Q7Z4X3 (Q7Z4X3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: ATP-dependent RNA helicase EMBL AAP97252.1
Organism	Homo sapiens (Human) EMBL AAP97252.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	486 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the DEAD box helicase family. RuleBase RU000492

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Helicase RuleBase RU000492 EMBL AAP97252.1 Hydrolase
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent helicase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7Z4X3 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: B693BE730EA38B08	FASTA	486	55,968
	10 20 30 40 50 60 MTKAPPCKAY PKRPLLGRVL TPTRELAVQV KQHIDAVARF TGIKTAILVG GMSTQKQQRM 70 80 90 100 110 120 LNRRPEIVVA TPGRLWELIK EKHYHLRNLR QLRCLVVDEA DRMVEKGHFA ELSQLLEMLN 130 140 150 160 170 180 DSQYNPKRQT LVFSATLTLV HQAPARILHK KHTKKMDKTA KLDLLMQKIG MRGKPKVIDL 190 200 210 220 230 240 TRNEATVETL TETKIHCETD EKDFYLYYFL MQYPGRSLVF ANSISCIKRL SGLLKVLDIM 250 260 270 280 290 300 PLTLHACMHQ KQRLRNLEQF ARLEDCVLLA TDVAARGLDI PKVQHVIHYQ VPRTSEIYVH 310 320 330 340 350 360 RSGRTARATN EGLSLMLIGP EDVINFKKIY KTLKKDEDIP LFPVQTKYMD VVKERIRLAR 370 380 390 400 410 420 QIEKSEYRNF QACLHNSWIE QAAAALEIEL EEDMYKGGKA DQQEERRRQK QMKVLKKELR 430 440 450 460 470 480 HLLSQPLFTE SQKTKYPTQS GKPPLLVSAP SKSESALSCL SKQKKKKTKK PKEPQPEQPQ PSTSAN

References

[1]	"Cloning of a new human cDNA homologous to Mus musculus ATP-dependent RNA helicase." Yue P., Yu L., Zhao S.Y. Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF134475 mRNA. Translation: AAP97252.1.
IPI	IPI00911118.
UniGene	Hs.510328.
3D structure databases
HSSP	HSSP built from PDB template 1FUU based on UniProtKB P10081.
ProteinModelPortal	Q7Z4X3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG104200.
Family and domain databases
InterPro	IPR011545. DNA/RNA_helicase_DEAD/DEAH_N. IPR014001. Helicase_ATP-bd. IPR001650. Helicase_C. IPR000629. RNA-helicase_DEAD-box_CS. [Graphical view]
Pfam	PF00270. DEAD. 1 hit. PF00271. Helicase_C. 1 hit. [Graphical view]
SMART	SM00487. DEXDc. 1 hit. SM00490. HELICc. 1 hit. [Graphical view]
PROSITE	PS00039. DEAD_ATP_HELICASE. 1 hit. PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7Z4X3_HUMAN

Accession

Primary (citable) accession number: Q7Z4X3

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	October 1, 2003
Last modified:	April 3, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.