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Protein
Submitted name:

Fibroblast growth factor 23

Gene

FGF23

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Fibroblast growth factor 23Imported
Gene namesi
Name:FGF23Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000237837.

Structurei

3D structure databases

ProteinModelPortaliQ7Z4T2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG051613.

Family and domain databases

InterProiIPR008996. Cytokine_IL1-like.
IPR028304. FGF23.
IPR002209. Fibroblast_GF_fam.
[Graphical view]
PANTHERiPTHR11486. PTHR11486. 1 hit.
PTHR11486:SF69. PTHR11486:SF69. 1 hit.
SUPFAMiSSF50353. SSF50353. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q7Z4T2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
HYFDPENCRF QHQTLENGYD VYHSPQYHFL VSLGRAKRAF LPGMNPPPYS
60 70 80 90 100
QFLSRRNEIP LIHFNTPIPR RHTRSAEDDS ERDPLNVLKP RARMTPAPAS
110 120 130 140
CSQELPSAED NSPMASDPLG VVRGGRVNTH AGGMGPEGCR PFAKFI
Length:146
Mass (Da):16,440
Last modified:October 1, 2003 - v1
Checksum:i53B4928A5326CF7B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY336491 Genomic DNA. Translation: AAP97433.1.
UniGeneiHs.287370.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY336491 Genomic DNA. Translation: AAP97433.1.
UniGeneiHs.287370.

3D structure databases

ProteinModelPortaliQ7Z4T2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000237837.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG051613.

Family and domain databases

InterProiIPR008996. Cytokine_IL1-like.
IPR028304. FGF23.
IPR002209. Fibroblast_GF_fam.
[Graphical view]
PANTHERiPTHR11486. PTHR11486. 1 hit.
PTHR11486:SF69. PTHR11486:SF69. 1 hit.
SUPFAMiSSF50353. SSF50353. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Codon 239 ACG>ATG mutation of FGF-23 gene in autosomal dominant hypophosphatemic rickets family."
    Xia W., Pei Y., Xing X., Ning Z., Meng X., Li M., Zhou X.
    Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ7Z4T2_HUMAN
AccessioniPrimary (citable) accession number: Q7Z4T2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: June 24, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.