIRHMFHV AWVDPEDPYK GYRYLYLTPQ 100
DYKRVSALNS VHCEHVEDEG ESRYKITDII GKEEGIGPEN LRGSGMIAGE 150
SSLAYNEIIT ISLVTCRAIG IGAYLVRLGQ RTIQVENSHL ILTGAGALNK 200
VLGREVYTSN NQLGGIQIMH NNGVTHCTVC DDFEGVFTVL HWLSYMPKSV 250
HSSVPLLNSK DPIDRIIEFV PTKTPYDPRW MLAGRPHPTQ KGQWLSGFFD 300
YGSFSEIMQP WAQTVVVGRA RLGGIPVGVV AVETRTVELS IPADPANLDS 350
EAKIIQQAGQ VWFPDSAFKT YQAIKDFNRE GLPLMVFANW RGFSGGMKDM 400
YDQVLKFGAY IVDGLRECCQ PVLVYIPPQA ELRGGSWVVI DSSINPRHME 450
MYADRESRGS VLEPEGTVEI KFRRKDLVKT MRRVDPVYIH LAERLGTPEL 500
STAERKELEN KLKEREEFLI PIYHQVAVQF ADLHDTPGRM QEKGVISDIL 550
DWKTSRTFFY WRLRRLLLED LVKKKIHNAN PELTDGQIQA MLRRWFVEVE 600
GTVKAYVWDN NKDLAEWLEK QLTEEDGVHS VIEENIKCIS RDYVLKQIRS 650
LVQANPEVAM DSIIHMTQHI SPTQRAEVIR ILSTMDSPST 690
Length:690
Mass (Da):78,272
Last modified:October 1, 2003 - v1
Checksum:i54814516C7A58A06
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC031485 mRNA. Translation: AAH31485.1.
RefSeqiNP_942134.1. NM_198837.1.
NP_942135.1. NM_198838.1.
UniGeneiHs.160556.

Genome annotation databases

GeneIDi31.
KEGGihsa:31.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC031485 mRNA. Translation: AAH31485.1 .
RefSeqi NP_942134.1. NM_198837.1.
NP_942135.1. NM_198838.1.
UniGenei Hs.160556.

3D structure databases

ProteinModelPortali Q7Z5W8.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q7Z5W8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 31.
KEGGi hsa:31.

Organism-specific databases

CTDi 31.
PharmGKBi PA24421.

Phylogenomic databases

HOGENOMi HOG000214115.
HOVERGENi HBG086472.
KOi K11262.

Miscellaneous databases

ChiTaRSi ACACA. human.
GenomeRNAii 31.
NextBioi 111.

Gene expression databases

ArrayExpressi Q7Z5W8.
Bgeei Q7Z5W8.

Family and domain databases

Gene3Di 3.90.226.10. 3 hits.
InterProi IPR000022. Carboxyl_trans.
IPR029045. ClpP/crotonase-like_dom.
IPR011763. COA_CT_C.
IPR011762. COA_CT_N.
[Graphical view ]
Pfami PF01039. Carboxyl_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF52096. SSF52096. 2 hits.
PROSITEi PS50989. COA_CT_CTER. 1 hit.
PS50980. COA_CT_NTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EyeImported.

Entry informationi

Entry nameiQ7Z5W8_HUMAN
AccessioniPrimary (citable) accession number: Q7Z5W8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: July 9, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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