Unreviewed, UniProtKB/TrEMBL Q7Z4M8 (Q7Z4M8_HUMAN)

Names and origin

Protein names

Submitted name:
    5-methyltetrahydrofolate-homocysteine methyltransferase reductase EMBL AAH54816.2

Gene names

Name:

MTRR EMBL AAH54816.2

Organism

Homo sapiens (Human) EMBL AAH54816.2

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	698 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Molecular function	Methyltransferase Transferase
Gene Ontology (GO)
Molecular function	FMN binding Inferred from electronic annotation. Source: InterPro electron carrier activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro methyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7Z4M8-1 [UniParc]. Last modified April 3, 2007. Version 2. Checksum: D4B394F0B24A07E5	FASTA	698	77,674
	10 20 30 40 50 60 MRRFLLLYAT QQGQAKAIAE EICEQAVVHG FSADLHCISE SDKYDLKTET APLVVVVSTT 70 80 90 100 110 120 GTGDPPDTAR KFVKEIQNQT LPVDFFAHLR YGLLGLGDSE YTYFCNGGKI IDKRLQELGA 130 140 150 160 170 180 RHFYDTGHAD DCVGLELVVE PWIAGLWPAL RKHFRSSRGQ EEISGALPVA SPASSRTDLV 190 200 210 220 230 240 KSELLHIESQ VELLRFDDSG RKDSEVLKQN AVNSNQSNVV IEDFESSLTR SVPPLSQASL 250 260 270 280 290 300 NIPGLPPEYL QVHLQESLGQ EESQVSVTSA DPVFQVPISK AVQLTTNDAI KTTLLVELDI 310 320 330 340 350 360 SNTDFSYQPG DAFSVICPNS DSEVQSLLQR LQLEDKREHC VLLKIKADTK KKGATLPQHI 370 380 390 400 410 420 PAGCSLQFIF TWCLEIRAIP KKAFLRALVD YTSDSAEKRR LQELCSKQGA ADYSRFVRDA 430 440 450 460 470 480 CACLLDLLLA FPSCQPPLSL LLEHLPKLQP RPYSCASSSL FHPGKLHFVF NIVEFLSTAT 490 500 510 520 530 540 TEVLRKGVCT GWLALLVASV LQPNIHASHE DSGKALAPKI SISPRTTNSF HLPDDPSIPI 550 560 570 580 590 600 IMVGPGTGIA PFIGFLQHRE KLQEQHPDGN FGAMWLFFGC RHKDRDYLFR KELRHFLKHG 610 620 630 640 650 660 ILTHLKVSFS RDAPVGEEEA PAKYVQDNIQ LHGQQVARIL LQENGHIYVC GDAKNMAKDV 670 680 690 HDALVQIISK EVGVEKLEAM KTLATLKEEK RYLQDIWS

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lung EMBL AAH54816.2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC054816 mRNA. Translation: AAH54816.2.
RefSeq	NP_002445.2.
UniGene	Hs.481551
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000124275. Homo sapiens. [Contig view]
GeneID	4552.
KEGG	hsa:4552.
NMPDR	fig|9606.3.peg.25040.
Organism-specific databases
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q7Z4M8.
Gene expression databases
ArrayExpress	Q7Z4M8.
Family and domain databases
InterPro	IPR003097. FAD-binding_1. IPR017927. Fd_Rdtase_FAD-bd. IPR001094. Flavdoxin_like. IPR008254. Flavodoxin/NO_synth. IPR001709. Flavoprot_Pyr_Nucl_cyt_Rdtase. IPR001433. OxRdtase_FAD/NAD_bd. [Graphical view]
Pfam	PF00667. FAD_binding_1. 1 hit. PF00258. Flavodoxin_1. 1 hit. PF00175. NAD_binding_1. 1 hit. [Graphical view]
PRINTS	PR00369. FLAVODOXIN. PR00371. FPNCR.
PROSITE	PS51384. FAD_FR. 1 hit. PS50902. FLAVODOXIN_LIKE. 1 hit. [Graphical view]
Other Resources
NextBio	17541.

Entry information

Entry name

Q7Z4M8_HUMAN

Accession

Primary (citable) accession number: Q7Z4M8

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	April 3, 2007
Last modified:	November 25, 2008
This is version 42 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)