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Protein

NANOG neighbor homeobox

Gene

NANOGNB

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi102 – 161HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
NANOG neighbor homeobox
Alternative name(s):
Homeobox protein C14
Gene namesi
Name:NANOGNB
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:24958. NANOGNB.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000205857.
PharmGKBiPA165513123.

Polymorphism and mutation databases

BioMutaiNANOGNB.
DMDMi74759191.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003414171 – 188NANOG neighbor homeoboxAdd BLAST188

Proteomic databases

PaxDbiQ7Z5D8.
PeptideAtlasiQ7Z5D8.
PRIDEiQ7Z5D8.

PTM databases

iPTMnetiQ7Z5D8.
PhosphoSitePlusiQ7Z5D8.

Expressioni

Gene expression databases

BgeeiENSG00000205857.

Organism-specific databases

HPAiHPA060371.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi131826. 1 interactor.
STRINGi9606.ENSP00000371553.

Structurei

3D structure databases

ProteinModelPortaliQ7Z5D8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiENOG410JG80. Eukaryota.
ENOG4111BTG. LUCA.
GeneTreeiENSGT00400000025247.
InParanoidiQ7Z5D8.
OMAiKQISQWF.
OrthoDBiEOG091G16VB.
PhylomeDBiQ7Z5D8.
TreeFamiTF350480.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7Z5D8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHRARWLTPV IPALWEAEAG RSRGQEIETI LANKKQSAMP WDQDPEQSTG
60 70 80 90 100
NYSEDEQNGK QKWREEGEAG RKREREKEEK NEKELQDEQE NKRKRENEKQ
110 120 130 140 150
KQYPEKRLVS KSLMHTLWAK FKLNRCPTIQ ESLSLSFEFD MTHKQISQWF
160 170 180
CKTRKKYNKE MSKRKHKKKH MRWRSLCCQG WSRTPALK
Length:188
Mass (Da):22,750
Last modified:October 1, 2003 - v1
Checksum:i8C907E0B232146F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY151139 mRNA. Translation: AAP76323.1.
BC036226 mRNA. No translation available.
CCDSiCCDS44826.1.
RefSeqiNP_001138937.1. NM_001145465.1.
UniGeneiHs.558004.

Genome annotation databases

EnsembliENST00000382119; ENSP00000371553; ENSG00000205857.
GeneIDi360030.
KEGGihsa:360030.
UCSCiuc009zfx.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY151139 mRNA. Translation: AAP76323.1.
BC036226 mRNA. No translation available.
CCDSiCCDS44826.1.
RefSeqiNP_001138937.1. NM_001145465.1.
UniGeneiHs.558004.

3D structure databases

ProteinModelPortaliQ7Z5D8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi131826. 1 interactor.
STRINGi9606.ENSP00000371553.

PTM databases

iPTMnetiQ7Z5D8.
PhosphoSitePlusiQ7Z5D8.

Polymorphism and mutation databases

BioMutaiNANOGNB.
DMDMi74759191.

Proteomic databases

PaxDbiQ7Z5D8.
PeptideAtlasiQ7Z5D8.
PRIDEiQ7Z5D8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000382119; ENSP00000371553; ENSG00000205857.
GeneIDi360030.
KEGGihsa:360030.
UCSCiuc009zfx.2. human.

Organism-specific databases

CTDi360030.
GeneCardsiNANOGNB.
HGNCiHGNC:24958. NANOGNB.
HPAiHPA060371.
neXtProtiNX_Q7Z5D8.
OpenTargetsiENSG00000205857.
PharmGKBiPA165513123.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410JG80. Eukaryota.
ENOG4111BTG. LUCA.
GeneTreeiENSGT00400000025247.
InParanoidiQ7Z5D8.
OMAiKQISQWF.
OrthoDBiEOG091G16VB.
PhylomeDBiQ7Z5D8.
TreeFamiTF350480.

Miscellaneous databases

ChiTaRSiNANOGNB. human.
GenomeRNAii360030.
PROiQ7Z5D8.

Gene expression databases

BgeeiENSG00000205857.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNANGN_HUMAN
AccessioniPrimary (citable) accession number: Q7Z5D8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: October 1, 2003
Last modified: November 2, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.