Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein FAM19A1

Gene

FAM19A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM19A1
Alternative name(s):
Chemokine-like protein TAFA-1
Gene namesi
Name:FAM19A1
Synonyms:TAFA1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000183662.10
HGNCiHGNC:21587 FAM19A1
MIMi617495 gene
neXtProtiNX_Q7Z5A9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

DisGeNETi407738
OpenTargetsiENSG00000183662
PharmGKBiPA134907870

Polymorphism and mutation databases

BioMutaiFAM19A1
DMDMi74738719

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000004272120 – 133Protein FAM19A1Add BLAST114

Proteomic databases

PaxDbiQ7Z5A9
PeptideAtlasiQ7Z5A9
PRIDEiQ7Z5A9

PTM databases

iPTMnetiQ7Z5A9
PhosphoSitePlusiQ7Z5A9

Expressioni

Tissue specificityi

Brain-specific.1 Publication

Gene expression databases

BgeeiENSG00000183662
CleanExiHS_FAM19A1
ExpressionAtlasiQ7Z5A9 baseline and differential
GenevisibleiQ7Z5A9 HS

Organism-specific databases

HPAiHPA013407

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
RABGGTBP536113EBI-10257895,EBI-536715

Protein-protein interaction databases

BioGridi135906, 4 interactors
IntActiQ7Z5A9, 1 interactor
STRINGi9606.ENSP00000417496

Structurei

3D structure databases

ProteinModelPortaliQ7Z5A9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM19/TAFA family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IWJ7 Eukaryota
ENOG410YH4T LUCA
GeneTreeiENSGT00390000001768
HOGENOMiHOG000236302
HOVERGENiHBG081496
InParanoidiQ7Z5A9
OMAiGWMCYAG
OrthoDBiEOG091G0TKK
PhylomeDBiQ7Z5A9
TreeFamiTF331749

Family and domain databases

InterProiView protein in InterPro
IPR020350 Chemokine-like_FAM19A2
PfamiView protein in Pfam
PF12020 TAFA, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD298472 Chemokine-like_2FAM19A2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q7Z5A9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMVSAMSWV LYLWISACAM LLCHGSLQHT FQQHHLHRPE GGTCEVIAAH
60 70 80 90 100
RCCNKNRIEE RSQTVKCSCL PGKVAGTTRN RPSCVDASIV IGKWWCEMEP
110 120 130
CLEGEECKTL PDNSGWMCAT GNKIKTTRIH PRT
Length:133
Mass (Da):14,901
Last modified:October 1, 2003 - v1
Checksum:iC5DD1C7E5F997386
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti92G → W in CAD28501 (PubMed:17974005).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY325114 mRNA Translation: AAP92406.1
AK289668 mRNA Translation: BAF82357.1
AK290446 mRNA Translation: BAF83135.1
AL713702 mRNA Translation: CAD28501.1
BC025746 mRNA Translation: AAH25746.1
CCDSiCCDS54606.1
RefSeqiNP_001239145.1, NM_001252216.1
NP_998774.2, NM_213609.3
XP_016861875.1, XM_017006386.1
XP_016861876.1, XM_017006387.1
UniGeneiHs.655061
Hs.731727

Genome annotation databases

EnsembliENST00000478136; ENSP00000418575; ENSG00000183662
ENST00000496687; ENSP00000417496; ENSG00000183662
GeneIDi407738
KEGGihsa:407738
UCSCiuc003dne.4 human

Similar proteinsi

Entry informationi

Entry nameiF19A1_HUMAN
AccessioniPrimary (citable) accession number: Q7Z5A9
Secondary accession number(s): A8K0V3, Q8TCL8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: October 1, 2003
Last modified: March 28, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health