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Q7Z4M2 (Q7Z4M2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:RASA1 EMBL AAH54891.1
OrganismHomo sapiens (Human) EMBL AAH54891.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length313 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 SH3 domain. RuleBase RU003338

Contains SH2 domain. SAAS SAAS000980

Contains SHdomain. SAAS SAAS000980

Ontologies

Keywords
   DomainSH3 domain SAAS SAAS000980 RuleBase RU003338
   Technical term3D-structure PDB 2GSB
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue3131 EMBL AAH54891.1

Sequences

Sequence LengthMass (Da)Tools
Q7Z4M2 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: B3A344CA87995F26

FASTA31336,565
        10         20         30         40         50         60 
MKGWYHGKLD RTIAEERLRQ AGKSGSYLIR ESDRRPGSFV LSFLSQMNVV NHFRIIAMCG 

        70         80         90        100        110        120 
DYYIGGRRFS SLSDLIGYYS HVSCLLKGEK LLYPVAPPEP VEDRRRVRAI LPYTKVPDTD 

       130        140        150        160        170        180 
EISFLKGDMF IVHNELEDGW MWVTNLRTDE QGLIVEDLVE EVGREEDPHE GKIWFHGKIS 

       190        200        210        220        230        240 
KQEAYNLLMT VGQVCSFLVR PSDNTPGDYS LYFRTNENIQ RFKICPTPNN QFMMGGRYYN 

       250        260        270        280        290        300 
SIGDIIDHYR KEQIVEGYYL KEPVPMQDQE QVLNDTVDGK EIYNTIRRKT KDAFYKNIVK 

       310 
KGYLLKKKKK KKK 

« Hide

References

« Hide 'large scale' references
[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Placenta EMBL AAH54891.1.
[2]"Solution structure of the second SH2 domain of human Ras GTPase-activating protein 1."
Kurosaki C., Suetake T., Yoshida M., Hayashi F., Yokoyma S.
Submitted (APR-2006) to the PDB data bank
Cited for: STRUCTURE BY NMR OF 164-269.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC054891 mRNA. Translation: AAH54891.1.
UniGeneHs.664080.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2GSBNMR-A164-269[»]
ProteinModelPortalQ7Z4M2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG060735.

Enzyme and pathway databases

SignaLinkQ7Z4M2.

Family and domain databases

Gene3D3.30.505.10. 2 hits.
InterProIPR000980. SH2.
IPR001452. SH3_domain.
[Graphical view]
PfamPF00017. SH2. 2 hits.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSPR00401. SH2DOMAIN.
SMARTSM00252. SH2. 2 hits.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMSSF50044. SSF50044. 1 hit.
SSF55550. SSF55550. 2 hits.
PROSITEPS50001. SH2. 2 hits.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSRASA1. human.

Entry information

Entry nameQ7Z4M2_HUMAN
AccessionPrimary (citable) accession number: Q7Z4M2
Entry history
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: April 16, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.