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Protein

Protein MON2 homolog

Gene

MON2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

May be required for traffic between late Golgi and early endosomes.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MON2 homolog
Alternative name(s):
Protein SF21
Gene namesi
Name:MON2
Synonyms:KIAA1040, SF21
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:29177. MON2.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: GOC
  • extracellular exosome Source: UniProtKB
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA143485545.

Polymorphism and mutation databases

BioMutaiMON2.
DMDMi156632594.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedCombined sources
Chaini2 – 17171716Protein MON2 homologPRO_0000297902Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserineCombined sources
Modified residuei205 – 2051PhosphoserineCombined sources
Modified residuei537 – 5371PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ7Z3U7.
MaxQBiQ7Z3U7.
PaxDbiQ7Z3U7.
PeptideAtlasiQ7Z3U7.
PRIDEiQ7Z3U7.

PTM databases

iPTMnetiQ7Z3U7.
PhosphoSiteiQ7Z3U7.

Expressioni

Gene expression databases

BgeeiQ7Z3U7.
CleanExiHS_MON2.
ExpressionAtlasiQ7Z3U7. baseline and differential.
GenevisibleiQ7Z3U7. HS.

Organism-specific databases

HPAiHPA038697.
HPA057607.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
GGA1Q9UJY52EBI-358882,EBI-447141

Protein-protein interaction databases

BioGridi116680. 17 interactions.
IntActiQ7Z3U7. 10 interactions.
MINTiMINT-1149344.
STRINGi9606.ENSP00000377252.

Family & Domainsi

Sequence similaritiesi

Belongs to the MON2 family.Curated

Phylogenomic databases

eggNOGiKOG0929. Eukaryota.
KOG1848. Eukaryota.
ENOG410XQA8. LUCA.
GeneTreeiENSGT00390000013286.
HOGENOMiHOG000008113.
HOVERGENiHBG108142.
InParanoidiQ7Z3U7.
OMAiDCQVIEL.
OrthoDBiEOG7C8GGF.
TreeFamiTF314287.

Family and domain databases

Gene3Di1.25.10.10. 3 hits.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR032629. DCB_dom.
IPR032817. Mon2_C.
IPR015403. Sec7_C.
IPR032691. Sec7_N.
[Graphical view]
PfamiPF16213. DCB. 1 hit.
PF09324. DUF1981. 1 hit.
PF16206. Mon2_C. 1 hit.
PF12783. Sec7_N. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 5 hits.

Sequences (5)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 5 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q7Z3U7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSGTSSPEAV KKLLENMQSD LRALSLECKK KFPPVKEAAE SGIIKVKTIA
60 70 80 90 100
ARNTEILAAL KENSSEVVQP FLMGCGTKEP KITQLCLAAI QRLMSHEVVS
110 120 130 140 150
ETAAGNIINM LWQLMENSLE ELKLLQTVLV LLTTNTVVHD EALSKAIVLC
160 170 180 190 200
FRLHFTKDNI TNNTAAATVR QVVTVVFERM VAEDERHRDI IEQPVLVQGN
210 220 230 240 250
SNRRSVSTLK PCAKDAYMLF QDLCQLVNAD APYWLVGMTE MTRTFGLELL
260 270 280 290 300
ESVLNDFPQV FLQHQEFSFL LKERVCPLVI KLFSPNIKFR QGSSTSSSPA
310 320 330 340 350
PVEKPYFPIC MRLLRVVSVL IKQFYSLLVT ECEIFLSLLV KFLDADKPQW
360 370 380 390 400
LRAVAVESIH RFCVQPQLLR SFCQSYDMKQ HSTKVFRDIV NALGSFIQSL
410 420 430 440 450
FLVPPTGNPA TSNQAGNNNL GGSVSAPANS GMVGIGGGVT LLPAFEYRGT
460 470 480 490 500
WIPILTITVQ GSAKATYLEM LDKVEPPTIP EGYAMSVAFH CLLDLVRGIT
510 520 530 540 550
SMIEGELGEL ETECQTTTEE GSSPTQSTEQ QDLQSTSDQM DKEIVSRAVW
560 570 580 590 600
EEMVNACWCG LLAALSLLLD ASTDEAATEN ILKAELTMAA LCGRLGLVTS
610 620 630 640 650
RDAFITAICK GSLPPHYALT VLNTTTAATL SNKSYSVQGQ SVMMISPSSE
660 670 680 690 700
SHQQVVAVGQ PLAVQPQGTV MLTSKNIQCM RTLLNLAHCH GAVLGTSWQL
710 720 730 740 750
VLATLQHLVW ILGLKPSSGG ALKPGRAVEG PSTVLTTAVM TDLPVISNIL
760 770 780 790 800
SRLFESSQYL DDVSLHHLIN ALCSLSLEAM DMAYGNNKEP SLFAVAKLLE
810 820 830 840 850
TGLVNMHRIE ILWRPLTGHL LEVCQHPNSR MREWGAEALT SLIKAGLTFN
860 870 880 890 900
HDPPLSQNQR LQLLLLNPLK EMSNINHPDI RLKQLECVLQ ILQSQGDSLG
910 920 930 940 950
PGWPLVLGVM GAIRNDQGES LIRTAFQCLQ LVVTDFLPTM PCTCLQIVVD
960 970 980 990 1000
VAGSFGLHNQ ELNISLTSIG LLWNISDYFF QRGETIEKEL NKEEAAQQKQ
1010 1020 1030 1040 1050
AEEKGVVLNR PFHPAPPFDC LWLCLYAKLG ELCVDPRPAV RKSAGQTLFS
1060 1070 1080 1090 1100
TIGAHGTLLQ HSTWHTVIWK VLFHLLDRVR ESSTTADKEK IESGGGNILI
1110 1120 1130 1140 1150
HHSRDTAEKQ WAETWVLTLA GVARIFNTRR YLLQPLGDFS RAWDVLLDHI
1160 1170 1180 1190 1200
QSAALSKNNE VSLAALKSFQ EILQIVSPVR DSDKPETPPV VNVPVPVLIG
1210 1220 1230 1240 1250
PISGMSRPFV RTDSIGEKLG RYSSSEPPIV TDELEDLNLW WAAWNTWYRI
1260 1270 1280 1290 1300
GSESTKPPIT FDKLTFIPSQ PFLTALIQIF PALYQHIKTG FNMDDLQKLG
1310 1320 1330 1340 1350
VILHSAISVP ISSDASPFIL PSYTEAVLTS LQEAVLTALD VLQKAICVGP
1360 1370 1380 1390 1400
ENMQIMYPAI FDQLLAFVEF SCKPPQYGQL ETKHIANAKY NQIQLFAPAE
1410 1420 1430 1440 1450
WVALNYVPFA ERSLEVVVDL YQKTACHKAV VNEKVLQNII KTLRVPLSLK
1460 1470 1480 1490 1500
YSCPSESTWK LAVSSLLRVL SIGLPVARQH ASSGKFDSMW PELANTFEDF
1510 1520 1530 1540 1550
LFTKSIPPDN LSIQEFQRNE NIDVEVVQLI SNEILPYANF IPKEFVGQIM
1560 1570 1580 1590 1600
TMLNKGSIHS QSSSFTEAEI DIRLREEFSK MCFETLLQFS FSNKVTTPQE
1610 1620 1630 1640 1650
GYISRMALSV LLKRSQDVLH RYIEDERLSG KCPLPRQQVT EIIFVLKAVS
1660 1670 1680 1690 1700
TLIDSLKKTQ PENVDGNTWA QVIALYPTLV ECITCSSSEV CSALKEALVP
1710
FKDFMQPPAS RVQNGES
Length:1,717
Mass (Da):190,359
Last modified:September 3, 2014 - v3
Checksum:iA95DCDF2A69BC0D2
GO
Isoform 2 (identifier: Q7Z3U7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1664-1675: VDGNTWAQVIAL → ACISLFGIPPYF
     1676-1717: Missing.

Note: No experimental confirmation available.
Show »
Length:1,675
Mass (Da):185,855
Checksum:iB91F7B0CF95A6FB8
GO
Isoform 3 (identifier: Q7Z3U7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1125: Missing.
     1126-1136: FNTRRYLLQPL → MIIVFFSLPNI
     1393-1398: Missing.

Show »
Length:586
Mass (Da):65,692
Checksum:i831DB2B1E162C8F2
GO
Isoform 5 (identifier: Q7Z3U7-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1393-1398: Missing.

Note: No experimental confirmation available.
Show »
Length:1,711
Mass (Da):189,689
Checksum:iF889187A46C1D400
GO
Isoform 6 (identifier: Q7Z3U7-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     611-634: GSLPPHYALTVLNTTTAATLSNKS → A
     1393-1398: Missing.

Note: No experimental confirmation available. Gene prediction based on EST data.
Show »
Length:1,688
Mass (Da):187,320
Checksum:i7DC2953A2BFE5D24
GO

Sequence cautioni

The sequence BAA82992.3 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti163 – 1631N → D in CAD97657 (PubMed:17974005).Curated
Sequence conflicti197 – 1971V → I in CAD97657 (PubMed:17974005).Curated
Sequence conflicti238 – 2381M → T in CAD97657 (PubMed:17974005).Curated
Sequence conflicti268 – 2681S → G in CAD89933 (PubMed:17974005).Curated
Sequence conflicti650 – 6501E → G in CAD97657 (PubMed:17974005).Curated
Sequence conflicti734 – 7341V → A in CAD89933 (PubMed:17974005).Curated
Sequence conflicti822 – 8221E → EK in BAA82992 (PubMed:10470851).Curated
Sequence conflicti822 – 8221E → EK in AAI41818 (PubMed:15489334).Curated
Sequence conflicti822 – 8221E → EK in AAI42711 (PubMed:15489334).Curated
Sequence conflicti822 – 8221E → EK in AAI51242 (PubMed:15489334).Curated
Sequence conflicti1002 – 10021E → K in CAD89933 (PubMed:17974005).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti548 – 5481A → T.2 Publications
Corresponds to variant rs10219555 [ dbSNP | Ensembl ].
VAR_034689

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 11251125Missing in isoform 3. 1 PublicationVSP_027389Add
BLAST
Alternative sequencei611 – 63424GSLPP…LSNKS → A in isoform 6. CuratedVSP_055628Add
BLAST
Alternative sequencei1126 – 113611FNTRRYLLQPL → MIIVFFSLPNI in isoform 3. 1 PublicationVSP_027390Add
BLAST
Alternative sequencei1393 – 13986Missing in isoform 3, isoform 5 and isoform 6. 2 PublicationsVSP_027391
Alternative sequencei1664 – 167512VDGNT…QVIAL → ACISLFGIPPYF in isoform 2. 1 PublicationVSP_027392Add
BLAST
Alternative sequencei1676 – 171742Missing in isoform 2. 1 PublicationVSP_027393Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB017814 mRNA. Translation: BAC11707.1.
AB028963 mRNA. Translation: BAA82992.3. Different initiation.
AK092646 mRNA. Translation: BAC03935.1.
AL834320 mRNA. Translation: CAD38989.1.
BX537415 mRNA. Translation: CAD97657.1.
AL833066 mRNA. Translation: CAD89933.1.
AC026115 Genomic DNA. No translation available.
AC079035 Genomic DNA. No translation available.
BC136621 mRNA. Translation: AAI36622.1.
BC141817 mRNA. Translation: AAI41818.1.
BC142710 mRNA. Translation: AAI42711.1.
BC151241 mRNA. Translation: AAI51242.1.
CCDSiCCDS31849.1. [Q7Z3U7-1]
CCDS61175.1. [Q7Z3U7-6]
CCDS61177.1. [Q7Z3U7-2]
CCDS61178.1. [Q7Z3U7-5]
RefSeqiNP_001265398.1. NM_001278469.1. [Q7Z3U7-2]
NP_001265399.1. NM_001278470.1. [Q7Z3U7-5]
NP_055841.2. NM_015026.2. [Q7Z3U7-1]
UniGeneiHs.389378.

Genome annotation databases

EnsembliENST00000393629; ENSP00000377249; ENSG00000061987. [Q7Z3U7-5]
ENST00000393630; ENSP00000377250; ENSG00000061987. [Q7Z3U7-1]
ENST00000546600; ENSP00000447407; ENSG00000061987. [Q7Z3U7-2]
ENST00000552738; ENSP00000449215; ENSG00000061987. [Q7Z3U7-6]
GeneIDi23041.
KEGGihsa:23041.
UCSCiuc001sre.4. human. [Q7Z3U7-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB017814 mRNA. Translation: BAC11707.1.
AB028963 mRNA. Translation: BAA82992.3. Different initiation.
AK092646 mRNA. Translation: BAC03935.1.
AL834320 mRNA. Translation: CAD38989.1.
BX537415 mRNA. Translation: CAD97657.1.
AL833066 mRNA. Translation: CAD89933.1.
AC026115 Genomic DNA. No translation available.
AC079035 Genomic DNA. No translation available.
BC136621 mRNA. Translation: AAI36622.1.
BC141817 mRNA. Translation: AAI41818.1.
BC142710 mRNA. Translation: AAI42711.1.
BC151241 mRNA. Translation: AAI51242.1.
CCDSiCCDS31849.1. [Q7Z3U7-1]
CCDS61175.1. [Q7Z3U7-6]
CCDS61177.1. [Q7Z3U7-2]
CCDS61178.1. [Q7Z3U7-5]
RefSeqiNP_001265398.1. NM_001278469.1. [Q7Z3U7-2]
NP_001265399.1. NM_001278470.1. [Q7Z3U7-5]
NP_055841.2. NM_015026.2. [Q7Z3U7-1]
UniGeneiHs.389378.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116680. 17 interactions.
IntActiQ7Z3U7. 10 interactions.
MINTiMINT-1149344.
STRINGi9606.ENSP00000377252.

PTM databases

iPTMnetiQ7Z3U7.
PhosphoSiteiQ7Z3U7.

Polymorphism and mutation databases

BioMutaiMON2.
DMDMi156632594.

Proteomic databases

EPDiQ7Z3U7.
MaxQBiQ7Z3U7.
PaxDbiQ7Z3U7.
PeptideAtlasiQ7Z3U7.
PRIDEiQ7Z3U7.

Protocols and materials databases

DNASUi23041.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000393629; ENSP00000377249; ENSG00000061987. [Q7Z3U7-5]
ENST00000393630; ENSP00000377250; ENSG00000061987. [Q7Z3U7-1]
ENST00000546600; ENSP00000447407; ENSG00000061987. [Q7Z3U7-2]
ENST00000552738; ENSP00000449215; ENSG00000061987. [Q7Z3U7-6]
GeneIDi23041.
KEGGihsa:23041.
UCSCiuc001sre.4. human. [Q7Z3U7-1]

Organism-specific databases

CTDi23041.
GeneCardsiMON2.
H-InvDBHIX0010775.
HGNCiHGNC:29177. MON2.
HPAiHPA038697.
HPA057607.
neXtProtiNX_Q7Z3U7.
PharmGKBiPA143485545.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0929. Eukaryota.
KOG1848. Eukaryota.
ENOG410XQA8. LUCA.
GeneTreeiENSGT00390000013286.
HOGENOMiHOG000008113.
HOVERGENiHBG108142.
InParanoidiQ7Z3U7.
OMAiDCQVIEL.
OrthoDBiEOG7C8GGF.
TreeFamiTF314287.

Miscellaneous databases

ChiTaRSiMON2. human.
GeneWikiiMON2.
GenomeRNAii23041.
PROiQ7Z3U7.

Gene expression databases

BgeeiQ7Z3U7.
CleanExiHS_MON2.
ExpressionAtlasiQ7Z3U7. baseline and differential.
GenevisibleiQ7Z3U7. HS.

Family and domain databases

Gene3Di1.25.10.10. 3 hits.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR032629. DCB_dom.
IPR032817. Mon2_C.
IPR015403. Sec7_C.
IPR032691. Sec7_N.
[Graphical view]
PfamiPF16213. DCB. 1 hit.
PF09324. DUF1981. 1 hit.
PF16206. Mon2_C. 1 hit.
PF12783. Sec7_N. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 5 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Human homologue to C. elegans F11A10.4 hypothetical protein."
    Inagaki S.
    Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT THR-548.
    Tissue: Hippocampus.
  2. "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
    Kikuno R., Nagase T., Ishikawa K., Hirosawa M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 6:197-205(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
    Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
    DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION.
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    Tissue: Prostate.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT THR-548.
    Tissue: Amygdala and Spinal cord.
  6. "The finished DNA sequence of human chromosome 12."
    Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
    , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
    Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1071 (ISOFORMS 1/2).
  8. "Yeast Mon2p is a highly conserved protein that functions in the cytoplasm-to-vacuole transport pathway and is required for Golgi homeostasis."
    Efe J.A., Plattner F., Hulo N., Kressler D., Emr S.D., Deloche O.
    J. Cell Sci. 118:4751-4764(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.
  9. "Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus."
    Gillingham A.K., Whyte J.R.C., Panic B., Munro S.
    J. Biol. Chem. 281:2273-2280(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.
  10. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
    Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
    Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  11. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-205, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  13. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  14. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS], IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  15. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.

Entry informationi

Entry nameiMON2_HUMAN
AccessioniPrimary (citable) accession number: Q7Z3U7
Secondary accession number(s): A5D8U7
, A7E2Y0, B9EGP5, F8VWA6, F8W1Z6, Q86TA2, Q8N3I5, Q8NAI0, Q8NHE2, Q9UPW1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: September 3, 2014
Last modified: July 6, 2016
This is version 115 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.