Q7Z4Q4 (Q7Z4Q4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Galactokinase 2 variant EMBL AAP97708.1

Submitted name:
Uncharacterized protein Ensembl ENSP00000316632

Gene names

Name:

GALK2 Ensembl ENSP00000316632

Organism

Homo sapiens (Human) EMBL AAP97708.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the GHMP kinase family. RuleBase RU004209

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU003563 Nucleotide-binding
Molecular function	Kinase RuleBase RU003563 EMBL AAP97708.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW galactokinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7Z4Q4 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 66D4925D605D1A4F	FASTA	447	49,235
	10 20 30 40 50 60 MPVLYDRLLK LKEMFNSKFG SIPKFYVRAP GRVNIIGEHI DYCGYSVLPM AVEQDVLIAV 70 80 90 100 110 120 EPVKTYALQL ANTNPLYPDF STSANNIQID KTKPLWHNYF LCGLKGIQEH FGLSNLTGMN 130 140 150 160 170 180 CLVDGNIPPS SGLSSSSALV CCAGLVTLTV LGRNLSKVEL AEICAKSERY IGTEGGGMDQ 190 200 210 220 230 240 SISFLAEEGT AKLIEFSPLR ATDVKLPSGA VFVIANSCVE MNKAATSHFN IRVMECRLAA 250 260 270 280 290 300 KLLAKYKSLQ WDKVLRLEEV QAKLGISLEE MLLVTEDALH PEPYNPEEIC RCLGISLEEL 310 320 330 340 350 360 RTQILSPNTQ DVLIFKLYQR AKHVYSEAAR VLQFKKICEE APENMVQLLG ELMNQSHMSC 370 380 390 400 410 420 RDMYECSCPE LDQLVDICRK FGAQGSRLTG AGWGGCTVSM VPADKLPSFL ANVHKAYYQR 430 440 SDGSLAPEKQ SLFATKPGGG ALVLLEA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the DNA sequence and duplication history of human chromosome 15." Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A. , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C. Nature 440:671-675(2006) [PubMed: 16572171] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Guo J.H., Zan Q., Yu L. Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC013452 Genomic DNA. No translation available. AC022306 Genomic DNA. No translation available. AC036102 Genomic DNA. No translation available. AF461816 mRNA. Translation: AAP97708.1.
IPI	IPI00186704.
RefSeq	NP_001001556.1. NM_001001556.1.
UniGene	Hs.122006. Hs.712959.
3D structure databases
ProteinModelPortal	Q7Z4Q4.
SMR	Q7Z4Q4. Positions 5-447.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7Z4Q4.
Proteomic databases
PRIDE	Q7Z4Q4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000327171; ENSP00000316632; ENSG00000156958.
GeneID	2585.
KEGG	hsa:2585.
NMPDR	fig|9606.3.peg.10687.
UCSC	uc001zxi.1. human.
Organism-specific databases
CTD	2585.
HGNC	HGNC:4119. GALK2.
GenAtlas	Search...
Phylogenomic databases
GeneTree	ENSGT00530000063433.
HOVERGEN	HBG051696.
PhylomeDB	Q7Z4Q4.
Gene expression databases
ArrayExpress	Q7Z4Q4.
Bgee	Q7Z4Q4.
Family and domain databases
InterPro	IPR000705. Galactokinase. IPR019741. Galactokinase_CS. IPR019539. GalKase_gal-bd. IPR006204. GHMP_kinase. IPR013750. GHMP_kinase_C. IPR006203. GHMP_knse_ATP-bd_CS. IPR006206. Mevalonate/galactokinase. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. [Graphical view]
Gene3D	G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KO	K00849.
Pfam	PF10509. GalKase_gal_bdg. 1 hit. PF08544. GHMP_kinases_C. 1 hit. PF00288. GHMP_kinases_N. 1 hit. [Graphical view]
PIRSF	PIRSF000530. Galactokinase. 1 hit.
PRINTS	PR00473. GALCTOKINASE. PR00959. MEVGALKINASE.
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMs	TIGR00131. Gal_kin. 1 hit.
PROSITE	PS00106. GALACTOKINASE. 1 hit. PS00627. GHMP_KINASES_ATP. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	10227.

Entry information

Entry name

Q7Z4Q4_HUMAN

Accession

Primary (citable) accession number: Q7Z4Q4

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	October 1, 2003
Last modified:	November 16, 2011
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.