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Protein

NANOG neighbor homeobox

Gene

NANOGNB

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi102 – 161HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
NANOG neighbor homeobox
Alternative name(s):
Homeobox protein C14
Gene namesi
Name:NANOGNB
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000205857.1.
HGNCiHGNC:24958. NANOGNB.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA165513123.

Polymorphism and mutation databases

BioMutaiNANOGNB.
DMDMi74759191.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003414171 – 188NANOG neighbor homeoboxAdd BLAST188

Proteomic databases

PaxDbiQ7Z5D8.
PeptideAtlasiQ7Z5D8.
PRIDEiQ7Z5D8.

PTM databases

iPTMnetiQ7Z5D8.
PhosphoSitePlusiQ7Z5D8.

Expressioni

Gene expression databases

BgeeiENSG00000205857.

Organism-specific databases

HPAiHPA060371.

Interactioni

Protein-protein interaction databases

BioGridi131826. 1 interactor.
STRINGi9606.ENSP00000371553.

Structurei

3D structure databases

ProteinModelPortaliQ7Z5D8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiENOG410JG80. Eukaryota.
ENOG4111BTG. LUCA.
GeneTreeiENSGT00400000025247.
InParanoidiQ7Z5D8.
OMAiLMDTLWA.
OrthoDBiEOG091G16VB.
PhylomeDBiQ7Z5D8.
TreeFamiTF350480.

Family and domain databases

InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR001356. Homeobox_dom.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7Z5D8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHRARWLTPV IPALWEAEAG RSRGQEIETI LANKKQSAMP WDQDPEQSTG
60 70 80 90 100
NYSEDEQNGK QKWREEGEAG RKREREKEEK NEKELQDEQE NKRKRENEKQ
110 120 130 140 150
KQYPEKRLVS KSLMHTLWAK FKLNRCPTIQ ESLSLSFEFD MTHKQISQWF
160 170 180
CKTRKKYNKE MSKRKHKKKH MRWRSLCCQG WSRTPALK
Length:188
Mass (Da):22,750
Last modified:October 1, 2003 - v1
Checksum:i8C907E0B232146F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY151139 mRNA. Translation: AAP76323.1.
BC036226 mRNA. No translation available.
CCDSiCCDS44826.1.
RefSeqiNP_001138937.1. NM_001145465.1.
UniGeneiHs.558004.

Genome annotation databases

EnsembliENST00000382119; ENSP00000371553; ENSG00000205857.
GeneIDi360030.
KEGGihsa:360030.
UCSCiuc009zfx.2. human.

Similar proteinsi

Entry informationi

Entry nameiNANGN_HUMAN
AccessioniPrimary (citable) accession number: Q7Z5D8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: October 1, 2003
Last modified: September 27, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM