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Q7Z591 (AKNA_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
AT-hook-containing transcription factor
Gene names
Name:AKNA
Synonyms:KIAA1968
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1439 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Transcription factor that specifically activates the expression of the CD40 receptor and its ligand CD40L/CD154, two cell surface molecules on lymphocytes that are critical for antigen-dependent-B-cell development. Binds to A/T-rich promoters. Ref.6

Subcellular location

Nucleus Ref.6.

Tissue specificity

Predominantly expressed by lymphoid tissues. Highly expressed in the spleen, lymph nodes and peripheral blood leukocytes, expressed at lower level in the thymus. Mainly expressed by germinal center B-lymphocytes, a stage in which receptor and ligand interactions are crucial for B-lymphocyte maturation. Expressed by B- and T-lymphocytes, Natural killer cells and CD1a+CD14- but not CD1a-CD14+ dendritic cells. Weakly or not expressed in fetal liver and in adult bone marrow. Ref.6

Sequence similarities

Contains 1 A.T hook DNA-binding domain.

Sequence caution

The sequence AAK83024.1 differs from that shown. Reason: Frameshift at position 1228.

The sequence AAU34192.1 differs from that shown. Reason: Frameshift at position 1227.

The sequence BAB84866.1 differs from that shown. Reason: Erroneous initiation.

The sequence BAB85554.1 differs from that shown. Reason: Erroneous initiation.

The sequence BAC85132.1 differs from that shown. Reason: Frameshift at position 1340.

The sequence BAD18725.1 differs from that shown. Reason: Frameshift at positions 820, 1017, 1340, 1387 and 1434.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   Coding sequence diversityAlternative splicing
Polymorphism
   LigandDNA-binding
   Molecular functionActivator
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processregulation of transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Alternative products

This entry describes 8 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q7Z591-1)

Also known as: B2; D;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q7Z591-2)

Also known as: E;

The sequence of this isoform differs from the canonical sequence as follows:
     1-91: MASSETEIRW...DSESGETSGE → MLRSEWPVFP
Isoform 3 (identifier: Q7Z591-3)

The sequence of this isoform differs from the canonical sequence as follows:
     832-1439: Missing.
Isoform 4 (identifier: Q7Z591-4)

The sequence of this isoform differs from the canonical sequence as follows:
     1-1055: Missing.
     1056-1074: PCGPTETIPSFLLTRAGRD → MSAGGGTRGYSPRSPGATS
Note: No experimental confirmation available.
Isoform 5 (identifier: Q7Z591-5)

Also known as: F1;

The sequence of this isoform differs from the canonical sequence as follows:
     1-753: Missing.
Isoform 6 (identifier: Q7Z591-6)

The sequence of this isoform differs from the canonical sequence as follows:
     448-572: EDYHRLLTKY...TQALASQASQ → VSGTHGCGCV...GGWLGQEALG
     573-1439: Missing.
Isoform 7 (identifier: Q7Z591-7)

Also known as: A;

The sequence of this isoform differs from the canonical sequence as follows:
     1-119: Missing.
Isoform 8 (identifier: Q7Z591-8)

The sequence of this isoform differs from the canonical sequence as follows:
     1-540: Missing.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 14391439AT-hook-containing transcription factor
PRO_0000289159

Regions

DNA binding1115 – 11239A.T hook Ref.6
Region771 – 80434PEST
Region911 – 93222PEST

Amino acid modifications

Modified residue5341Phosphoserine Ref.7
Modified residue13871Phosphoserine Ref.7

Natural variations

Alternative sequence1 – 10551055Missing in isoform 4.
VSP_025932
Alternative sequence1 – 753753Missing in isoform 5.
VSP_025933
Alternative sequence1 – 540540Missing in isoform 8.
VSP_025934
Alternative sequence1 – 119119Missing in isoform 7.
VSP_025935
Alternative sequence1 – 9191MASSE…ETSGE → MLRSEWPVFP in isoform 2.
VSP_025936
Alternative sequence448 – 572125EDYHR…SQASQ → VSGTHGCGCVTKAPVGLGWR LIGVGRPGVEAGWGGEAWDR AWLGWEALGRRLVGWGGLGW RLARVGSPGMEASGVGRPGV GSPGVEPGGVGRPGVEAGWG RKPWDRGWWGGEAWGGGWLG QEALG in isoform 6.
VSP_025937
Alternative sequence573 – 1439867Missing in isoform 6.
VSP_025938
Alternative sequence832 – 1439608Missing in isoform 3.
VSP_025939
Alternative sequence1056 – 107419PCGPT…RAGRD → MSAGGGTRGYSPRSPGATS in isoform 4.
VSP_025940
Natural variant6241P → L. Ref.2 Ref.3
Corresponds to variant rs3748176 [ dbSNP | Ensembl ].
VAR_032586
Natural variant10971Q → R.
Corresponds to variant rs1265891 [ dbSNP | Ensembl ].
VAR_032587
Natural variant11191R → Q. Ref.3
Corresponds to variant rs3748178 [ dbSNP | Ensembl ].
VAR_032588
Natural variant13031S → P. Ref.3 Ref.5
Corresponds to variant rs2250242 [ dbSNP | Ensembl ].
VAR_032589
Natural variant13271Y → C.
Corresponds to variant rs2787344 [ dbSNP | Ensembl ].
VAR_032590

Experimental info

Sequence conflict7991D → V in BAD18725. Ref.3
Sequence conflict7991D → V in BAC85132. Ref.3
Sequence conflict8161R → S in BAD18725. Ref.3
Sequence conflict10371L → F in AAK83024. Ref.6
Sequence conflict11031P → Q in BAD18725. Ref.3
Sequence conflict11141A → P in BAD18725. Ref.3
Sequence conflict14291Q → P in BAD18725. Ref.3
Sequence conflict1435 – 14362GS → AP in BAD18725. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 (B2) (D) [UniParc].

Last modified May 29, 2007. Version 2.
Checksum: 51688A0C5C55A7BE

FASTA1,439155,139
        10         20         30         40         50         60 
MASSETEIRW AEPGLGKGPQ RRRWAWAEDK RDVDRSSSQS WEEERLFPNA TSPELLEDFR 

        70         80         90        100        110        120 
LAQQHLPPLE WDPHPQPDGH QDSESGETSG EEAEAEDVDS PASSHEPLAW LPQQGRQLDM 

       130        140        150        160        170        180 
TEEEPDGTLG SLEVEEAGES SSRLGYEAGL SLEGHGNTSP MALGHGQARG WVASGEQASG 

       190        200        210        220        230        240 
DKLSEHSEVN PSVELSPARS WSSGTVSLDH PSDSLDSTWE GETDGPQPTA LAETLPEGPS 

       250        260        270        280        290        300 
HHLLSPDGRT GGSVARATPM EFQDSSAPPA QSPQHATDRW RRETTRFFCP QPKEHIWKQT 

       310        320        330        340        350        360 
KTSPKPLPSR FIGSISPLNP QPRPTRQGRP LPRQGATLAG RSSSNAPKYG RGQLNYPLPD 

       370        380        390        400        410        420 
FSKVGPRVRF PKDESYRPPK SRSHNRKPQA PARPLIFKSP AEIVQEVLLS SGEAALAKDT 

       430        440        450        460        470        480 
PPAHPITRVP QEFQTPEQAT ELVHQLQEDY HRLLTKYAEA ENTIDQLRLG AKVNLFSDPP 

       490        500        510        520        530        540 
QPNHSIHTGM VPQGTKVLSF TIPQPRSAEW WPGPAEDPQA SAASGWPSAR GDLSPSSLTS 

       550        560        570        580        590        600 
MPTLGWLPEN RDISEDQSSA EQTQALASQA SQFLAKVESF ERLIQAGRLM PQDQVKGFQR 

       610        620        630        640        650        660 
LKAAHAALEE EYLKACREQH PAQPLAGSKG TPGRFDPRRE LEAEIYRLGS CLEELKEHID 

       670        680        690        700        710        720 
QTQQEPEPPG SDSALDSTPA LPCLHQPTHL PAPSGQAPMP AIKTSCPEPA TTTAAASTGP 

       730        740        750        760        770        780 
CPLHVNVEVS SGNSEVEDRP QDPLARLRHK ELQMEQVYHG LMERYLSVKS LPEAMRMEEE 

       790        800        810        820        830        840 
EEGEEEEEEE GGGDSLEVDG VAATPGKAEA TRVLPRQCPV QAEKSHGAPL EEATEKMVSM 

       850        860        870        880        890        900 
KPPGFQASLA RDGHMSGLGK AEAAPPGPGV PPHPPGTKSA ASHQSSMTSL EGSGISERLP 

       910        920        930        940        950        960 
QKPLHRGGGP HLEETWMASP ETDSGFVGSE TSRVSPLTQT PEHRLSHIST AGTLAQPFAA 

       970        980        990       1000       1010       1020 
SVPRDGASYP KARGSLIPRR ATEPSTPRSQ AQRYLSSPSG PLRQRAPNFS LERTLAAEMA 

      1030       1040       1050       1060       1070       1080 
VPGSEFEGHK RISEQPLPNK TISPPPAPAP AAAPLPCGPT ETIPSFLLTR AGRDQAICEL 

      1090       1100       1110       1120       1130       1140 
QEEVSRLRLR LEDSLHQPLQ GSPTRPASAF DRPARTRGRP ADSPATWGSH YGSKSTERLP 

      1150       1160       1170       1180       1190       1200 
GEPRGEEQIV PPGRQRARSS SVPREVLRLS LSSESELPSL PLFSEKSKTT KDSPQAARDG 

      1210       1220       1230       1240       1250       1260 
KRGVGSAGWP DRVTFRGQYT GHEYHVLSPK AVPKGNGTVS CPHCRPIRTQ DAGGAVTGDP 

      1270       1280       1290       1300       1310       1320 
LGPPPADTLQ CPLCGQVGSP PEADGPGSAT SGAEKATTRR KASSTPSPKQ RSKQAGSSPR 

      1330       1340       1350       1360       1370       1380 
PPPGLWYLAT APPAPAPPAF AYISSVPIMP YPPAAVYYAP AGPTSAQPAA KWPPTASPPP 

      1390       1400       1410       1420       1430 
ARRHRHSIQL DLGDLEELNK ALSRAVQAAE SVRSTTRQMR SSLSADLRQA HSLRGSCLF 

« Hide

Isoform 2 (E) [UniParc].

Checksum: A96C7EBC4EF10401
Show »

FASTA1,358145,921
Isoform 3 [UniParc].

Checksum: 60F24D16072CF37D
Show »

FASTA83190,917
Isoform 4 [UniParc].

Checksum: D195D6878CCF4F5C
Show »

FASTA38440,606
Isoform 5 (F1) [UniParc].

Checksum: 77843A242C71E4E2
Show »

FASTA68672,810
Isoform 6 [UniParc].

Checksum: C5AA7024B767C695
Show »

FASTA57261,839
Isoform 7 (A) [UniParc].

Checksum: BB6B6B38C6C0AFB0
Show »

FASTA1,320141,619
Isoform 8 [UniParc].

Checksum: CB0341DD1715B61F
Show »

FASTA89996,014

References

« Hide 'large scale' references
[1]"The human AKNA gene expresses multiple transcripts and protein isoforms as a result of alternative promoter usage, splicing, and polyadenylation."
Sims-Mourtada J.C., Bruce S., McKeller M.R., Rangel R., Guzman-Rojas L., Cain K., Lopez C., Zimonjic D.B., Popescu N.C., Gordon J., Wilkinson M.F., Martinez-Valdez H.
DNA Cell Biol. 24:325-338(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 5; 6 AND 7).
[2]"Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins."
Nagase T., Kikuno R., Ohara O.
DNA Res. 8:319-327(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), VARIANT LEU-624.
Tissue: Brain.
[3]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 8), VARIANTS LEU-624; GLN-1119 AND PRO-1303.
Tissue: Spleen.
[4]"DNA sequence and analysis of human chromosome 9."
Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. expand/collapse author list , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 4), VARIANT PRO-1303.
Tissue: Eye.
[6]"Regulation of CD40 and CD40 ligand by the AT-hook transcription factor AKNA."
Siddiqa A., Sims-Mourtada J.C., Guzman-Rojas L., Rangel R., Guret C., Madrid-Marina V., Sun Y., Martinez-Valdez H.
Nature 410:383-387(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 762-1395, FUNCTION, SUBCELLULAR LOCATION, DNA-BINDING, TISSUE SPECIFICITY.
[7]"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-534 AND SER-1387, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Leukemic T-cell.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY703039 mRNA. Translation: AAU34186.1.
AY703043 mRNA. Translation: AAU34190.1.
AY703044 mRNA. Translation: AAU34191.1.
AY703045 mRNA. Translation: AAU34192.1. Frameshift.
AB075848 mRNA. Translation: BAB85554.1. Different initiation.
AK024431 mRNA. Translation: BAB15721.1.
AK074040 mRNA. Translation: BAB84866.1. Different initiation.
AK131082 mRNA. Translation: BAC85132.1. Sequence problems.
AK160382 mRNA. Translation: BAD18725.1. Sequence problems.
AL356796 Genomic DNA. Translation: CAM23638.1.
AL356796 Genomic DNA. Translation: CAI16861.1.
AL356796 Genomic DNA. Translation: CAI16862.2.
AL356796 Genomic DNA. Translation: CAI16863.1.
BC042202 mRNA. Translation: AAH42202.1.
BC055285 mRNA. Translation: AAH55285.1.
AF286341 mRNA. Translation: AAK83024.1. Frameshift.
RefSeqNP_110394.3. NM_030767.4.
XP_005252300.1. XM_005252243.1.
XP_005252301.1. XM_005252244.1.
XP_005252302.1. XM_005252245.1.
XP_005252303.1. XM_005252246.2.
XP_005252304.1. XM_005252247.2.
UniGeneHs.494895.

3D structure databases

ProteinModelPortalQ7Z591.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid123268. 2 interactions.
IntActQ7Z591. 2 interactions.
MINTMINT-1366492.

PTM databases

PhosphoSiteQ7Z591.

Polymorphism databases

DMDM150416853.

Proteomic databases

PaxDbQ7Z591.
PRIDEQ7Z591.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000223791; ENSP00000223791; ENSG00000106948. [Q7Z591-8]
ENST00000307564; ENSP00000303769; ENSG00000106948. [Q7Z591-1]
ENST00000312033; ENSP00000309222; ENSG00000106948. [Q7Z591-3]
ENST00000374075; ENSP00000363188; ENSG00000106948. [Q7Z591-2]
ENST00000374079; ENSP00000363192; ENSG00000106948. [Q7Z591-4]
ENST00000374088; ENSP00000363201; ENSG00000106948. [Q7Z591-1]
GeneID80709.
KEGGhsa:80709.
UCSCuc004bin.3. human. [Q7Z591-5]
uc004bio.3. human. [Q7Z591-1]
uc004bip.3. human. [Q7Z591-2]
uc004biw.1. human. [Q7Z591-6]

Organism-specific databases

CTD80709.
GeneCardsGC09M117096.
HGNCHGNC:24108. AKNA.
MIM605729. gene.
neXtProtNX_Q7Z591.
PharmGKBPA134908332.
HUGESearch...
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG73466.
HOVERGENHBG097463.
OMAPEAMRME.
OrthoDBEOG754HQ8.
PhylomeDBQ7Z591.
TreeFamTF336885.

Gene expression databases

BgeeQ7Z591.
GenevestigatorQ7Z591.

Family and domain databases

InterProIPR022150. TF_AT-hook.
[Graphical view]
PfamPF12443. AKNA. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSAKNA. human.
GenomeRNAi80709.
NextBio71009.
PMAP-CutDBQ7Z591.
PROQ7Z591.
SOURCESearch...

Entry information

Entry nameAKNA_HUMAN
AccessionPrimary (citable) accession number: Q7Z591
Secondary accession number(s): Q05BK5 expand/collapse secondary AC list , Q5T535, Q5T536, Q5T537, Q64FX6, Q64FX7, Q64FX8, Q64FY2, Q6ZMK0, Q6ZNL2, Q6ZTX0, Q8TET1, Q8TF33, Q96RR9, Q9H7P7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 29, 2007
Last modified: April 16, 2014
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 9

Human chromosome 9: entries, gene names and cross-references to MIM