Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q7Z5A9

- F19A1_HUMAN

UniProt

Q7Z5A9 - F19A1_HUMAN

Protein

Protein FAM19A1

Gene

FAM19A1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein FAM19A1
    Alternative name(s):
    Chemokine-like protein TAFA-1
    Gene namesi
    Name:FAM19A1
    Synonyms:TAFA1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 3

    Organism-specific databases

    HGNCiHGNC:21587. FAM19A1.

    Subcellular locationi

    Secreted 1 Publication

    GO - Cellular componenti

    1. endoplasmic reticulum Source: LIFEdb
    2. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134907870.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919Sequence AnalysisAdd
    BLAST
    Chaini20 – 133114Protein FAM19A1PRO_0000042721Add
    BLAST

    Proteomic databases

    PaxDbiQ7Z5A9.
    PRIDEiQ7Z5A9.

    PTM databases

    PhosphoSiteiQ7Z5A9.

    Expressioni

    Tissue specificityi

    Brain-specific.1 Publication

    Gene expression databases

    BgeeiQ7Z5A9.
    CleanExiHS_FAM19A1.
    GenevestigatoriQ7Z5A9.

    Organism-specific databases

    HPAiHPA013407.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-4722638.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7Z5A9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the FAM19/TAFA family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG42910.
    HOGENOMiHOG000236302.
    HOVERGENiHBG081496.
    InParanoidiQ7Z5A9.
    OMAiGWMCYAG.
    OrthoDBiEOG7JDR0R.
    PhylomeDBiQ7Z5A9.
    TreeFamiTF331749.

    Family and domain databases

    InterProiIPR020350. Chemokine-like_FAM19A2.
    [Graphical view]
    PfamiPF12020. TAFA. 1 hit.
    [Graphical view]
    ProDomiPD298472. Chemokine-like_2FAM19A2. 1 hit.
    [Graphical view] [Entries sharing at least one domain]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q7Z5A9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAMVSAMSWV LYLWISACAM LLCHGSLQHT FQQHHLHRPE GGTCEVIAAH    50
    RCCNKNRIEE RSQTVKCSCL PGKVAGTTRN RPSCVDASIV IGKWWCEMEP 100
    CLEGEECKTL PDNSGWMCAT GNKIKTTRIH PRT 133
    Length:133
    Mass (Da):14,901
    Last modified:October 1, 2003 - v1
    Checksum:iC5DD1C7E5F997386
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti92 – 921G → W in CAD28501. (PubMed:17974005)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY325114 mRNA. Translation: AAP92406.1.
    AK289668 mRNA. Translation: BAF82357.1.
    AK290446 mRNA. Translation: BAF83135.1.
    AL713702 mRNA. Translation: CAD28501.1.
    BC025746 mRNA. Translation: AAH25746.1.
    CCDSiCCDS54606.1.
    RefSeqiNP_001239145.1. NM_001252216.1.
    NP_998774.2. NM_213609.3.
    UniGeneiHs.655061.
    Hs.731727.

    Genome annotation databases

    EnsembliENST00000478136; ENSP00000418575; ENSG00000183662.
    ENST00000496687; ENSP00000417496; ENSG00000183662.
    GeneIDi407738.
    KEGGihsa:407738.
    UCSCiuc003dnd.3. human.

    Polymorphism databases

    DMDMi74738719.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY325114 mRNA. Translation: AAP92406.1 .
    AK289668 mRNA. Translation: BAF82357.1 .
    AK290446 mRNA. Translation: BAF83135.1 .
    AL713702 mRNA. Translation: CAD28501.1 .
    BC025746 mRNA. Translation: AAH25746.1 .
    CCDSi CCDS54606.1.
    RefSeqi NP_001239145.1. NM_001252216.1.
    NP_998774.2. NM_213609.3.
    UniGenei Hs.655061.
    Hs.731727.

    3D structure databases

    ProteinModelPortali Q7Z5A9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-4722638.

    PTM databases

    PhosphoSitei Q7Z5A9.

    Polymorphism databases

    DMDMi 74738719.

    Proteomic databases

    PaxDbi Q7Z5A9.
    PRIDEi Q7Z5A9.

    Protocols and materials databases

    DNASUi 407738.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000478136 ; ENSP00000418575 ; ENSG00000183662 .
    ENST00000496687 ; ENSP00000417496 ; ENSG00000183662 .
    GeneIDi 407738.
    KEGGi hsa:407738.
    UCSCi uc003dnd.3. human.

    Organism-specific databases

    CTDi 407738.
    GeneCardsi GC03P068139.
    HGNCi HGNC:21587. FAM19A1.
    HPAi HPA013407.
    neXtProti NX_Q7Z5A9.
    PharmGKBi PA134907870.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG42910.
    HOGENOMi HOG000236302.
    HOVERGENi HBG081496.
    InParanoidi Q7Z5A9.
    OMAi GWMCYAG.
    OrthoDBi EOG7JDR0R.
    PhylomeDBi Q7Z5A9.
    TreeFami TF331749.

    Miscellaneous databases

    ChiTaRSi FAM19A1. human.
    GenomeRNAii 407738.
    NextBioi 108332.
    PROi Q7Z5A9.

    Gene expression databases

    Bgeei Q7Z5A9.
    CleanExi HS_FAM19A1.
    Genevestigatori Q7Z5A9.

    Family and domain databases

    InterProi IPR020350. Chemokine-like_FAM19A2.
    [Graphical view ]
    Pfami PF12020. TAFA. 1 hit.
    [Graphical view ]
    ProDomi PD298472. Chemokine-like_2FAM19A2. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    ProtoNeti Search...

    Publicationsi

    1. "TAFA: a novel secreted family with conserved cysteine residues and restricted expression in the brain."
      Tom Tang Y., Emtage P., Funk W.D., Hu T., Arterburn M., Park E.E., Rupp F.
      Genomics 83:727-734(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, SUBCELLULAR LOCATION.
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Amygdala and Brain.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Kidney.
    4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Brain.

    Entry informationi

    Entry nameiF19A1_HUMAN
    AccessioniPrimary (citable) accession number: Q7Z5A9
    Secondary accession number(s): A8K0V3, Q8TCL8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2005
    Last sequence update: October 1, 2003
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 3
      Human chromosome 3: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3