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Q7Z475 (CTR3L_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative cationic amino acid transporter 3-like protein
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length142 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceUncertain

General annotation (Comments)

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. [View classification]

Caution

Could be the product of a pseudogene. In contrast to other members of the family, it is much shorter and lacks the N-terminal part.

Ontologies

Keywords
   Cellular componentMembrane
   DomainSignal
Transmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionamino acid transmembrane transporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 142123Putative cationic amino acid transporter 3-like protein
PRO_0000341234

Regions

Topological domain20 – 9475Extracellular Potential
Transmembrane95 – 11521Helical; Potential
Topological domain116 – 14227Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
Q7Z475 [UniParc].

Last modified January 22, 2014. Version 3.
Checksum: D3877634DA898A2E

FASTA14215,392
        10         20         30         40         50         60 
MGPHRLWMCL SACCPAVHAM PGIGPLAQTP VLWRADLHRS GCVAAGAHCG IHFHRLETAP 

        70         80         90        100        110        120 
EQHSSLLQGP PVACSPLVSI SAHVYLMMQM TTETWAQCGV WMLIGFAMYF GYGIPHSLEN 

       130        140 
NQQPPASSSQ TPHENIPSPL LN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC011487 Genomic DNA. No translation available.
UniGeneHs.631571.

3D structure databases

ProteinModelPortalQ7Z475.
ModBaseSearch...
MobiDBSearch...

Polymorphism databases

DMDM190358840.

Proteomic databases

PaxDbQ7Z475.
PRIDEQ7Z475.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

neXtProtNX_Q7Z475.

Phylogenomic databases

eggNOGKOG1286.
HOGENOMHOG000112050.
InParanoidQ7Z475.
OMAHENIPSP.

Gene expression databases

GenevestigatorQ7Z475.

Family and domain databases

InterProIPR002293. AA/rel_permease1.
IPR029485. CAT_C.
[Graphical view]
PANTHERPTHR11785. PTHR11785. 1 hit.
PfamPF13906. AA_permease_C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCTR3L_HUMAN
AccessionPrimary (citable) accession number: Q7Z475
Secondary accession number(s): M0QY13
Entry history
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: January 22, 2014
Last modified: July 9, 2014
This is version 65 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 19

Human chromosome 19: entries, gene names and cross-references to MIM