Q7Z4J5 (Q7Z4J5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related EMBL AAP88873.1

Submitted name:
Runt-related transcription factor 1; translocated to, 1 (Cyclin D-related) EMBL AAH67078.2
Submitted name:
Runt-related transcription factor 1; translocated to, 1 (Cyclin D-related), isoform CRA_e EMBL EAW91685.1
Submitted name:
Uncharacterized protein Ensembl ENSP00000353504 Ensembl ENSP00000390137 Ensembl ENSP00000428742

Gene names

Name:	RUNX1T1 Ensembl ENSP00000353504 Ensembl ENSP00000390137 Ensembl ENSP00000428742 EMBL AAH67078.2
ORF Names:	hCG_20715 EMBL EAW91685.1

Organism

Homo sapiens (Human) EMBL AAP88873.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	567 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	Metal-binding SAAS SAAS002893
Molecular function	Cyclin EMBL AAP88873.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7Z4J5 [UniParc]. Last modified October 1, 2003. Version 1. Checksum: 44AADF2EC7032050	FASTA	567	63,212
	10 20 30 40 50 60 MPDSPVDVKT QSRLTPPTMP PPPTTQGAPR TSSFTPTTLT NGTSHSPTAL NGAPSPPNGF 70 80 90 100 110 120 SNGPSSSSSS SLANQQLPPA CGARQLSKLK RFLTTLQQFG NDISPEIGER VRTLVLGLVN 130 140 150 160 170 180 STLTIEEFHS KLQEATNFPL RPFVIPFLKA NLPLLQRELL HCARLAKQNP AQYLAQHEQL 190 200 210 220 230 240 LLDASTTSPV DSSELLLDVN ENGKRRTPDR TKENGFDREP LHSEHPSKRP CTISPGQRYS 250 260 270 280 290 300 PNNGLSYQPN GLPHPTPPPP QHYRLDDMAI AHHYRDSYRH PSHRDLRDRN RPMGLHGTRQ 310 320 330 340 350 360 EEMIDHRLTD REWAEEWKHL DHLLNCIMDM VEKTRRSLTV LRRCQEADRE ELNYWIRRYS 370 380 390 400 410 420 DAEDLKKGGG SSSSHSRQQS PVNPDPVALD AHREFLHRPA SGYVPEEIWK KAEEAVNEVK 430 440 450 460 470 480 RQAMTELQKA VSEAERKAHD MITTERAKME RTVAEAKRQA AEDALAVINQ QEDSSESCWN 490 500 510 520 530 540 CGRKASETCS GCNTARYCGS FCQHKDWEKH HHICGQTLQA QQQGDTPAVS SSVTPNSGAG 550 560 SPMDTPPAAT PRSTTPGTPS TIETTPR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DNA sequence and analysis of human chromosome 8." Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., Asakawa T. , Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Gloeckner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., O'Neill K., Parker S.C.J., Polley A., Raymond C.K., Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N., Lander E.S. Nature 439:331-335(2006) [PubMed: 16421571] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Muscle EMBL AAH67078.2.
[3]	Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A. Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.
[5]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC103680 Genomic DNA. No translation available. AC104339 Genomic DNA. No translation available. AF181450 Genomic DNA. No translation available. BC067078 mRNA. Translation: AAH67078.2. BT009871 mRNA. Translation: AAP88873.1. CH471060 Genomic DNA. Translation: EAW91685.1.
IPI	IPI00375987.
RefSeq	NP_001185555.1. NM_001198626.1. NP_001185556.1. NM_001198627.1. NP_001185557.1. NM_001198628.1. NP_001185558.1. NM_001198629.1. NP_001185559.1. NM_001198630.1. NP_001185560.1. NM_001198631.1. NP_001185561.1. NM_001198632.1. NP_001185562.1. NM_001198633.1. NP_001185608.1. NM_001198679.1. NP_783553.1. NM_175635.2. NP_783554.1. NM_175636.2.
UniGene	Hs.368431.
3D structure databases
ProteinModelPortal	Q7Z4J5.
SMR	Q7Z4J5. Positions 82-179, 305-363, 400-430, 473-522.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-1439547.
STRING	Q7Z4J5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000360348; ENSP00000353504; ENSG00000079102. ENST00000422361; ENSP00000390137; ENSG00000079102. ENST00000520724; ENSP00000428742; ENSG00000079102.
GeneID	862.
KEGG	hsa:862.
UCSC	uc003yfb.1. human.
Organism-specific databases
CTD	862.
HGNC	HGNC:1535. RUNX1T1.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	HBG000169.
OrthoDB	EOG4TB4B6.
Gene expression databases
ArrayExpress	Q7Z4J5.
Bgee	Q7Z4J5.
Family and domain databases
InterPro	IPR013289. ETO. IPR013290. MTG8. IPR014896. NHR2. IPR003894. TAFH_NHR1. IPR002893. Znf_MYND. [Graphical view]
KO	K10053.
Pfam	PF08788. NHR2. 1 hit. PF07531. TAFH. 1 hit. PF01753. zf-MYND. 1 hit. [Graphical view]
PRINTS	PR01875. ETOFAMILY. PR01876. MTG8PROTEIN.
SMART	SM00549. TAFH. 1 hit. [Graphical view]
PROSITE	PS51119. TAFH. 1 hit. PS01360. ZF_MYND_1. 1 hit. PS50865. ZF_MYND_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	3586.

Entry information

Entry name

Q7Z4J5_HUMAN

Accession

Primary (citable) accession number: Q7Z4J5
Secondary accession number(s): Q6NXH1

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	October 1, 2003
Last modified:	November 16, 2011
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.